The art and design of genetic screens: mammalian culture cells

2004 ◽  
Vol 5 (3) ◽  
pp. 179-189 ◽  
Author(s):  
Stefan Grimm
Keyword(s):  
Genetic Screens ◽  
Art And Design ◽  
Culture Cells

The art and design of genetic screens: Caenorhabditis elegans

2002 ◽  
Vol 3 (5) ◽  
pp. 356-369 ◽  
Author(s):  
Erik M. Jorgensen ◽  
Susan E. Mango
Keyword(s):  
Caenorhabditis Elegans ◽  
Genetic Screens ◽  
Art And Design

The art and design of genetic screens: mouse

2005 ◽  
Vol 6 (7) ◽  
pp. 557-567 ◽  
Author(s):  
Benjamin T. Kile ◽  
Douglas J. Hilton
Keyword(s):  
Genetic Screens ◽  
Art And Design

The art and design of genetic screens: maize

2008 ◽  
Vol 9 (3) ◽  
pp. 192-203 ◽  
Author(s):  
Héctor Candela ◽  
Sarah Hake
Keyword(s):  
Genetic Screens ◽  
Art And Design

The art and design of genetic screens: Escherichia coli

2003 ◽  
Vol 4 (6) ◽  
pp. 419-431 ◽  
Author(s):  
Howard A. Shuman ◽  
Thomas J. Silhavy
Keyword(s):  
Escherichia Coli ◽  
Genetic Screens ◽  
Art And Design

The art and design of genetic screens: zebrafish

2001 ◽  
Vol 2 (12) ◽  
pp. 956-966 ◽  
Author(s):  
E. Elizabeth Patton ◽  
Leonard I. Zon
Keyword(s):  
Genetic Screens ◽  
Art And Design

The art and design of genetic screens: RNA interference

2008 ◽  
Vol 9 (7) ◽  
pp. 554-566 ◽  
Author(s):  
Michael Boutros ◽  
Julie Ahringer
Keyword(s):  
Rna Interference ◽  
Genetic Screens ◽  
Art And Design

scholarly journals A High-Throughput, Homogeneous Microplate Assay for Agents That Kill Mammalian Tissue Culture Cells

2003 ◽  
Vol 8 (3) ◽  
pp. 283-291 ◽  
Author(s):  
Michael Pierce ◽  
Chunwei Wang ◽  
Matt Rebentisch ◽  
Mark Endo ◽  
Mark Stump ◽  
...  
Keyword(s):  
Tissue Culture ◽  
Cell Death ◽  
Microplate Assay ◽  
Genetic Screens ◽  
Expression Library ◽  
Protein Fragments ◽  
Chemical Libraries ◽  
Culture Cells ◽  
Tissue Culture Cells ◽  
Homogeneous Assay

Screens for cytostasis/cytoxicity have considerable value for the discovery of therapeutic agents and the investigation of the biology of apoptosis. For instance, genetic screens for proteins, protein fragments, peptides, RNAs, or chemicals that kill tissue culture cells may aid in identifying new cancer therapeutic targets. A microplate assay for cell death is needed to achieve throughputs sufficient to sift through thousands of agents from expression or chemical libraries. The authors describe a homogeneous assay for cell death in tissue culture cells compatible with 96- or 384-well plates. In combination with a previously described system for retroviral packaging and transduction, nearly 6000 expression library clones could be screened per week in a 96-well plate format. The screening system may also prove useful for chemical screens. ( Journal of Biomolecular Screening 2003:283-291)

The art and design of genetic screens: filamentous fungi

2002 ◽  
Vol 3 (9) ◽  
pp. 683-697 ◽  
Author(s):  
Lorna Casselton ◽  
Miriam Zolan
Keyword(s):  
Filamentous Fungi ◽  
Genetic Screens ◽  
Art And Design

The art and design of genetic screens: yeast

2001 ◽  
Vol 2 (9) ◽  
pp. 659-668 ◽  
Author(s):  
Susan L. Forsburg
Keyword(s):  
Genetic Screens ◽  
Art And Design
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