scholarly journals Anatomy and function of an excitatory network in the visual cortex

Nature ◽  
2016 ◽  
Vol 532 (7599) ◽  
pp. 370-374 ◽  
Author(s):  
Wei-Chung Allen Lee ◽  
Vincent Bonin ◽  
Michael Reed ◽  
Brett J. Graham ◽  
Greg Hood ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Excitatory Network ◽  
And Function

Correlation of Cell Shape and Function in the Visual Cortex of the Cat

Nature ◽  
1973 ◽  
Vol 241 (5389) ◽  
pp. 403-405 ◽  
Author(s):  
D. VAN ESSEN ◽  
J. KELLY
Keyword(s):  
Visual Cortex ◽  
Cell Shape ◽  
And Function

scholarly journals Origin and Function of Tuning Diversity in Macaque Visual Cortex

Neuron ◽  
2015 ◽  
Vol 88 (4) ◽  
pp. 819-831 ◽  
Author(s):  
Robbe L.T. Goris ◽  
Eero P. Simoncelli ◽  
J. Anthony Movshon
Keyword(s):  
Visual Cortex ◽  
And Function

scholarly journals Eye opening differentially modulates inhibitory synaptic transmission in the developing visual cortex

2017 ◽  
Author(s):  
Wuqiang Guan ◽  
Jun-Wei Cao ◽  
Lin-Yun Liu ◽  
Zhi-Hao Zhao ◽  
Yinghui Fu ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Synaptic Transmission ◽  
Animal Development ◽  
Quantal Size ◽  
Excitatory Neurons ◽  
Artificial Opening ◽  
Eye Opening ◽  
Fast Spiking ◽  
And Function ◽  
Mouse Visual Cortex

AbstractEye opening, a natural and timed event during animal development, influences cortical circuit assembly and maturation; yet, little is known about its precise effect on inhibitory synaptic connections. Here we show that coinciding with eye opening, the strength of unitary inhibitory postsynaptic currents (uIPSCs) from somatostatin-expressing interneurons (SST-INs) to nearby excitatory neurons, but not interneurons, sharply decreases in layer 2/3 of the mouse visual cortex. In contrast, the strength of uIPSCs from fast-spiking interneurons (FS-INs) to excitatory neurons significantly increases during eye opening. More importantly, these developmental changes can be prevented by dark rearing or binocular lid suture, and reproduced by artificial opening of sutured lids. Mechanistically, this differential maturation of synaptic transmission is accompanied by a significant change in the postsynaptic quantal size. Together, our study reveals a differential regulation in GABAergic circuits in the cortex driven by eye opening likely crucial for cortical maturation and function.

scholarly journals Projections of the Mouse Primary Visual Cortex

2021 ◽  
Vol 15 ◽  
Author(s):  
Arbora Resulaj
Keyword(s):  
Visual Cortex ◽  
Primary Visual Cortex ◽  
Visual Processing ◽  
Brain Area ◽  
Critical Role ◽  
Future Research ◽  
Projection Neurons ◽  
Challenges And Opportunities ◽  
And Function ◽  
To Receive

Lesion or damage to the primary visual cortex (V1) results in a profound loss of visual perception in humans. Similarly, in mice, optogenetic silencing of V1 profoundly impairs discrimination of orientated gratings. V1 is thought to have such a critical role in perception in part due to its position in the visual processing hierarchy. It is the first brain area in the neocortex to receive visual input, and it distributes this information to more than 18 brain areas. Here I review recent advances in our understanding of the organization and function of the V1 projections in the mouse. This progress is in part due to new anatomical and viral techniques that allow for efficient labeling of projection neurons. In the final part of the review, I conclude by highlighting challenges and opportunities for future research.

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