scholarly journals Dietary chemoprevention of clastogenic effects of 3,4-benzo(a)pyrene by Emblica officinalis Gaertn. fruit extract

1997 ◽  
Vol 76 (10) ◽  
pp. 1279-1283 ◽  
Author(s):  
P Nandi ◽  
G Talukder ◽  
A Sharma
Keyword(s):  
Emblica Officinalis ◽  
Fruit Extract ◽  
Dietary Chemoprevention

Augmented Reversal of Cisplatin-Induced Delayed Gastric Emptying by Amla (Emblica Officinalis) Fruit Extract in Sprague-Dawley Rats

2017 ◽  
Vol 15 (5) ◽  
pp. 684-691
Author(s):  
Asad Ahmad ◽  
Mohammad Khushtar ◽  
Ranjan Kumar ◽  
Badruddeen ◽  
Ambreena Riyaz ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Delayed Gastric Emptying ◽  
Emblica Officinalis ◽  
Sprague Dawley ◽  
Fruit Extract ◽  
Sprague Dawley Rats

scholarly journals Ethanolic Fruit Extract of Emblica officinalis Suppresses Neuroinflammation in Microglia and Promotes Neurite Outgrowth in Neuro2a Cells

2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Sataporn Phochantachinda ◽  
Duangthip Chatchaisak ◽  
Piya Temviriyanukul ◽  
Anchana Chansawang ◽  
Pornsiri Pitchakarn ◽  
...  
Keyword(s):  
Neurite Outgrowth ◽  
Ethanolic Extract ◽  
Neuroprotective Activity ◽  
Emblica Officinalis ◽  
Fruit Extract ◽  
Promising Strategy ◽  
Bv2 Cells ◽  
Neuro2a Cells ◽  
Factor Α

Inhibiting neuroinflammation and modulating neurite outgrowth could be a promising strategy to prevent neurological disorders. Emblica officinalis (EO) may be a potent agent against them. Although EO extract reportedly has anti-inflammatory properties in macrophages, there is limited knowledge about its neuroprotective activity by suppressing microglia-mediated proinflammatory cytokine production and inducing neurite outgrowth. The present study aimed to elucidate the effect of EO fruit extract on the lipopolysaccharide- (LPS-) induced neuroinflammation using microglial (BV2) and neuroblastoma (Neuro2a) cells. The results demonstrated that, in LPS-treated BV2 cells, EO fruit extract reduced nitric oxide, interleukin-6, and tumor necrotic factor-α production. It also enhanced the neurite length of Neuro2a cells, which was linked to the upregulation of TuJ1 and MAP2 expressions. In conclusion, these findings indicate that the ethanolic extract of EO fruits has promising neuroprotective potential to exhibit antineuroinflammation activity and accelerative effect on neurite outgrowth in vitro. Therefore, EO fruit extract can be considered a novel herbal medicine candidate for managing neuroinflammatory diseases.

Antitussive activity of the fruit extract of Emblica officinalis Gaertn. (Euphorbiaceae)

Phytomedicine ◽  
2003 ◽  
Vol 10 (6-7) ◽  
pp. 583-589 ◽  
Author(s):  
G. Nosál'ová ◽  
J. Mokrý ◽  
K.M. Tareq Hassan
Keyword(s):  
Emblica Officinalis ◽  
Fruit Extract ◽  
Antitussive Activity
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