scholarly journals Erratum: Corrigendum: Highly sensitive dual mode electrochemical platform for microRNA detection

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Pawan Jolly ◽  
Marina R. Batistuti ◽  
Anna Miodek ◽  
Pavel Zhurauski ◽  
Marcelo Mulato ◽  
...  
Keyword(s):  
Dual Mode ◽  
Microrna Detection ◽  
Highly Sensitive

scholarly journals Highly sensitive dual mode electrochemical platform for microRNA detection

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Pawan Jolly ◽  
Marina R. Batistuti ◽  
Anna Miodek ◽  
Pavel Zhurauski ◽  
Marcelo Mulato ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Dynamic Range ◽  
Electrochemical Impedance ◽  
Limit Of Detection ◽  
Dual Mode ◽  
Electrode Surfaces ◽  
Microrna Detection ◽  
Highly Sensitive ◽  
Detection Mode ◽  
Amplification Strategy

Abstract MicroRNAs (miRNAs) play crucial regulatory roles in various human diseases including cancer, making them promising biomarkers. However, given the low levels of miRNAs present in blood, their use as cancer biomarkers requires the development of simple and effective analytical methods. Herein, we report the development of a highly sensitive dual mode electrochemical platform for the detection of microRNAs. The platform was developed using peptide nucleic acids as probes on gold electrode surfaces to capture target miRNAs. A simple amplification strategy using gold nanoparticles has been employed exploiting the inherent charges of the nucleic acids. Electrochemical impedance spectroscopy was used to monitor the changes in capacitance upon any binding event, without the need for any redox markers. By using thiolated ferrocene, a complementary detection mode on the same sensor was developed where the increasing peaks of ferrocene were recorded using square wave voltammetry with increasing miRNA concentration. This dual-mode approach allows detection of miRNA with a limit of detection of 0.37 fM and a wide dynamic range from 1 fM to 100 nM along with clear distinction from mismatched target miRNA sequences. The electrochemical platform developed can be easily expanded to other miRNA/DNA detection along with the development of microarray platforms.

An anthracene–quinoline based dual-mode fluorometric–colorimetric sensor for the detection of Fe3+ and its application in live cell imaging

2021 ◽  
Author(s):  
Tahereh Tehrani ◽  
Soraia Meghdadi ◽  
Zohreh Salarvand ◽  
Behnam Tavakoli ◽  
Kiamars Eskandari ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Colorimetric Detection ◽  
Colorimetric Sensor ◽  
Live Cell ◽  
Dual Mode ◽  
Highly Sensitive

A highly sensitive anthracene–quinoline based dual-mode sensor has been synthesized and used for the fluorometric and colorimetric detection of Fe3+ and in live cell imaging.

Broadening the valid temperature range of optical thermometry through dual-mode design

2018 ◽  
Vol 6 (41) ◽  
pp. 11178-11183 ◽  
Author(s):  
Yan Gao ◽  
Yao Cheng ◽  
Tao Hu ◽  
Zeliang Ji ◽  
Hang Lin ◽  
...  
Keyword(s):  
Dual Mode ◽  
Temperature Range ◽  
Mode Design ◽  
Optical Thermometry ◽  
Highly Sensitive ◽  
Wide Range ◽  
Optical Thermometer

This study highlights a highly sensitive dual-mode optical thermometer Pr3+:Gd2ZnTiO6 for thermal readings over a wide range of temperature.

Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

2020 ◽  
Vol 56 (3) ◽  
pp. 470-473 ◽  
Author(s):  
Yanan Wu ◽  
Hong-Min Meng ◽  
Juan Chen ◽  
Kemei Jiang ◽  
Ran Yang ◽  
...  
Keyword(s):  
Sensitive Detection ◽  
Live Cells ◽  
Fluorescent Nanoprobe ◽  
Microrna Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

An accelerated DNAzyme-based fluorescent nanoprobe was developed for rapid and highly sensitive detection of microRNA in live cells.

scholarly journals Microparticle parking and isolation for highly sensitive microRNA detection

Lab on a Chip ◽  
2017 ◽  
Vol 17 (18) ◽  
pp. 3120-3128 ◽  
Author(s):  
Jae Jung Kim ◽  
Lynna Chen ◽  
Patrick S. Doyle
Keyword(s):  
Microfluidic Platform ◽  
Hydrogel Microparticles ◽  
Microrna Detection ◽  
Highly Sensitive ◽  
Monodisperse Droplets

We demonstrate a microfluidic platform that immobilizes hydrogel microparticles at defined locations, and encapsulates particles in monodisperse droplets for sensitive bioassays.

Sign in / Sign up

Export Citation Format

Share Document