Corticosteroid Binding Globulin Gene Polymorphism Influences Cortisol Driven Fat Distribution in Obese Women

2005 ◽  
Vol 13 (9) ◽  
pp. 1485-1490 ◽  
Author(s):  
Pascal Barat ◽  
Martine Duclos ◽  
Blandine Gatta ◽  
Patrick Roger ◽  
Pierre Mormede ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Fat Distribution ◽  
Obese Women ◽  
Corticosteroid Binding Globulin ◽  
Globulin Gene

SEX HORMONE BINDING GLOBULIN GENE POLYMORPHISM AND RISK OF TYPE2 DIABETES MELLITUS IN EGYPTIAN MEN

2014 ◽  
Vol 20 (2) ◽  
pp. 1-7
Author(s):  
Shereen El Tarhouny ◽  
Soha Zakaria ◽  
Khaled d Hadhoud ◽  
Manal Hanafi ◽  
Azza Kamel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gene Polymorphism ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Type2 Diabetes ◽  
Type2 Diabetes Mellitus ◽  
Globulin Gene

Interleukin-6 −174G/C gene polymorphism affects muscle damage response to acute eccentric resistance exercise in elderly obese women

2013 ◽  
Vol 48 (11) ◽  
pp. 1255-1259 ◽  
Author(s):  
Silvana Schwerz Funghetto ◽  
Jonato Prestes ◽  
Alessandro de Oliveira Silva ◽  
Darlan L. Farias ◽  
Tatiane G. Teixeira ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Resistance Exercise ◽  
Muscle Damage ◽  
Interleukin 6 ◽  
Obese Women ◽  
Damage Response

scholarly journals Influence of duration of menopause, anthropometric and hormonal parameters on metabolic syndrome

2010 ◽  
Vol 63 (1-2) ◽  
pp. 33-39 ◽  
Author(s):  
Aleksandra Simoncig-Netjasov ◽  
Svetlana Vujovic ◽  
Miomira Ivovic ◽  
Milina Tancic-Gajic ◽  
Milka Drezgic
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Diastolic Blood Pressure ◽  
Fasting Glucose ◽  
Fat Distribution ◽  
Normal Weight ◽  
Sex Hormone Binding Globulin ◽  
Control Group ◽  
Obese Women ◽  
Waist Hip Ratio

Introduction. Hypoestrogenic status in the menopausal women shows a shift to a central android fat distribution and metabolic syndrome (MS). Related metabolic changes and hypertension increase the risk for cardiovascular (CV) diseases. The aim of this study was to investigate the influence of duration of menopause, anthropometric and hormonal parameters on metabolic syndrome. Material and methods. 50 obese women were examined with BMI=31.92?5.83 kg/m2, age 54.40?3.64, time since menopause 5.90?5.46 years. Control group consisted of 37 normal weight women with BMI=23.50?2.13 kg/m2, age 53.92?3.95, time since menopause 5.96?4.92 years. Anthropometric characteristics and blood pressure were measured. Blood was taken at 8 am for: fasting glucose, triglycerides, cholesterol, HDL, LDL, apolipoprotein A (ApoA), apolipoprotein B (ApoB), lipoprotein(a) (Lp(a)), C-reactive protein (CRP), fibrinogen, FSH, LH, prolactin, estradiol, progesterone, testosterone and sex hormone binding globulin (SHBG). Results. In obese women significant negative correlations were found for: BMI and HDL (p<0,05), waist and HDL (p<0,05), FSH and systolic blood pressure (p<0.01), FSH and fasting glucose (p<0,05), LH and waist (p<0.05), SHBG and fasting glucose (p<0.05). A positive correlation was found for lime since meno?pause and waist/hip ratio (p<0.05). In controls positive correlations were found for: waist/hip ratio and systolic and diastolic blood pressure (p<0,05), LH and HDL (p<0.05), estradiol and diastolic blood pressure (p<0,05). Negative correlations were detected for estradiol and waist (p<0,05), time since menopause and HDL (p<0,05). Conclusion. Gaining weight together with menopausal endocrine changes cause metabolic and hemodynamic imbalances, which contribute to risk for cardiovascular diseases.

scholarly journals Inhibition of Corticosteroid-Binding Globulin Gene Expression by Glucocorticoids Involves C/EBPβ

