scholarly journals Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to 3p21.31 in Chinese Population

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Juntao Ke ◽  
Jiao Lou ◽  
Rong Zhong ◽  
Xueqin Chen ◽  
Jiaoyuan Li ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
Risk Mapping ◽  
Colorectal Cancer Risk ◽  
Regulatory Variant

scholarly journals Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to Chromosome 5q31.1: A Post-GWAS Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0138478 ◽  
Author(s):  
Juntao Ke ◽  
Jiao Lou ◽  
Xueqin Chen ◽  
Jiaoyuan Li ◽  
Cheng Liu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Risk Mapping ◽  
Colorectal Cancer Risk ◽  
Gwas Study ◽  
Regulatory Variant

scholarly journals Common genetic variant rs3802842 in 11q23 contributes to colorectal cancer risk in Chinese population

Oncotarget ◽  
2017 ◽  
Vol 8 (42) ◽  
pp. 72227-72234
Author(s):  
Chunze Zhang ◽  
Xichuan Li ◽  
Weihua Zhang ◽  
Yijia Wang ◽  
Guanwei Fan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
Genetic Variant ◽  
Colorectal Cancer Risk ◽  
Common Genetic Variant

The association of XPC polymorphisms and tea drinking with colorectal cancer risk in a Chinese population

2010 ◽  
Vol 50 (3) ◽  
pp. 189-198 ◽  
Author(s):  
Yinyin Wu ◽  
Mingjuan Jin ◽  
Bing Liu ◽  
Xia Liang ◽  
Yunxian Yu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
Colorectal Cancer Risk ◽  
Tea Drinking

Dietary B vitamin and methionine intakes and risk for colorectal cancer: a case–control study in China

2020 ◽  
Vol 123 (11) ◽  
pp. 1277-1289 ◽  
Author(s):  
Chu-Yi Huang ◽  
Alinuer Abulimiti ◽  
Xin Zhang ◽  
Xiao-Li Feng ◽  
Hong Luo ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
Case Control Study ◽  
Case Control ◽  
B Vitamins ◽  
Colorectal Cancer Risk ◽  
Vitamin B ◽  
Nucleotide Synthesis ◽  
Control Study

AbstractB vitamins (including folate, vitamin B2, vitamin B6 and vitamin B12) and methionine are essential for methylation reactions, nucleotide synthesis, DNA stability and DNA repair. However, epidemiological evidence among Chinese populations is limited. The objective of this study was to evaluate B vitamins and methionine in relation to colorectal cancer risk in a Chinese population. A case–control study was conducted from July 2010 to April 2019. A total of 2502 patients with colorectal cancer were recruited along with 2538 age- (5-year interval) and sex-matched controls. Dietary data were collected using a validated FFQ. Multivariable logistic regression was used to assess OR and 95 % CI. The intake of folate, vitamin B2, vitamin B6 and vitamin B12 was inversely associated with colorectal cancer risk. The multivariable OR for the highest quartile v. the lowest quartile were 0·62 (95 % CI 0·51, 0·74; Ptrend < 0·001) for folate, 0·46 (95 % CI 0·38, 0·55; Ptrend < 0·001) for vitamin B2, 0·55 (95 % CI 0·46, 0·76; Ptrend < 0·001) for vitamin B6 and 0·72 (95 % CI 0·60, 0·86; Ptrend < 0·001) for vitamin B12. No statistically significant association was found between methionine intake and colorectal cancer risk. Stratified analysis by sex showed that the inverse associations between vitamin B12 and methionine intake and colorectal cancer risk were found only among women. This study indicated that higher intake of folate, vitamin B2, vitamin B6 and vitamin B12 was associated with decreased risk of colorectal cancer in a Chinese population.

scholarly journals SMAD7 rs4939827 variant contributes to colorectal cancer risk in Chinese population

Oncotarget ◽  
2017 ◽  
Vol 8 (25) ◽  
pp. 41125-41131 ◽  
Author(s):  
Chunze Zhang ◽  
Xichuan Li ◽  
Wenzheng Fu ◽  
Yijia Wang ◽  
Tao Wang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
Colorectal Cancer Risk

scholarly journals Identification of a functional variant for colorectal cancer risk mapping to chromosome 5q31.1

Oncotarget ◽  
2016 ◽  
Vol 7 (23) ◽  
pp. 35199-35207 ◽  
Author(s):  
Juntao Ke ◽  
Jiao Lou ◽  
Xueqin Chen ◽  
Jiaoyuan Li ◽  
Cheng Liu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Risk Mapping ◽  
Colorectal Cancer Risk ◽  
Functional Variant
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