scholarly journals Prognostic Role of C-Reactive Protein In Urological Cancers: A Meta-Analysis

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Liang Zhou ◽  
Xiang Cai ◽  
Qiang Liu ◽  
Zhong-Yu Jian ◽  
Hong Li ◽  
...  
Keyword(s):  
Meta Analysis ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein ◽  
Urological Cancers

scholarly journals Prognostic role of C-reactive protein in prostate cancer: a systematic review and meta-analysis

2014 ◽  
Vol 16 (3) ◽  
pp. 467 ◽  
Author(s):  
Qing Xu ◽  
Yi-Jing Chen ◽  
Zhu-Qing Liu ◽  
Li Chu ◽  
Jue-Min Fang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Systematic Review ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein

scholarly journals Prognostic Role of C-reactive Protein in Gastric Cancer: A Meta-analysis

2013 ◽  
Vol 14 (10) ◽  
pp. 5735-5740 ◽  
Author(s):  
Qing Yu ◽  
Xiong-Fei Yu ◽  
Shou-De Zhang ◽  
Hao-Hao Wang ◽  
Hai-Yong Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein

scholarly journals The Prognostic Role of Glasgow Prognostic Score and C-reactive Protein to Albumin Ratio for Sarcoma: A System Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-14 ◽  
Author(s):  
Erhu Fang ◽  
Xiaolin Wang ◽  
Jiexiong Feng ◽  
Xiang Zhao
Keyword(s):  
Fixed Effects ◽  
Meta Analysis ◽  
Prognostic Score ◽  
Glasgow Prognostic Score ◽  
Fixed Effects Model ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Albumin Ratio ◽  
Reactive Protein

Backgrounds. Both pretreatment serum CRP (C-reactive protein) level and ALB (albumin) level have been found to be predictive of survival for multiple malignancies including sarcoma. Since both of the GPS (Glasgow prognostic score) and CAR (C-reactive protein to albumin ratio) are based on the combination of CRP and ALB, we conducted a meta-analysis to evaluate the prognostic role of these two parameters for sarcoma patients. Methods. A detailed literature search was conducted in MEDLINE, Embase, and Cochrane Library for relevant research publications written in English. Patients’ clinical characteristics, outcomes of overall survival (OS), disease-specific survival (DSS), and disease-free survival (DFS) were extracted. Pooled hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) were combined to evaluate the prognostic role of GPS or CAR. Results. Twelve articles containing 2695 patients were identified as eligible studies. The results showed that an elevated GPS was significantly correlated with poor OS (HR=2.42; 95% CI: 1.98-2.94; p<0.001; fixed-effects model), DSS (HR=2.28; 95% CI: 1.75-2.97; p<0.001; fixed-effects model), and DFS (HR=2.05; 95% CI: 1.62-2.60; p<0.001; fixed-effects model). A higher CAR also was shown to be significantly correlated with poor OS (HR=2.23; 95% CI: 1.70-2.92; p<0.001; fixed-effects model) and DFS (HR=1.81; 95% CI: 1.7-2.58; p=0.001; fixed-effects model). Conclusion. An elevated GPS is predictive of poor survival in patients with sarcomas and is promising to be used as a factor for risk stratification. A higher CAR value is also predictive of poor survival; however, the optimal CAR cut-off value is still to be determined.

Prognostic Role of Admission C-Reactive Protein Level as a Predictor of In-Hospital Mortality in Type-A Acute Aortic Dissection: A Meta-Analysis

2019 ◽  
Vol 53 (7) ◽  
pp. 547-557 ◽  
Author(s):  
Wan Chin Hsieh ◽  
Brandon Michael Henry ◽  
Chong Chao Hsieh ◽  
Pavel Maruna ◽  
Mohamed Omara ◽  
...  
Keyword(s):  
Aortic Dissection ◽  
Hospital Mortality ◽  
Acute Aortic Dissection ◽  
Meta Analysis ◽  
Type A ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein ◽  
Increased Risk

Background: Acute aortic dissection (AD) is a lethal vascular disease, accounting for over 90% cases of acute aortic syndrome. Despite advances in understanding associated risk factors, the long-term prognosis for AD patients is still poor. Several prognostic biomarkers have been used for AD as per the IRAD, such as older age (>70 years), onset of chest pain and hypotension, but they are not effective in all patients. Instead, C-reactive protein (CRP) is a consistent inflammatory marker. CRP levels are abnormally increased in AD. However, the prognostic value of serum CRP level in AD remains unclear. Objective: To perform a systematic review and meta-analysis (registration no CRD42017056205) to evaluate whether CRP is a biomarker associated with in-hospital mortality in type-A AD. Methods: PubMed, Web of Science, CNKI, SciELO, and EMBASE were searched for papers published from January 2000 to October 2017 for studies on the prognostic role of CRP at admission in type-A AD patients. Outcome data were extracted and pooled hazard ratios (HRs) were calculated. Results: 18 (N = 2875 patients) studies met the inclusion criteria. Elevated CRP level was associated with a significantly increased risk of in-hospital mortality in patients with type-A AD (HR = 1.15, 95% CI: 1.06-1.25, p = 0.001). The pooled sensitivity of CRP in type-A AD patients was 77% (95% CI 69%–84%, p < 0.001), and the specificity was 72% (95% CI 66%–78%, p < 0.001). Conclusion: Elevated CRP level is significantly associated with increased risks of in-hospital mortality in patients with type-A AD. CRP is a convenient prognostic factor in type-A AD patients.

Prognostic role of C-reactive protein and Interleukin-6 in dialysis patients: a systematic review and meta-analysis

2012 ◽  
Vol 26 (2) ◽  
pp. 243-253 ◽  
Author(s):  
Wei Zhang ◽  
Jing He ◽  
Fengmei Zhang ◽  
Chengjin Huang ◽  
Ying Wu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Interleukin 6 ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Dialysis Patients ◽  
Prognostic Role ◽  
Reactive Protein

scholarly journals Prognostic Role of C-Reactive Protein in Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

2013 ◽  
Vol 10 (6) ◽  
pp. 653-664 ◽  
Author(s):  
Zhiyun Zheng ◽  
Lin Zhou ◽  
Sheng Gao ◽  
Zhe Yang ◽  
Jia yao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein
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