scholarly journals Meconium aspiration syndrome remains a significant problem in the NICU: outcomes and treatment patterns in term neonates admitted for intensive care during a ten-year period

2009 ◽  
Vol 29 (7) ◽  
pp. 497-503 ◽  
Author(s):  
B S Singh ◽  
R H Clark ◽  
R J Powers ◽  
A R Spitzer
Keyword(s):  
Intensive Care ◽  
Meconium Aspiration Syndrome ◽  
Treatment Patterns ◽  
Significant Problem ◽  
Term Neonates ◽  
Meconium Aspiration

Meconium aspiration syndrome in term neonates with normal acid-base status at delivery: Is it different?

2001 ◽  
Vol 184 (7) ◽  
pp. 1422-1426 ◽  
Author(s):  
Sean C. Blackwell ◽  
Julie Moldenhauer ◽  
Sonia S. Hassan ◽  
Mark E. Redman ◽  
Jerrie S. Refuerzo ◽  
...  
Keyword(s):  
Meconium Aspiration Syndrome ◽  
Acid Base ◽  
Term Neonates ◽  
Meconium Aspiration ◽  
Acid Base Status ◽  
Normal Acid

Early Intubation and MAS

PEDIATRICS ◽  
1991 ◽  
Vol 87 (2) ◽  
pp. 269-269
Author(s):  
THOMAS E. WISWELL
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Upper Airway ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration ◽  
The Past ◽  
Early Intubation

In Reply.— I appreciate the comments of Dr Traverse. His opinions and practices closely reflect my own. I, too, am unaware of proven long-term sequelae which can be attributed directly to intubating meconium-stained infants once or twice.1 Additionally, I attempt to remove meconium from the upper airway in all meconium-stained infants, be they vigorous or healthy, or the meconium thick or thin. During the past 5 years, fully one third of infants with the meconium aspiration syndrome (MAS) admitted to our Neonatal Intensive Care Unit had not been intubated and had their tracheae suctioned.

scholarly journals Factors Leading To Meconium Aspiration Syndrome in Term- and Post-term Neonates

Cureus ◽  
2019 ◽  
Author(s):  
Saroop Chand ◽  
Aamna Salman ◽  
Razia Mustafa Abbassi ◽  
Abdul Rehman Siyal ◽  
Fayaz M Ahmad ◽  
...  
Keyword(s):  
Meconium Aspiration Syndrome ◽  
Term Neonates ◽  
Meconium Aspiration

scholarly journals Influence of foetal inflammation on the development of meconium aspiration syndrome in term neonates with meconium-stained amniotic fluid

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7049 ◽  
Author(s):  
Kyoko Yokoi ◽  
Osuke Iwata ◽  
Satoru Kobayashi ◽  
Kanji Muramatsu ◽  
Haruo Goto
Keyword(s):  
Amniotic Fluid ◽  
Apgar Score ◽  
Neonatal Intensive Care ◽  
Meconium Aspiration Syndrome ◽  
Univariate Logistic Regression Analysis ◽  
Term Neonates ◽  
Meconium Aspiration ◽  
Independent Variable ◽  
Male Sex ◽  
Meconium Stained Amniotic Fluid

Background Meconium-stained amniotic fluid is observed in approximately 10–15% of all deliveries; however, only 5% of neonates with meconium-stained amniotic fluid develop meconium aspiration syndrome (MAS). Although foetal distress and subsequent sympathetic stimulation have been considered as the primary upstream events of MAS, this clinical complication sometimes occurs due to other pathologies, such as intraamniotic inflammation. The aim of this study was to investigate whether the incidence of MAS is associated with the presence of funisitis and chorioamnionitis in term neonates with meconium-stained amniotic fluid. Methods Between April 2013 and March 2015, a total of 95 term neonates with meconium-stained amniotic fluid, who were hospitalized at a neonatal intensive care unit, were enrolled in the study. The placenta and umbilical cord were histopathologically examined. Clinical variables and histopathological findings associated with the incidence of MAS were studied. Results A total of 36 neonates developed MAS. Univariate logistic regression analysis revealed that a heavier birth weight, male sex, 1-min Apgar score ≤ 7, funisitis (but not chorioamnionitis), and elevated acute-phase inflammatory reaction score were associated with increased incidence of MAS (all p < 0.05). The multivariate model comprised funisitis (OR = 5.03, 95% CI [1.63–15.5], 1-min Apgar score ≤ 7 (OR = 2.74, 95% CI [1.06–7.09], and male sex (OR = 3.4, 95% CI [1.24–9.34]. Conclusion In neonates with meconium-stained amniotic fluid, funisitis, as well as low 1-min Apgar score and male sex, was identified as an independent variable for MAS development. Intraamniotic inflammation might be involved in the pathological mechanisms of MAS.

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