scholarly journals In vivo pH monitoring using boron doped diamond microelectrode and silver needles: Application to stomach disorder diagnosis

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Stéphane Fierro ◽  
Ryo Seishima ◽  
Osamu Nagano ◽  
Hideyuki Saya ◽  
Yasuaki Einaga
2018 ◽  
Vol 11 (1) ◽  
pp. 463-484 ◽  
Author(s):  
Samuel J. Cobb ◽  
Zoe J. Ayres ◽  
Julie V. Macpherson

Boron doped diamond (BDD) is continuing to find numerous electrochemical applications across a diverse range of fields due to its unique properties, such as having a wide solvent window, low capacitance, and reduced resistance to fouling and mechanical robustness. In this review, we showcase the latest developments in the BDD electrochemical field. These are driven by a greater understanding of the relationship between material (surface) properties, required electrochemical performance, and improvements in synthetic growth/fabrication procedures, including material postprocessing. This has resulted in the production of BDD structures with the required function and geometry for the application of interest, making BDD a truly designer material. Current research areas range from in vivo bioelectrochemistry and neuronal/retinal stimulation to improved electroanalysis, advanced oxidation processes, supercapacitors, and the development of hybrid electrochemical-spectroscopic- and temperature-based technology aimed at enhancing electrochemical performance and understanding.


2020 ◽  
Vol 92 (20) ◽  
pp. 13742-13749
Author(s):  
Ai Hanawa ◽  
Genki Ogata ◽  
Seishiro Sawamura ◽  
Kai Asai ◽  
Sho Kanzaki ◽  
...  

Micromachines ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 128
Author(s):  
Erin Purcell ◽  
Michael Becker ◽  
Yue Guo ◽  
Seth Hara ◽  
Kip Ludwig ◽  
...  

Carbon-based electrodes combined with fast-scan cyclic voltammetry (FSCV) enable neurochemical sensing with high spatiotemporal resolution and sensitivity. While their attractive electrochemical and conductive properties have established a long history of use in the detection of neurotransmitters both in vitro and in vivo, carbon fiber microelectrodes (CFMEs) also have limitations in their fabrication, flexibility, and chronic stability. Diamond is a form of carbon with a more rigid bonding structure (sp3-hybridized) which can become conductive when boron-doped. Boron-doped diamond (BDD) is characterized by an extremely wide potential window, low background current, and good biocompatibility. Additionally, methods for processing and patterning diamond allow for high-throughput batch fabrication and customization of electrode arrays with unique architectures. While tradeoffs in sensitivity can undermine the advantages of BDD as a neurochemical sensor, there are numerous untapped opportunities to further improve performance, including anodic pretreatment, or optimization of the FSCV waveform, instrumentation, sp2/sp3 character, doping, surface characteristics, and signal processing. Here, we review the state-of-the-art in diamond electrodes for neurochemical sensing and discuss potential opportunities for future advancements of the technology. We highlight our team’s progress with the development of an all-diamond fiber ultramicroelectrode as a novel approach to advance the performance and applications of diamond-based neurochemical sensors.


2012 ◽  
Vol 2 (1) ◽  
Author(s):  
Stéphane Fierro ◽  
Momoko Yoshikawa ◽  
Osamu Nagano ◽  
Kenji Yoshimi ◽  
Hideyuki Saya ◽  
...  

2014 ◽  
Vol 172 ◽  
pp. 47-59 ◽  
Author(s):  
C. Hébert ◽  
E. Scorsone ◽  
A. Bendali ◽  
R. Kiran ◽  
M. Cottance ◽  
...  

Boron doped nanocrystalline diamond is known as a remarkable material for the fabrication of sensors, taking advantage of its biocompatibility, electrochemical properties, and stability. Sensors can be fabricated to directly probe physiological species from biofluids (e.g. blood or urine), as will be presented. In collaboration with electrophysiologists and biologists, the technology was adapted to enable structured diamond devices such as microelectrode arrays (MEAs), i.e. common electrophysiology tools, to probe neuronal activity distributed over large populations of neurons or embryonic organs. Specific MEAs can also be used to build neural prostheses or implants to compensate function losses due to lesions or degeneration of parts of the central nervous system, such as retinal implants, which exhibit real promise as biocompatible neuroprostheses for in vivo neuronal stimulations. New electrode geometries enable high performance electrodes to surpass more conventional materials for such applications.


2007 ◽  
Vol 79 (22) ◽  
pp. 8608-8615 ◽  
Author(s):  
Akane Suzuki ◽  
Tribidasari A. Ivandini ◽  
Kenji Yoshimi ◽  
Akira Fujishima ◽  
Genko Oyama ◽  
...  

2003 ◽  
Vol 764 ◽  
Author(s):  
Hiroyuki Togawa ◽  
Hideki Ichinose

AbstractAtomic resolution high-voltage transmission electron microscopy and electron energy loss spectroscopy were performed on grain boundaries of boron-doped diamond, cooperated with the ab-initio calculation. Segregated boron in the {112}∑3 boundary was caught by the EELS spectra. The change in atomic structure of the segregated boundary was successfully observed from the image by ARHVTEM. Based on the ARHVTEM image, a segregted structure model was proposed.


2015 ◽  
Vol 14 (6) ◽  
pp. 1339-1345
Author(s):  
Monica Ihos ◽  
Florica Manea ◽  
Maria Jitaru ◽  
Corneliu Bogatu ◽  
Rodica Pode

Processes ◽  
2020 ◽  
Vol 8 (6) ◽  
pp. 666 ◽  
Author(s):  
Nikolay Ivanovich Polushin ◽  
Alexander Ivanovich Laptev ◽  
Boris Vladimirovich Spitsyn ◽  
Alexander Evgenievich Alexenko ◽  
Alexander Mihailovich Polyansky ◽  
...  

Boron-doped diamond is a promising semiconductor material that can be used as a sensor and in power electronics. Currently, researchers have obtained thin boron-doped diamond layers due to low film growth rates (2–10 μm/h), with polycrystalline diamond growth on the front and edge planes of thicker crystals, inhomogeneous properties in the growing crystal’s volume, and the presence of different structural defects. One way to reduce structural imperfection is the specification of optimal synthesis conditions, as well as surface etching, to remove diamond polycrystals. Etching can be carried out using various gas compositions, but this operation is conducted with the interruption of the diamond deposition process; therefore, inhomogeneity in the diamond structure appears. The solution to this problem is etching in the process of diamond deposition. To realize this in the present work, we used triethyl borate as a boron-containing substance in the process of boron-doped diamond chemical vapor deposition. Due to the oxygen atoms in the triethyl borate molecule, it became possible to carry out an experiment on simultaneous boron-doped diamond deposition and growing surface etching without the requirement of process interruption for other operations. As a result of the experiments, we obtain highly boron-doped monocrystalline diamond layers with a thickness of about 8 μm and a boron content of 2.9%. Defects in the form of diamond polycrystals were not detected on the surface and around the periphery of the plate.


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