scholarly journals A new approach for highly accurate, remote temperature probing using magnetic nanoparticles

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Jing Zhong ◽  
Wenzhong Liu ◽  
Li Kong ◽  
Paulo Cesar Morais
Keyword(s):  
Magnetic Nanoparticles ◽  
New Approach

A new approach for bioassays based on frequency- and time-domain measurements of magnetic nanoparticles

2010 ◽  
Vol 25 (5) ◽  
pp. 1008-1013 ◽  
Author(s):  
Fredrik Öisjöen ◽  
Justin F. Schneiderman ◽  
Andrea Prieto Astalan ◽  
Alexey Kalabukhov ◽  
Christer Johansson ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Time Domain ◽  
New Approach

New approach for understanding experimental NMR relaxivity properties of magnetic nanoparticles: focus on cobalt ferrite

2016 ◽  
Vol 18 (48) ◽  
pp. 32981-32991 ◽  
Author(s):  
Anne-Laure Rollet ◽  
Sophie Neveu ◽  
Patrice Porion ◽  
Vincent Dupuis ◽  
Nadine Cherrak ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Cobalt Ferrite ◽  
Nmr Relaxation ◽  
New Approach

Relaxivities r1 and r2 of cobalt ferrite magnetic nanoparticles (MNPs) have been investigated in the aim of improving the models of NMR relaxation induced by magnetic nanoparticles.

scholarly journals Magnetic nanoparticles as a new approach to improve the efficacy of gene therapy against differentiated human uterine fibroid cells and tumor-initiating stem cells

2016 ◽  
Vol 105 (6) ◽  
pp. 1638-1648.e8 ◽  
Author(s):  
Shahinaz Mahmood Shalaby ◽  
Mostafa K. Khater ◽  
Aymara Mas Perucho ◽  
Sara A. Mohamed ◽  
Inas Helwa ◽  
...  
Keyword(s):  
Stem Cells ◽  
Gene Therapy ◽  
Magnetic Nanoparticles ◽  
Uterine Fibroid ◽  
New Approach

scholarly journals A Smart Hyperthermia Nanofiber-Platform-Enabled Sustained Release of Doxorubicin and 17AAG for Synergistic Cancer Therapy

2021 ◽  
Vol 22 (5) ◽  
pp. 2542
Author(s):  
Lili Chen ◽  
Nanami Fujisawa ◽  
Masato Takanohashi ◽  
Mazaya Najmina ◽  
Koichiro Uto ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Cancer Therapy ◽  
Magnetic Composite ◽  
Therapeutic Effects ◽  
Protein Activity ◽  
New Approach ◽  
Molecularly Targeted Therapy ◽  
Medication Delivery ◽  
Composite Nanofiber ◽  
Biodegradable Poly

This study demonstrates the rational fabrication of a magnetic composite nanofiber mesh that can achieve mutual synergy of hyperthermia, chemotherapy, and thermo-molecularly targeted therapy for highly potent therapeutic effects. The nanofiber is composed of biodegradable poly(ε-caprolactone) with doxorubicin, magnetic nanoparticles, and 17-allylamino-17-demethoxygeldanamycin. The nanofiber exhibits distinct hyperthermia, owing to the presence of magnetic nanoparticles upon exposure of the mesh to an alternating magnetic field, which causes heat-induced cell killing as well as enhanced chemotherapeutic efficiency of doxorubicin. The effectiveness of hyperthermia is further enhanced through the inhibition of heat shock protein activity after hyperthermia by releasing the inhibitor 17-allylamino-17-demethoxygeldanamycin. These findings represent a smart nanofiber system for potent cancer therapy and may provide a new approach for the development of localized medication delivery.

RF heating of magnetic nanoparticles improves the thawing of cryopreserved biomaterials

TECHNOLOGY ◽  
2014 ◽  
Vol 02 (03) ◽  
pp. 229-242 ◽  
Author(s):  
Michael L. Etheridge ◽  
Yi Xu ◽  
Leoni Rott ◽  
Jeunghwan Choi ◽  
Birgit Glasmacher ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Great Promise ◽  
Rf Heating ◽  
Practical Application ◽  
Micro Computed Tomography ◽  
Heating Rates ◽  
Scanning Calorimetry ◽  
New Approach ◽  
Minimal Impact ◽  
Quality Control Tool

