scholarly journals Impact of Variation in the FTO Gene on Whole Body Fat Distribution, Ectopic Fat, and Weight Loss

Obesity ◽  
2008 ◽  
Vol 16 (8) ◽  
pp. 1969-1972 ◽  
Author(s):  
Axel Haupt ◽  
Claus Thamer ◽  
Jürgen Machann ◽  
Kerstin Kirchhoff ◽  
Norbert Stefan ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Whole Body ◽  
Ectopic Fat ◽  
Fto Gene

scholarly journals Impact of Variation Near MC4R on Whole-body Fat Distribution, Liver Fat, and Weight Loss

Obesity ◽  
2009 ◽  
Vol 17 (10) ◽  
pp. 1942-1945 ◽  
Author(s):  
Axel Haupt ◽  
Claus Thamer ◽  
Martin Heni ◽  
Otto Tschritter ◽  
Jürgen Machann ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Liver Fat ◽  
Whole Body

scholarly journals Unacylated ghrelin is associated with changes in body composition and body fat distribution during long-term exercise intervention

2011 ◽  
Vol 165 (2) ◽  
pp. 243-248 ◽  
Author(s):  
Henna Cederberg ◽  
Ulla Rajala ◽  
Vesa-Matti Koivisto ◽  
Jari Jokelainen ◽  
Heljä-Marja Surcel ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Waist Circumference ◽  
Body Fat ◽  
Exercise Performance ◽  
Exercise Intervention ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Unacylated Ghrelin

ObjectiveGhrelin, a gut–brain peptide involved in energy homeostasis, circulates predominantly (>90%) in unacylated form. Previous studies, however, have focused on total and acylated ghrelin, and the role of unacylated ghrelin (UAG) is not well understood. Particularly, the association of UAG with weight loss and changes in body composition in adults remains unclear. We hypothesized that exercise-associated increase in UAG level is associated with weight loss, favorable changes in body composition, and body fat distribution.Design and methodsA prospective study of 552 young men (mean age 19.3 and range 19–28 years) undergoing military service with structured 6-month exercise training program. Exercise performance, body composition, and biochemical measurements were obtained at baseline and follow-up. Association between changes in UAG levels and body composition and body fat distribution were evaluated.ResultsAn increase in UAG level during the exercise intervention was associated with reduced weight, fat mass (FM), fat percentage (fat %), and waist circumference, but not with fat-free mass. Inverse associations of changes in UAG level with changes in waist circumference and fat % were independent of weight at baseline, and changes in weight and exercise performance. Associations of changes in UAG level with waist circumference were significantly stronger than with fat % after the adjustment for confounding variables.ConclusionUAG is associated with changes in body weight and body composition during an intensive long-term exercise intervention in young men. The association of UAG levels with changes in central obesity was stronger than with total FM.

Effect of weight loss on regional body fat distribution in premenopausal women

1993 ◽  
Vol 58 (1) ◽  
pp. 29-34 ◽  
Author(s):  
M Zamboni ◽  
F Armellini ◽  
E Turcato ◽  
T Todesco ◽  
L Bissoli ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Fat ◽  
Premenopausal Women ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Regional Body Fat

Rapid Automated Measurement of Body Fat Distribution from Whole-Body MRI

2005 ◽  
Vol 185 (2) ◽  
pp. 418-423 ◽  
Author(s):  
Darren D. Brennan ◽  
Paul F. Whelan ◽  
Kevin Robinson ◽  
Ovidiu Ghita ◽  
Julie M. O'Brien ◽  
...  
Keyword(s):  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Whole Body ◽  
Automated Measurement ◽  
Whole Body Mri

46. Effects of weight loss versus drug therapy on blood pressure body fat distribution, insulin and glucose

1991 ◽  
Vol 9 (6) ◽  
pp. S441
Author(s):  
Bjorn Fagerberg ◽  
A. Berglund ◽  
Goran Berglund ◽  
Ove K. Andersson
Keyword(s):  
Blood Pressure ◽  
Weight Loss ◽  
Drug Therapy ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution

scholarly journals Associations of nicotine dependence and fat distribution in Chinese male adults: a cross-sectional study in Lanxi, China

