scholarly journals 99Tcm-octreotide scintigraphy and serum eye muscle antibodies in evaluation of active thyroid-associated ophthalmopathy

Eye ◽  
2017 ◽  
Vol 31 (5) ◽  
pp. 668-676 ◽  
Author(s):  
B Sun ◽  
Z Zhang ◽  
C Dong ◽  
Y Zhang ◽  
C Yan ◽  
...  
Keyword(s):  
Eye Muscle ◽  
Thyroid Associated Ophthalmopathy ◽  
Octreotide Scintigraphy

ROLE OF EYE MUSCLE ANTIBODY MEASUREMENT IN DIAGNOSIS OF THYROID-ASSOCIATED OPHTHALMOPATHY: A LABORATORY UPDATE

1998 ◽  
Vol 4 (3) ◽  
pp. 127-132 ◽  
Author(s):  
Sumihisa Kubota, MD ◽  
Kazuaki Gunji, MD ◽  
Carol Stolarski, BS ◽  
John S. Kennerdell, MD ◽  
Jack R. Wall, MD, PhD
Keyword(s):  
Eye Muscle ◽  
Thyroid Associated Ophthalmopathy

Antibodies to orbital tissues in thyroid-associated ophthalmopathy

1992 ◽  
Vol 126 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Petros Perros ◽  
Pat Kendall-Taylor
Keyword(s):  
Autoimmune Diseases ◽  
Extraocular Muscle ◽  
Enzyme Linked Immunosorbent Assay ◽  
Eye Muscle ◽  
Autoimmune Attack ◽  
Thyroid Associated Ophthalmopathy ◽  
Binding Antibody ◽  
Antibody Levels ◽  
Orbital Fibroblasts ◽  
Normal Controls

Thyroid-associated ophthalmopathy is thought to be an autoimmune disease affecting the orbit. The precise pathogenetic mechanisms are not known, but extraocular muscle and/or orbital fibroblasts are the likely targets of the autoimmune attack. Sera from 41 normal controls, 79 patients with thyroid-associated ophthalmopathy and 72 patients with other autoimmune diseases were examined for antibodies to cultured orbital fibroblasts and extraocular muscle by enzyme-linked immunosorbent assay. Orbital fibroblast antibody levels varied widely in all subject groups studied, and failed to distinguish patients with thyroid-associated ophthalmopathy from patients with other autoimmune diseases or controls. Eye-muscle binding antibody levels were higher amongst patients with ophthalmopathy compared to normal controls and patients with Graves' hyperthyroidism without clinical evidence of ophthalmopathy. Furthermore, eye-muscle binding antibody levels were found to be particularly high in patients with ophthalmopathy and concurrent dermopathy, and in patients with ophthalmic (euthyroid) Graves' disease.

Eye Muscle Antibodies and Subtype of Thyroid-Associated Ophthalmopathy

Thyroid ◽  
2002 ◽  
Vol 12 (3) ◽  
pp. 187-191 ◽  
Author(s):  
Matthias Kaspar ◽  
Curtis Archibald ◽  
Anna Maria De Bellis ◽  
Audrey Wu Li ◽  
Masayo Yamada ◽  
...  
Keyword(s):  
Eye Muscle ◽  
Thyroid Associated Ophthalmopathy
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