Mapping the common variation

2005 ◽  
Vol 6 (12) ◽  
pp. 874-874
Author(s):  
Magdalena Skipper
Keyword(s):  
Common Variation ◽  
The Common

scholarly journals Yet Another Statistical Analysis of Bob Ross Paintings

2016 ◽  
Author(s):  
Christopher Steven Marcum
Keyword(s):  
Statistical Analysis ◽  
Future Research ◽  
Common Variation ◽  
The Common ◽  
Shared Variance ◽  
First Time ◽  
Do So

In this paper, we analyze a sample of clippings from paintings by the lateartist Bob Ross.Previous work focused on the qualitative themes of his paintings (Hickey,2014); here, we expand on that line of research by considering thecolorspace and luminosity values as our data. Our results demonstrate thesubtle aesthetics of the average Ross painting, the common variation sharedby his paintings, and the structure of the relationships between eachpainting in our sample. We reveal, for the first time, renderings of theaverage paintings and introduce “eigenross” components to identify andevaluate shared variance. Additionally, all data and code are embedded inthis document to encourage future research, and, in the spirit of Bob Ross,to teach others how to do so.

scholarly journals A Common Variation in Deiodinase 1 Gene DIO1 Is Associated with the Relative Levels of Free Thyroxine and Triiodothyronine

2008 ◽  
Vol 93 (8) ◽  
pp. 3075-3081 ◽  
Author(s):  
Vijay Panicker ◽  
Christie Cluett ◽  
Beverley Shields ◽  
Anna Murray ◽  
Kirstie S. Parnell ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Thyroid Hormones ◽  
Common Genetic Variation ◽  
Free T4 ◽  
Total N ◽  
Hormone Levels ◽  
Free T3 ◽  
Common Variation ◽  
Wide Range ◽  
The Common

Abstract Introduction: Genetic factors influence circulating thyroid hormone levels, but the common gene variants involved have not been conclusively identified. The genes encoding the iodothyronine deiodinases are good candidates because they alter the balance of thyroid hormones. We aimed to thoroughly examine the role of common variation across the three deiodinase genes in relation to thyroid hormones. Methods: We used HapMap data to select single-nucleotide polymorphisms (SNPs) that captured a large proportion of the common genetic variation across the three deiodinase genes. We analyzed these initially in a cohort of 552 people on T4 replacement. Suggestive findings were taken forward into three additional studies in people not on T4 (total n = 2513) and metaanalyzed for confirmation. Results: A SNP in the DIO1 gene, rs2235544, was associated with the free T3 to free T4 ratio with genome-wide levels of significance (P = 3.6 × 10−13). The C-allele of this SNP was associated with increased deiodinase 1 (D1) function with resulting increase in free T3/T4 ratio and free T3 and decrease in free T4 and rT3. There was no effect on serum TSH levels. None of the SNPs in the genes coding for D2 or D3 had any influence on hormone levels. Conclusions: This study provides convincing evidence that common genetic variation in DIO1 alters deiodinase function, resulting in an alteration in the balance of circulating free T3 to free T4. This should prove a valuable tool to assess the relative effects of circulating free T3vs. free T4 on a wide range of biological parameters.

scholarly journals Microsurgical anatomy of the extracranial-extradural origin of the posterior inferior cerebellar artery

1999 ◽  
Vol 7 (2) ◽  
pp. E2
Author(s):  
Andrew D. Fine ◽  
Alberto Cardoso ◽  
Albert L. Rhoton
Keyword(s):  
Soft Tissue ◽  
Vertebral Artery ◽  
Posterior Inferior Cerebellar Artery ◽  
Microsurgical Anatomy ◽  
Common Variation ◽  
The Third ◽  
Cerebellar Artery ◽  
The Common ◽  
Bone Anomalies

