A case series of CBT‐T in routine clinical practice

Author(s):  
Charlotte Rose ◽  
Ioanna Bakopoulou ◽  
Tamas Novak
2015 ◽  
Vol 22 (1) ◽  
pp. 17-23
Author(s):  
Hisham B. Alem

Sphenoid Allergic Fungal Disease is an uncommon disease, usually non-aggressive course, as reported in the literature. It is usually undiagnosed because of its atypical presentation. This series reports four cases of Sphenoid Allergic Fungal Disease presenting with distinct symptoms. This article describes the clinician's experience in the diagnosis and treatment of Sphenoid Allergic Fungal Disease. This article also stresses the importance of competency and expertise of the clinician to be more suspicious of the Sphenoid Allergic Fungal Disease in their routine clinical practice as it is not a usual diagnostic condition. This four-case series will also explain the importance of various investigative procedures and radiological fi ndings to be incorporated as required for diagnosing and treating the cases of Sphenoid Allergic Fungal Disease.  


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Agnese Losurdo ◽  
Rita De Sanctis ◽  
Bethania Fernandes ◽  
Rosalba Torrisi ◽  
Giovanna Masci ◽  
...  

AbstractTriple negative breast cancer (TNBC), usually presenting with a very aggressive phenotype, is a heterogeneous entity. We aim to discuss new biomarkers, suitable for prognostic and predictive purposes. We retrospectively collected clinical variables and immunohistochemical characteristics of early TNBCs, specifically focusing on the prognostic and predictive significance of tumor infiltrating lymphocytes (TILs) and androgen receptor (AR) expression, assessing their correlation with clinical variables. Among 159 patients, TILs were significantly higher in younger patients and with lower BMI, and in tumors with higher ki-67 and greater nodal involvement; conversely, AR was significantly higher in older patients and in tumors with lower ki-67. Interestingly and in line with literature, both TILs level and ARs expression were lower within metastatic sites, in patients who developed distant metastases, compared to those found in the primary site. Small (pT1) and node negative tumors were highly represented and no correlation of either TILs or AR with prognosis could be observed. Our findings support the use of stromal TILs to identify a more aggressive, but chemo-sensitive phenotype, mostly represented in younger women, while AR may identify a less aggressive, slow-growing luminal TNBC subtype, more common among older patients. TILs and AR are worth implementing in routine clinical practice to refine prognosis even if, in our case series, we couldn’t identify a significant correlation of the two variables with either disease-free and overall survival.


Eye ◽  
2008 ◽  
Vol 22 (10) ◽  
pp. 1360-1365 ◽  
Author(s):  
T Stappler ◽  
H Heimann ◽  
D Wong ◽  
S K Gibran ◽  
C Groenewald ◽  
...  

Author(s):  
L. Miguel-Escuder ◽  
C. Rocha-de-Lossada ◽  
N. Sabater-Cruz ◽  
José-María Sánchez-González ◽  
F. Spencer ◽  
...  

2011 ◽  
Vol 7 (3) ◽  
pp. 225
Author(s):  
Gianfranco Sinagra ◽  
Michele Moretti ◽  
Giancarlo Vitrella ◽  
Marco Merlo ◽  
Rossana Bussani ◽  
...  

In recent years, outstanding progress has been made in the diagnosis and treatment of cardiomyopathies. Genetics is emerging as a primary point in the diagnosis and management of these diseases. However, molecular genetic analyses are not yet included in routine clinical practice, mainly because of their elevated costs and execution time. A patient-based and patient-oriented clinical approach, coupled with new imaging techniques such as cardiac magnetic resonance, can be of great help in selecting patients for molecular genetic analysis and is crucial for a better characterisation of these diseases. This article will specifically address clinical, magnetic resonance and genetic aspects of the diagnosis and management of cardiomyopathies.


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