scholarly journals In vivo assessment of cancerous tumors using boron doped diamond microelectrode

2012 ◽  
Vol 2 (1) ◽  
Author(s):  
Stéphane Fierro ◽  
Momoko Yoshikawa ◽  
Osamu Nagano ◽  
Kenji Yoshimi ◽  
Hideyuki Saya ◽  
...  
Keyword(s):  
Boron Doped Diamond ◽  
Boron Doped ◽  
In Vivo Assessment

Boron Doped Diamond: A Designer Electrode Material for the Twenty-First Century

2018 ◽  
Vol 11 (1) ◽  
pp. 463-484 ◽  
Author(s):  
Samuel J. Cobb ◽  
Zoe J. Ayres ◽  
Julie V. Macpherson
Keyword(s):  
Electrochemical Performance ◽  
First Century ◽  
Material Surface ◽  
Boron Doped Diamond ◽  
Diverse Range ◽  
Research Areas ◽  
Retinal Stimulation ◽  
Boron Doped ◽  
The Relationship

Boron doped diamond (BDD) is continuing to find numerous electrochemical applications across a diverse range of fields due to its unique properties, such as having a wide solvent window, low capacitance, and reduced resistance to fouling and mechanical robustness. In this review, we showcase the latest developments in the BDD electrochemical field. These are driven by a greater understanding of the relationship between material (surface) properties, required electrochemical performance, and improvements in synthetic growth/fabrication procedures, including material postprocessing. This has resulted in the production of BDD structures with the required function and geometry for the application of interest, making BDD a truly designer material. Current research areas range from in vivo bioelectrochemistry and neuronal/retinal stimulation to improved electroanalysis, advanced oxidation processes, supercapacitors, and the development of hybrid electrochemical-spectroscopic- and temperature-based technology aimed at enhancing electrochemical performance and understanding.

In Vivo Real-Time Simultaneous Examination of Drug Kinetics at Two Separate Locations Using Boron-Doped Diamond Microelectrodes

2020 ◽  
Vol 92 (20) ◽  
pp. 13742-13749
Author(s):  
Ai Hanawa ◽  
Genki Ogata ◽  
Seishiro Sawamura ◽  
Kai Asai ◽  
Sho Kanzaki ◽  
...  
Keyword(s):  
Real Time ◽  
Boron Doped Diamond ◽  
Boron Doped ◽  
Drug Kinetics

scholarly journals In vivo pH monitoring using boron doped diamond microelectrode and silver needles: Application to stomach disorder diagnosis

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Stéphane Fierro ◽  
Ryo Seishima ◽  
Osamu Nagano ◽  
Hideyuki Saya ◽  
Yasuaki Einaga
Keyword(s):  
Ph Monitoring ◽  
Boron Doped Diamond ◽  
Boron Doped ◽  
Stomach Disorder

scholarly journals Next-Generation Diamond Electrodes for Neurochemical Sensing: Challenges and Opportunities

Micromachines ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 128
Author(s):  
Erin Purcell ◽  
Michael Becker ◽  
Yue Guo ◽  
Seth Hara ◽  
Kip Ludwig ◽  
...  
Keyword(s):  
Surface Characteristics ◽  
Electrode Arrays ◽  
Diamond Electrodes ◽  
Boron Doped Diamond ◽  
Spatiotemporal Resolution ◽  
Bonding Structure ◽  
Boron Doped ◽  
Novel Approach

Carbon-based electrodes combined with fast-scan cyclic voltammetry (FSCV) enable neurochemical sensing with high spatiotemporal resolution and sensitivity. While their attractive electrochemical and conductive properties have established a long history of use in the detection of neurotransmitters both in vitro and in vivo, carbon fiber microelectrodes (CFMEs) also have limitations in their fabrication, flexibility, and chronic stability. Diamond is a form of carbon with a more rigid bonding structure (sp3-hybridized) which can become conductive when boron-doped. Boron-doped diamond (BDD) is characterized by an extremely wide potential window, low background current, and good biocompatibility. Additionally, methods for processing and patterning diamond allow for high-throughput batch fabrication and customization of electrode arrays with unique architectures. While tradeoffs in sensitivity can undermine the advantages of BDD as a neurochemical sensor, there are numerous untapped opportunities to further improve performance, including anodic pretreatment, or optimization of the FSCV waveform, instrumentation, sp2/sp3 character, doping, surface characteristics, and signal processing. Here, we review the state-of-the-art in diamond electrodes for neurochemical sensing and discuss potential opportunities for future advancements of the technology. We highlight our team’s progress with the development of an all-diamond fiber ultramicroelectrode as a novel approach to advance the performance and applications of diamond-based neurochemical sensors.

scholarly journals Boron doped diamond biotechnology: from sensors to neurointerfaces

2014 ◽  
Vol 172 ◽  
pp. 47-59 ◽  
Author(s):  
C. Hébert ◽  
E. Scorsone ◽  
A. Bendali ◽  
R. Kiran ◽  
M. Cottance ◽  
...  
Keyword(s):  
Central Nervous System ◽  
High Performance ◽  
Microelectrode Arrays ◽  
Neural Prostheses ◽  
Boron Doped Diamond ◽  
Boron Doped ◽  
Retinal Implants ◽  
Large Populations ◽  
The Central Nervous System

Boron doped nanocrystalline diamond is known as a remarkable material for the fabrication of sensors, taking advantage of its biocompatibility, electrochemical properties, and stability. Sensors can be fabricated to directly probe physiological species from biofluids (e.g. blood or urine), as will be presented. In collaboration with electrophysiologists and biologists, the technology was adapted to enable structured diamond devices such as microelectrode arrays (MEAs), i.e. common electrophysiology tools, to probe neuronal activity distributed over large populations of neurons or embryonic organs. Specific MEAs can also be used to build neural prostheses or implants to compensate function losses due to lesions or degeneration of parts of the central nervous system, such as retinal implants, which exhibit real promise as biocompatible neuroprostheses for in vivo neuronal stimulations. New electrode geometries enable high performance electrodes to surpass more conventional materials for such applications.

Fabrication, Characterization, and Application of Boron-Doped Diamond Microelectrodes for in Vivo Dopamine Detection

2007 ◽  
Vol 79 (22) ◽  
pp. 8608-8615 ◽  
Author(s):  
Akane Suzuki ◽  
Tribidasari A. Ivandini ◽  
Kenji Yoshimi ◽  
Akira Fujishima ◽  
Genko Oyama ◽  
...  
Keyword(s):  
Boron Doped Diamond ◽  
Dopamine Detection ◽  
Boron Doped

In Vivo Assessment of Synovial Microcirculation and Leukocyte–Endothelial Cell Interaction in Mouse Antigen-Induced Arthritis

1999 ◽  
Vol 6 (4) ◽  
pp. 281-290 ◽  
Author(s):  
A N D R E A S VEIHELMANN ◽  
ANTHONY G U S T A V E HARRIS ◽  
F R I T Z KROMBACH ◽  
E L K E SCHÜTZE ◽  
HANS JÜRGEN REFIOR ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Cell Interaction ◽  
Endothelial Cell Interaction ◽  
In Vivo Assessment

In vivo assessment of anti-CD34 coated ePTFE vascular prostheses

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
W Mrowczynski ◽  
A Rungatscher ◽  
F Buchegger ◽  
JC Tille ◽  
D Mugnai ◽  
...  
Keyword(s):  
Vascular Prostheses ◽  
In Vivo Assessment
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