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e110702 ◽  
Author(s):  
Nicolette Verhoog ◽  
Fatima Allie-Reid ◽  
Wim Vanden Berghe ◽  
Carine Smith ◽  
Guy Haegeman ◽  
...  
Keyword(s):  
Gene Expression ◽  
Corticosteroid Binding Globulin ◽  
Globulin Gene

Weight Cycling and Body Composition in Obese Women

1998 ◽  
Vol 7 (1) ◽  
pp. 1-12
Author(s):  
Roger L. Hammer ◽  
Daryl McCombs ◽  
A. Garth Fisher
Keyword(s):  
Weight Loss ◽  
Body Fat ◽  
Weight Control ◽  
Fat Distribution ◽  
Upper Body ◽  
Weight Cycling ◽  
Obese Women ◽  
Body Fatness ◽  
Low Fat Diet ◽  
Percentage Of Body Fat

It has been suggested that weight loss and regain, known as weight cycling, may result in greater body fatness and increased upper body fat distribution which may lead to adverse health consequences. These are concerns that may discourage some obese women from undergoing weight loss efforts. We retested 44 obese women, who took part in one of two weight control studies conducted in our laboratory, at either 6 or 12 months posttreatment. The followup study was performed to determine whether percent body fat and waist/hip ratio (WHR) had increased in those subjects who failed to maintain their weight loss. Subjects lost (mean + SD) 8.6 + 1.2 kg body weight, of which 7.0 + 1.0 kg was fat, and reduced their WHR by 0.03 + 0.006 (all p’s < .01) after either 12 or 16 weeks of treatment comprised of eating a low-fat diet, and in most cases performing endurance exercise training. At followup subjects were divided into groups based on the amount of weight regained. Those who regained (n=19) their lost weight were not fatter nor was their WHR higher than before the study began. These results do not support claims that weight cycling, in this case a single cycle, increases overall percentage of body fat or causes a redistribution of fat to the abdominal region of women.

scholarly journals 3.4 Fat Distribution and Cardiovascular Risk in Obese Women

2008 ◽  
Vol 15 (3) ◽  
pp. 194-194
Author(s):  
G. Salvetti ◽  
F. Santini ◽  
A. Pucci ◽  
D. Versari ◽  
A. Virdis ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Fat Distribution ◽  
Obese Women

Evidence for bone mass and body fat distribution relationship in postmenopausal obese women

1997 ◽  
Vol 24 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Brunetto Tarquini ◽  
Nadia Navari ◽  
Federico Perfetto ◽  
Adriano Piluso ◽  
Salvatore Romano ◽  
...  
Keyword(s):  
Bone Mass ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Obese Women

Impact of Menopause and Body Composition Status on Dyslipidemia in Women

2021 ◽  
Vol 45 (1) ◽  
pp. 71-80
Author(s):  
Joshua S. Wooten ◽  
Benjamin L. Webb ◽  
Nancy M. DiMarco ◽  
David L. Nichols ◽  
Charlotte F. Sanborn
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Menopausal Status ◽  
Premenopausal Women ◽  
Fat Distribution ◽  
Normal Weight ◽  
Obese Women ◽  
Age Related ◽  
Regional Body Composition ◽  
Lipids And Lipoproteins

Objective: The aim of this study was to identify the effects of menopausal and body composition statuses on measures of total and regional body composition and dyslipidemia in women. Methods: Sedentary, non-smoking women (N = 212), not currently treated for dyslipidemia were grouped based on 2 categories: (1) menstrual status: premenopausal or postmenopausal and (2) body composition status: normal weight (NW; BMI < 25 kg/m2 and body fat (BF) < 36%), normal weight obese (NWO; BMI < 25 kg/m2 and BF > 36%), or obese (BMI > 25 kg/m2 and BF > 36%), to determine differences in total and regional body composition and measures of lipid and lipoprotein-cholesterol concentrations. Results: Overall, a greater prevalence of NWO was observed in postmenopausal versus premenopausal women. Being postmenopausal was associated with higher TC, LDL-C, non-HDL-C, HDL-C, and HDL3-C. Premenopausal NWO women had elevated LDL-C and VLDL-C comparable to obese women. Postmenopausal NWO women had elevated Tg and VLDL-C and lower HDL-C similar to obese women. Conclusions: Menopausal status was not associated with differences in fat distribution, however, the age-related differences in lipids and lipoproteins appear to be due to a difference in menopausal status exacerbated in women who are NWO.

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