scholarly journals Heavy tamponade 2 Densiron 68® in routine clinical practice: anatomical and functional outcomes of a consecutive case series

Eye ◽  
2008 ◽  
Vol 22 (10) ◽  
pp. 1360-1365 ◽  
Author(s):  
T Stappler ◽  
H Heimann ◽  
D Wong ◽  
S K Gibran ◽  
C Groenewald ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Functional Outcomes ◽  
Case Series ◽  
Routine Clinical Practice ◽  
Consecutive Case

scholarly journals Implementing Narrative Exposure Therapy for unaccompanied asylum-seeking minors with post-traumatic stress disorder: A pilot feasibility report

2019 ◽  
Vol 25 (1) ◽  
pp. 213-226 ◽  
Author(s):  
Glorianne Said ◽  
Dorothy King
Keyword(s):  
Clinical Practice ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Functional Outcomes ◽  
Stress Disorder ◽  
Exposure Therapy ◽  
Routine Clinical Practice ◽  
Post Traumatic Stress ◽  
Narrative Exposure Therapy ◽  
Post Traumatic

There are high rates of post-traumatic stress disorder (PTSD) in unaccompanied asylum-seeking minors (UAM) and there is a requirement for feasible, acceptable and evidence-based treatments. Narrative Exposure Therapy (NET) is a short-term treatment for PTSD following multiple traumatic events. This article aims to examine the applicability of NET for UAM in routine clinical practice and to provide preliminary feasibility, acceptability and effectiveness data. The participants were four UAM receiving NET within a dedicated child and adolescent mental health service for refugee children. Semi-structured interviews were conducted to understand the acceptability of this approach and standardised measures of PTSD were used to provide preliminary data regarding the effectiveness of NET for these clients. The clients attended NET consistently with few missed appointments. At post-treatment, two clients’ symptom scores were below the clinical cut-off for PTSD and all three clients who completed NET met reliable improvement criteria. The clients reported improvements in functional outcomes and mentioned that they would encourage other young people with similar difficulties to engage in NET. This study was limited by the small sample size and naturalistic time limitations in clinicians’ contracts. This article highlights that it is possible to implement NET within routine clinical practice and observed improvements in PTSD symptoms and functional outcomes for UAM.

scholarly journals Clinical Characteristics and Outcome in Patients with Sphenoid Allergic Fungal Disease

2015 ◽  
Vol 22 (1) ◽  
pp. 17-23
Author(s):  
Hisham B. Alem
Keyword(s):  
Clinical Practice ◽  
Clinical Characteristics ◽  
Case Series ◽  
Fungal Disease ◽  
Routine Clinical Practice ◽  
Diagnosis And Treatment ◽  
Atypical Presentation ◽  
Uncommon Disease ◽  
Diagnostic Condition

Sphenoid Allergic Fungal Disease is an uncommon disease, usually non-aggressive course, as reported in the literature. It is usually undiagnosed because of its atypical presentation. This series reports four cases of Sphenoid Allergic Fungal Disease presenting with distinct symptoms. This article describes the clinician's experience in the diagnosis and treatment of Sphenoid Allergic Fungal Disease. This article also stresses the importance of competency and expertise of the clinician to be more suspicious of the Sphenoid Allergic Fungal Disease in their routine clinical practice as it is not a usual diagnostic condition. This four-case series will also explain the importance of various investigative procedures and radiological fi ndings to be incorporated as required for diagnosing and treating the cases of Sphenoid Allergic Fungal Disease.  

scholarly journals Insights for the application of TILs and AR in the treatment of TNBC in routine clinical practice

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Agnese Losurdo ◽  
Rita De Sanctis ◽  
Bethania Fernandes ◽  
Rosalba Torrisi ◽  
Giovanna Masci ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Older Patients ◽  
Case Series ◽  
Tumor Infiltrating Lymphocytes ◽  
Distant Metastases ◽  
Routine Clinical Practice ◽  
Ki 67 ◽  
Younger Women ◽  
Clinical Variables ◽  
New Biomarkers

AbstractTriple negative breast cancer (TNBC), usually presenting with a very aggressive phenotype, is a heterogeneous entity. We aim to discuss new biomarkers, suitable for prognostic and predictive purposes. We retrospectively collected clinical variables and immunohistochemical characteristics of early TNBCs, specifically focusing on the prognostic and predictive significance of tumor infiltrating lymphocytes (TILs) and androgen receptor (AR) expression, assessing their correlation with clinical variables. Among 159 patients, TILs were significantly higher in younger patients and with lower BMI, and in tumors with higher ki-67 and greater nodal involvement; conversely, AR was significantly higher in older patients and in tumors with lower ki-67. Interestingly and in line with literature, both TILs level and ARs expression were lower within metastatic sites, in patients who developed distant metastases, compared to those found in the primary site. Small (pT1) and node negative tumors were highly represented and no correlation of either TILs or AR with prognosis could be observed. Our findings support the use of stromal TILs to identify a more aggressive, but chemo-sensitive phenotype, mostly represented in younger women, while AR may identify a less aggressive, slow-growing luminal TNBC subtype, more common among older patients. TILs and AR are worth implementing in routine clinical practice to refine prognosis even if, in our case series, we couldn’t identify a significant correlation of the two variables with either disease-free and overall survival.

Use of Nicergoline as Adjunctive Treatment of Neurotrophic Keratitis in Routine Clinical Practice: A Case Series

2021 ◽  
pp. 1-5
Author(s):  
L. Miguel-Escuder ◽  
C. Rocha-de-Lossada ◽  
N. Sabater-Cruz ◽  
José-María Sánchez-González ◽  
F. Spencer ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Case Series ◽  
Routine Clinical Practice ◽  
Adjunctive Treatment ◽  
Neurotrophic Keratitis

Diagnosis and Management of Cardiomyopathies – A Focus on Genetics, Cardiac Magnetic Resonance and Clinical Features

2011 ◽  
Vol 7 (3) ◽  
pp. 225
Author(s):  
Gianfranco Sinagra ◽  
Michele Moretti ◽  
Giancarlo Vitrella ◽  
Marco Merlo ◽  
Rossana Bussani ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Imaging Techniques ◽  
Molecular Genetic ◽  
Molecular Genetic Analysis ◽  
Routine Clinical Practice ◽  
Clinical Approach ◽  
Diagnosis And Management ◽  
Made In

In recent years, outstanding progress has been made in the diagnosis and treatment of cardiomyopathies. Genetics is emerging as a primary point in the diagnosis and management of these diseases. However, molecular genetic analyses are not yet included in routine clinical practice, mainly because of their elevated costs and execution time. A patient-based and patient-oriented clinical approach, coupled with new imaging techniques such as cardiac magnetic resonance, can be of great help in selecting patients for molecular genetic analysis and is crucial for a better characterisation of these diseases. This article will specifically address clinical, magnetic resonance and genetic aspects of the diagnosis and management of cardiomyopathies.

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