scholarly journals Relative Hypoadiponectinemia, Insulin Resistance, and Increased Visceral Fat in Euthyroid Prepubertal Girls With Low-Normal Serum Free Thyroxine

Obesity ◽  
2012 ◽  
Vol 20 (7) ◽  
pp. 1455-1461 ◽  
Author(s):  
Anna Prats-Puig ◽  
Carme Sitjar ◽  
Rosa Ribot ◽  
Mar Calvo ◽  
Núria Clausell-Pomés ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Visceral Fat ◽  
Normal Serum ◽  
Free Thyroxine ◽  
Serum Free ◽  
Prepubertal Girls ◽  
Serum Free Thyroxine

scholarly journals Misleading results from immunoassays of serum free thyroxine in the presence of rheumatoid factor

1997 ◽  
Vol 43 (6) ◽  
pp. 957-962 ◽  
Author(s):  
Anthony G W Norden ◽  
Rodwin A Jackson ◽  
Lorraine E Norden ◽  
A Jane Griffin ◽  
Margaret A Barnes ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Rheumatoid Factor ◽  
Equilibrium Dialysis ◽  
Thyroid Stimulating Hormone ◽  
Normal Serum ◽  
Free Thyroxine ◽  
Free Triiodothyronine ◽  
Serum Free ◽  
Serum Free Thyroxine ◽  
Stimulating Hormone

Abstract A novel interference with measurements of serum free thyroxine (FT4) caused by rheumatoid factor (RhF) is described. We found misleading, sometimes gross, increases of FT4 results in 5 clinically euthyroid elderly female patients with high RhF concentrations. All 5 patients had high FT4 on Abbott AxSYM® or IMx® analyzers. “NETRIA” immunoassays gave misleading results in 4 of the 5 patients; Amerlex-MAB® in 2 of 4 patients; AutoDELFIA®in 2 of the 5; and Corning ACS-180® and Bayer Diagnostics Immuno 1® in 1 of the 5. BM-ES700® system results for FT4 in these women remained within the reference range. Results for serum T4, thyroid-stimulating hormone, free triiodothyronine, thyroid-hormone-binding globulin, and FT4 measured by equilibrium dialysis were normal in all 5 patients. Drugs, albumin-binding variants, and anti-thyroid-hormone antibodies were excluded as interferences. Addition to normal serum of the RhF isolated from each of the 5 patients increased the apparent FT4 (Abbott AxSYM). Screening of 83 unselected patients demonstrated a highly significant positive correlation between FT4 (Abbott AxSYM) and RhF concentrations. Discrepant, apparently increased FT4 with a normal result for thyroid-stimulating hormone should lead to measurement of the patient’s RhF concentration.

Serum free thyroxine in patients with T3-toxicosis

1985 ◽  
Vol 110 (3) ◽  
pp. 354-359 ◽  
Author(s):  
Enio Martino ◽  
Alessandro Pacchiarotti ◽  
Fabrizio Aghini-Lombardi ◽  
Lucia Grasso ◽  
Giovanni Bambini ◽  
...  
Keyword(s):  
Clinical Evidence ◽  
Elevated Serum ◽  
Normal Serum ◽  
Free Thyroxine ◽  
Total Serum ◽  
Free Triiodothyronine ◽  
Serum Free ◽  
Serum Thyroxine ◽  
Free Thyroxine Index ◽  
Serum Free Thyroxine

Abstract. The serum free thyroxine concentration was measured by direct radioimmunoassay in 38 untreated T3-thyrotoxic patients with elevated serum total and free triiodothyronine, normal serum thyroxine and free thyroxine index, no TSH response to TRH, and with clinical evidence of hyperthyroidism. An elevation of circulating free thyroxine values was observed in 58% of the patients, whereas total serum thyroxine concentration was within the normal range. It is suggested, therefore, that T3-thyrotoxicosis should be reserved for patients with elevated serum total T3 and free T3 concentrations and normal serum total T4 and free T4 concentrations. Serum thyroxine-binding globulin concentrations were significantly lower (P < 0.025) in patients with an elevated serum free thyroxine (18.7 ± 3.6 μg/ml: mean ± sd) as compared with those in patients with a normal free thyroxine concentration (23.4 ± 2.6 μg/ml). In addition, no daily fluctuations in total and free thyroxine concentration were observed in 6 patients over a 4–8 day period.

Factors Affecting the Serum Free Thyroxine Levels in Hospitalized Chronic Geriatric Patients

1993 ◽  
Vol 41 (7) ◽  
pp. 742-746 ◽  
Author(s):  
Istvan Szabolcs ◽  
Christoph Ploenes ◽  
Mathias Beyer ◽  
Wolfdieter Bernard ◽  
Jorg Herrmann
Keyword(s):  
Geriatric Patients ◽  
Free Thyroxine ◽  
Factors Affecting ◽  
Serum Free ◽  
Serum Free Thyroxine

scholarly journals Serum Free Thyroxine and Triiodothyronine Concentrations in Subacute Thyroiditis

1980 ◽  
Vol 56 (11) ◽  
pp. 1527-1534
Author(s):  
Katsumi YOSHIDA ◽  
Toshiro SAKURADA ◽  
Nobuko KAISE ◽  
Kazuo KAISE ◽  
Hirofumi KITAOKA ◽  
...  
Keyword(s):  
Free Thyroxine ◽  
Subacute Thyroiditis ◽  
Serum Free ◽  
Serum Free Thyroxine

scholarly journals Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients

2016 ◽  
Vol 63 (3) ◽  
pp. 221-229 ◽  
Author(s):  
Koshi Hashimoto ◽  
Tetsuya Tagami ◽  
Hajime Yamakage ◽  
Kazuya Muranaka ◽  
Masashi Tanaka ◽  
...  
Keyword(s):  
Weight Reduction ◽  
Free Thyroxine ◽  
Serum Free ◽  
Female Patients ◽  
Obese Female ◽  
Serum Free Thyroxine

Variations in Serum Free Thyroxine Concentration Within the Reference Range Predicts the Incidence of Metabolic Syndrome in Non-Obese Adults: A Cohort Study

Thyroid ◽  
2017 ◽  
Vol 27 (7) ◽  
pp. 886-893 ◽  
Author(s):  
Ladan Mehran ◽  
Atieh Amouzegar ◽  
Mahmood Bakhtiyari ◽  
Mohammad Ali Mansournia ◽  
Parnian Kheirkhah Rahimabad ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Reference Range ◽  
Free Thyroxine ◽  
Obese Adults ◽  
Serum Free ◽  
Serum Free Thyroxine
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