scholarly journals The incidence and clinical features of meconium aspiration syndrome: a two-year neonatal intensive care experience

2018 ◽  
Author(s):  
Atiye Fedakar
Keyword(s):  
Intensive Care ◽  
Clinical Features ◽  
Neonatal Intensive Care ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration ◽  
Care Experience

Early Intubation and MAS

PEDIATRICS ◽  
1991 ◽  
Vol 87 (2) ◽  
pp. 269-269
Author(s):  
THOMAS E. WISWELL
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Upper Airway ◽  
Meconium Aspiration Syndrome ◽  
Meconium Aspiration ◽  
The Past ◽  
Early Intubation

In Reply.— I appreciate the comments of Dr Traverse. His opinions and practices closely reflect my own. I, too, am unaware of proven long-term sequelae which can be attributed directly to intubating meconium-stained infants once or twice.1 Additionally, I attempt to remove meconium from the upper airway in all meconium-stained infants, be they vigorous or healthy, or the meconium thick or thin. During the past 5 years, fully one third of infants with the meconium aspiration syndrome (MAS) admitted to our Neonatal Intensive Care Unit had not been intubated and had their tracheae suctioned.

scholarly journals Machine Learning Approaches to Predict In-Hospital Mortality among Neonates with Clinically Suspected Sepsis in the Neonatal Intensive Care Unit

2021 ◽  
Vol 11 (8) ◽  
pp. 695
Author(s):  
Jen-Fu Hsu ◽  
Ying-Feng Chang ◽  
Hui-Jun Cheng ◽  
Chi Yang ◽  
Chun-Yuan Lin ◽  
...  
Keyword(s):  
Machine Learning ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Hospital Mortality ◽  
Neonatal Intensive Care Unit ◽  
Clinical Features ◽  
Neonatal Intensive Care ◽  
Learning Approaches ◽  
Suspected Sepsis ◽  
Test Sets

Background: preterm and critically ill neonates often experience clinically suspected sepsis during their prolonged hospitalization in the neonatal intensive care unit (NICU), which can be the initial sign of final adverse outcomes. Therefore, we aimed to utilize machine learning approaches to predict neonatal in-hospital mortality through data-driven learning. Methods: a total of 1095 neonates who experienced clinically suspected sepsis in a tertiary-level NICU in Taiwan between August 2017 and July 2020 were enrolled. Clinically suspected sepsis was defined based on clinical features and laboratory criteria and the administration of empiric antibiotics by clinicians. The variables used for analysis included patient demographics, clinical features, laboratory data, and medications. The machine learning methods used included deep neural network (DNN), k-nearest neighbors, support vector machine, random forest, and extreme gradient boost. The performance of these models was evaluated using the area under the receiver operating characteristic curve (AUC). Results: the final in-hospital mortality of this cohort was 8.2% (90 neonates died). A total of 765 (69.8%) and 330 (30.2%) patients were randomly assigned to the training and test sets, respectively. Regarding the efficacy of the single model that most accurately predicted the outcome, DNN exhibited the greatest AUC (0.923, 95% confidence interval [CI] 0.953–0.893) and the best accuracy (95.64%, 95% CI 96.76–94.52%), Cohen’s kappa coefficient value (0.74, 95% CI 0.79–0.69) and Matthews correlation coefficient value (0.75, 95% CI 0.80–0.70). The top three most influential variables in the DNN importance matrix plot were the requirement of ventilator support at the onset of suspected sepsis, the feeding conditions, and intravascular volume expansion. The model performance was indistinguishable between the training and test sets. Conclusions: the DNN model was successfully established to predict in-hospital mortality in neonates with clinically suspected sepsis, and the machine learning algorithm is applicable for clinicians to gain insights and have better communication with families in advance.

Effect of Community Size on Eligibility for Early Intervention for Infants With a Neonatal Intensive Care Experience

2013 ◽  
Vol 30 (3) ◽  
pp. 259-264 ◽  
Author(s):  
Holly Roberts ◽  
Howard Needelman ◽  
Barbara Jackson ◽  
Carol McMorris ◽  
Abbey Munyon
Keyword(s):  
Intensive Care ◽  
Early Intervention ◽  
Neonatal Intensive Care ◽  
Community Size ◽  
Care Experience

scholarly journals Clinical Features and Outcomes of Patients in Neonatal Intensive Care Requiring Laryngologic Consultation for Airway Disorders

2017 ◽  
Vol 60 (1) ◽  
pp. 24-29
Author(s):  
Jin Youp Kim ◽  
Doh Young Lee ◽  
Hyun Chang ◽  
Dong Wook Kim ◽  
Myung-Whun Sung ◽  
...  
Keyword(s):  
Intensive Care ◽  
Clinical Features ◽  
Neonatal Intensive Care

scholarly journals Sildenafil Exposure in the Neonatal Intensive Care Unit

2018 ◽  
Vol 36 (03) ◽  
pp. 262-267 ◽  
Author(s):  
Elizabeth Thompson ◽  
Krystle Perez ◽  
P. Smith ◽  
Reese Clark ◽  
Matthew Laughon ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Retrospective Cohort ◽  
Neonatal Intensive Care ◽  
Neonatal Intensive Care Units ◽  
Meconium Aspiration ◽  
Safety And Efficacy ◽  
Respiratory Outcome ◽  
Pulmonary Arterial ◽  
Substantial Morbidity

Objective Pulmonary hypertension causes substantial morbidity and mortality in infants. Although Food and Drug Administration approved to treat pulmonary arterial hypertension in adults, sildenafil is not approved for infants. We sought to describe sildenafil exposure and associated diagnoses and outcomes in infants. Study Design Retrospective cohort of neonates discharged from more than 300 neonatal intensive care units from 2001 to 2016. Results Sildenafil was administered to 1,336/1,161,808 infants (0.11%; 1.1 per 1,000 infants); 0/35,977 received sildenafil in 2001 versus 151/90,544 (0.17%; 1.7 per 1,000 infants) in 2016. Among infants <32 weeks' gestational age (GA) with enough data to determine respiratory outcome, 666/704 (95%) had bronchopulmonary dysplasia (BPD). Among infants ≥32 weeks GA, 248/455 (55%) had BPD and 76/552 (14%) were diagnosed with meconium aspiration. Overall, 209/921 (23%) died prior to discharge. Conclusion The use of sildenafil has increased since 2001. Exposed infants were commonly diagnosed with BPD. Further studies evaluating dosing, safety, and efficacy of sildenafil are needed.

The Neonatal Intensive Care Experience

1991 ◽  
Vol 20 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Jeanne Donelan Rapack
Keyword(s):  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Care Experience
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