Object The authors describe the microsurgical anatomy of the posterior inferior cerebellar artery (PICA) with an extradural origin and discuss its importance as a common variation. Methods The microsurgical anatomy of paired PICAs with an extradural origin were examined. Conclusions Five to 20% of PICAs have an extradural origin. In the case described, both PICAs arose extradurally from the third segment of the vertebral artery (VA). Both origins were less than 1 cm proximal to the site at which the VA penetrated the dura and neither PICA gave rise to extradural branches. Extradurally the PICAs coursed parallel to the VA and the C-1 nerve and the three structures penetrated the dura together. Intradurally, the PICAs remained lateral and posterior to the brainstem, whereas, in the common PICA configuration, the first segment of the PICA courses anterior to the medulla. Neither PICA sent branches to the anterior brainstem, which is commonly found in PICAs with an intradural origin. There were no soft-tissue or bone anomalies.

Catalogue reduction techniques

1978 ◽  
Vol 48 ◽  
pp. 389-390 ◽  
Author(s):  
Chr. de Vegt
Keyword(s):  
Adjustment Process ◽  
Proper Motions ◽  
Measuring Process ◽  
Aerial Photogrammetry ◽  
Reduction Techniques ◽  
Observational Technique ◽  
The Common ◽  
Astrometric Data

AbstractReduction techniques as applied to astrometric data material tend to split up traditionally into at least two different classes according to the observational technique used, namely transit circle observations and photographic observations. Although it is not realized fully in practice at present, the application of a blockadjustment technique for all kind of catalogue reductions is suggested. The term blockadjustment shall denote in this context the common adjustment of the principal unknowns which are the positions, proper motions and certain reduction parameters modelling the systematic properties of the observational process. Especially for old epoch catalogue data we frequently meet the situation that no independent detailed information on the telescope properties and other instrumental parameters, describing for example the measuring process, is available from special calibration observations or measurements; therefore the adjustment process should be highly self-calibrating, that means: all necessary information has to be extracted from the catalogue data themselves. Successful applications of this concept have been made already in the field of aerial photogrammetry.

Renilla Bioluminescence: A Morphologic Approach to the Location of Photocytes

1974 ◽  
Vol 32 ◽  
pp. 208-209
Author(s):  
Ben O. Spurlock ◽  
Milton J. Cormier
Keyword(s):  
Excited State ◽  
Ground State ◽  
Molecular Basis ◽  
Light Emission ◽  
Chemical Basis ◽  
Electronic Excited State ◽  
Colonial Form ◽  
The Common ◽  
Eighteenth And Nineteenth Centuries ◽  
Catalyzed Oxidation

The phenomenon of bioluminescence has fascinated layman and scientist alike for many centuries. During the eighteenth and nineteenth centuries a number of observations were reported on the physiology of bioluminescence in Renilla, the common sea pansy. More recently biochemists have directed their attention to the molecular basis of luminosity in this colonial form. These studies have centered primarily on defining the chemical basis for bioluminescence and its control. It is now established that bioluminescence in Renilla arises due to the luciferase-catalyzed oxidation of luciferin. This results in the creation of a product (oxyluciferin) in an electronic excited state. The transition of oxyluciferin from its excited state to the ground state leads to light emission.

Mammalian Bone Marrow Acetylcholinesterase

1982 ◽  
Vol 40 ◽  
pp. 44-45
Author(s):  
Ezzatollah Keyhani
Keyword(s):  
Central Nervous System ◽  
Bone Marrow ◽  
Nervous System ◽  
Common Property ◽  
Extracellular Medium ◽  
The Central Nervous System ◽  
The Common ◽  
Mammalian Bone

Acetylcholinesterase (EC 3.1.1.7) (ACHE) has been localized at cholinergic junctions both in the central nervous system and at the periphery and it functions in neurotransmission. ACHE was also found in other tissues without involvement in neurotransmission, but exhibiting the common property of transporting water and ions. This communication describes intracellular ACHE in mammalian bone marrow and its secretion into the extracellular medium.

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