BMJ Open ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. e022465
Author(s):  
Chen Wei ◽  
Sunyue Ye ◽  
Jessica Ruolin Sheng ◽  
Xiaoguang Ma ◽  
Yuan Ru ◽  
...  
Keyword(s):  
Nicotine Dependence ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Whole Body ◽  
Fat Percentage ◽  
Central Fat ◽  
Gynoid Fat ◽  
The Impact ◽  
Chinese Male

IntroductionPrevious studies have showed association between smoking and central fat distribution. However, the impact of smoking on whole body fat distribution, particularly peripheral fat distribution remains unclear.MethodsNicotine dependence was assessed in a total of 1264 male adults aged 18–80 years using the Fagerström Test for Nicotine Dependence (FTND). Smoking status was categorised as non-smokers, former and current smokers with very low, low/moderate, or high FTND scores. Body fat distribution was determined using the dual energy X-ray absorptiometry and anthropometric measurements. Multivariable linear regression models were applied to examine the adjusted associations between body fat distribution and smoking in all participants, and its association with FTND scores in the current smokers.ResultsGreater waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), trunk fat percentage (%TF), android fat percentage (%AF) and android-to-gynoid fat mass ratio (AOI); but lower legs fat percentage (%LegF), limb fat percentage (%LimbF) and gynoid fat percentage (%GF) were found in current smokers with high FTND scores compared with non-smokers. In current smokers aged 60 years or older, FTND scores had positive associations with WC, WHR, WHtR, %TF, %AF and AOI, and negative associations with %LegF, %LimbF and %GF.ConclusionsNicotine dependence was positively associated with central fat distribution and negatively associated with peripheral fat distribution in Chinese male adults, particularly in those older or heavy smokers, and these associations were independent from body mass index, which might be due to long exposure to smoking.

scholarly journals Phenotypic Heterogeneity in Body Fat Distribution in Patients with Congenital Generalized Lipodystrophy Caused by Mutations in the AGPAT2 or Seipin Genes

2003 ◽  
Vol 88 (11) ◽  
pp. 5433-5437 ◽  
Author(s):  
Vinaya Simha ◽  
Abhimanyu Garg
Keyword(s):  
Adipose Tissue ◽  
Body Fat ◽  
Autosomal Recessive ◽  
Acanthosis Nigricans ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Whole Body ◽  
Severe Insulin Resistance ◽  
Congenital Generalized Lipodystrophy ◽  
Chromosome 9Q34

Abstract Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive syndrome characterized by extreme paucity of adipose tissue since birth, acanthosis nigricans, severe insulin resistance, marked hypertriglyceridemia, and early-onset diabetes mellitus. Recently, we reported mutations in the 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2) gene in CGL pedigrees linked to chromosome 9q34 (CGL1 subtype), and mutations in the Seipin gene were reported in pedigrees linked to chromosome 11q13 (CGL2 subtype). Whether the two subtypes have differences in body fat distribution has not been investigated. We, therefore, compared whole-body adipose tissue distribution by magnetic resonance imaging in 10 CGL patients, of whom seven (six females, one male) had CGL1 and three (two males, one female) had CGL2. Both subtypes had marked lack of metabolically active adipose tissue located at most sc, intermuscular, bone marrow, intraabdominal, and intrathoracic regions. Paucity of mechanical adipose tissue in the palms, soles, orbits, scalp, and periarticular regions was noted in CGL2, whereas it was well preserved in CGL1 patients. We conclude that CGL patients with Seipin mutations have a more severe lack of body fat, which affects both metabolically active and mechanical adipose tissue, compared with patients with mutations in the AGPAT2 gene.

Sign in / Sign up

Export Citation Format

Share Document