Prognostic role of C-reactive protein and Interleukin-6 in dialysis patients: a systematic review and meta-analysis

2012 ◽  
Vol 26 (2) ◽  
pp. 243-253 ◽  
Author(s):  
Wei Zhang ◽  
Jing He ◽  
Fengmei Zhang ◽  
Chengjin Huang ◽  
Ying Wu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Interleukin 6 ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Dialysis Patients ◽  
Prognostic Role ◽  
Reactive Protein

scholarly journals Prognostic role of C-reactive protein in prostate cancer: a systematic review and meta-analysis

2014 ◽  
Vol 16 (3) ◽  
pp. 467 ◽  
Author(s):  
Qing Xu ◽  
Yi-Jing Chen ◽  
Zhu-Qing Liu ◽  
Li Chu ◽  
Jue-Min Fang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Systematic Review ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein

scholarly journals Prognostic Role of C-Reactive Protein in Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis

2013 ◽  
Vol 10 (6) ◽  
pp. 653-664 ◽  
Author(s):  
Zhiyun Zheng ◽  
Lin Zhou ◽  
Sheng Gao ◽  
Zhe Yang ◽  
Jia yao ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Systematic Review ◽  
Meta Analysis ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein

scholarly journals Interleukin-6, C-reactive protein, fibrinogen, and risk of recurrence after ischaemic stroke: Systematic review and meta-analysis

2021 ◽  
pp. 239698732098400
Author(s):  
JJ McCabe ◽  
E O’Reilly ◽  
S Coveney ◽  
R Collins ◽  
L Healy ◽  
...  
Keyword(s):  
Systematic Review ◽  
Random Effects ◽  
Interleukin 6 ◽  
Inflammatory Markers ◽  
Recurrent Stroke ◽  
Meta Analysis ◽  
Randomised Trials ◽  
C Reactive Protein ◽  
Vascular Events ◽  
Reactive Protein

Background Recent randomised trials showed benefit for anti-inflammatory therapies in coronary disease but excluded stroke. The prognostic value of blood inflammatory markers after stroke is uncertain and guidelines do not recommend their routine measurement for risk stratification. Methods We performed a systematic review and meta-analysis of studies investigating the association of C-reactive protein (CRP), interleukin-6 (IL-6) and fibrinogen and risk of recurrent stroke or major vascular events (MVEs). We searched EMBASE and Ovid Medline until 10/1/19. Random-effects meta-analysis was performed for studies reporting comparable effect measures. Results Of 2,515 reports identified, 39 met eligibility criteria (IL-6, n = 10; CRP, n = 33; fibrinogen, n = 16). An association with recurrent stroke was reported in 12/26 studies (CRP), 2/11 (fibrinogen) and 3/6 (IL-6). On random-effects meta-analysis of comparable studies, CRP was associated with an increased risk of recurrent stroke [pooled hazard ratio (HR) per 1 standard-deviation (SD) increase in loge-CRP (1.14, 95% CI 1.06–1.22, p < 0.01)] and MVEs (pooled HR 1.21, CI 1.10–1.34, p < 0.01). Fibrinogen was also associated with recurrent stroke (HR 1.26, CI 1.07–1.47, p < 0.01) and MVEs (HR 1.31, 95% CI 1.15–1.49, p < 0.01). Trends were identified for IL-6 for recurrent stroke (HR per 1-SD increase 1.17, CI 0.97–1.41, p = 0.10) and MVEs (HR 1.22, CI 0.96–1.55, p = 0.10). Conclusion Despite evidence suggesting an association between inflammatory markers and post-stroke vascular recurrence, substantial methodological heterogeneity was apparent between studies. Individual-patient pooled analysis and standardisation of methods are needed to determine the prognostic role of blood inflammatory markers and to improve patient selection for randomised trials of inflammatory therapies.

scholarly journals Prognostic Role of C-Reactive Protein In Urological Cancers: A Meta-Analysis

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Liang Zhou ◽  
Xiang Cai ◽  
Qiang Liu ◽  
Zhong-Yu Jian ◽  
Hong Li ◽  
...  
Keyword(s):  
Meta Analysis ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Reactive Protein ◽  
Urological Cancers
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