While vitrified cryopreservation holds great promise, practical application has been limited to smaller systems (cells and thin tissues) due to diffusive heat and mass transfer limitations, which are typically manifested as devitrification and cracking failures during thaw. Here then we describe a new approach for rapidly and uniformly heating cryopreserved biospecimens with radiofrequency (RF) excited magnetic nanoparticles (mNPs). Importantly, heating rates can be increased several fold over conventional boundary heating techniques and are independent of sample size. Initial differential scanning calorimetry studies indicate that the addition of the mNPs has minimal impact on the freeze-thaw behavior of the cryoprotectant systems themselves. Then proof-of-principle experiments in aqueous and cryoprotectant solutions demonstrate the ability to heat at rates high enough to mitigate or eliminate devitrification (hundreds of °C/min) and scaled heat transfer modeling is used to illustrate the potential of this innovative approach. Finally, X-ray micro-computed-tomography (micro-CT) is investigated as a planning and quality control tool, where the density-based measurements are able to quantify changes in cryoprotectant concentration, mNP concentration, and the frozen state (i.e. crystallized versus vitrified).

scholarly journals Investigations into the Biocompatibility of Nanohydroxyapatite Coated Magnetic Nanoparticles under Magnetic Situation

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Qing Li ◽  
Gang Zhou ◽  
Tong Wang ◽  
Yongzhao Hou ◽  
Xuliang Deng ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Magnetic Particles ◽  
X Ray Diffraction ◽  
New Approach ◽  
X Ray ◽  
In Vitro Experiment ◽  
Transmission Electron ◽  
Mesenchyme Stem Cells

Regenerative medicine consisting of cells and materials offers a new approach for repairing and regenerating the organs and tissues. More and more researches focused on the magnetic nanobiomaterials due to its superior advantages to traditional materials. However, the toxicity of nanosized magnetic particles cannot be ignored, especially under the magnetic situation. This study aims to study the biocompatibility of nanohydroxyapatite (n-HA-) coated magnetic nanoparticles under the magnetic situation. n-HA-coated magnetic nanoparticles were fabricated through an ultrasound-assisted coprecipitation method. Subsequently, these materials were analyzed by transmission electron microscope (TEM) and X-ray diffraction (XRD) and then were cultured with mesenchyme stem cells derived from human bone marrow (hMSC-BM). In vitro experiment proved the satisfactory biocompatibility of n-HA-coated magnetic nanoparticles. These important factors (ALP, OCN, and OPN) influence the osteogenic differentiation of hMSC-BM. It was found that the hMSC-BM with combination of n-HA/Fe3O4and magnetic stimulation presented higher degree of osteoblast-related markers than that in each alone. This research demonstrated that a novel nanohydroxyapatite coated magnetic nanoparticle is safe under the magnetic situation. Therefore, these n-HA-coated magnetic nanoparticles are promising biomagnetic materials for future applications.

scholarly journals Boron Drug Delivery via Encapsulated Magnetic Nanocomposites: A New Approach for BNCT in Cancer Treatment

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Yinghuai Zhu ◽  
Yongxiang Lin ◽  
Yi Zhun Zhu ◽  
Jia Lu ◽  
John A. Maguire ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Boron Concentration ◽  
Magnetic Nanocomposites ◽  
New Approach ◽  
Normal Tissues ◽  
High Boron ◽  
Loading Amount ◽  
Modified Magnetic Nanoparticles

Ortho-carborane cages have been successfully attached to modified magnetic nanoparticles via catalytic azide-alkyne cycloadditions between 1-R-2-butyl-Ortho-C2B10H10(R=Me,3;Ph,4)and propargyl group-enriched magnetic nanoparticles. A loading amount of 9.83 mmol boron atom/g starch-matrixed magnetic nanoparticles has been reached. The resulting nanocomposites have been found to be highly tumor-targeted vehicles under the influence of an external magnetic field (1.14T), yielding a high boron concentration of 51.4 μg/g tumor and ratios of around 10 : 1 tumor to normal tissues.

Enzymatic conversion of magnetic nanoparticles to a non-magnetic precipitate: a new approach to magnetic sensing

The Analyst ◽  
2016 ◽  
Vol 141 (18) ◽  
pp. 5246-5251 ◽  
Author(s):  
Arati G. Kolhatkar ◽  
Andrew C. Jamison ◽  
Ivan Nekrashevich ◽  
Katerina Kourentzi ◽  
Dmitri Litvinov ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Enzymatic Conversion ◽  
Magnetic Sensing ◽  
New Approach ◽  
Enzymatic Transformation

Magnetic sensing utilizes loss of signal via enzymatic transformation of magnetic nanoparticles (MNPs).

Sign in / Sign up

Export Citation Format

Share Document