scholarly journals SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-κB pathways in RAW 264.7 macrophages

2009 ◽  
Vol 30 (10) ◽  
pp. 1428-1435 ◽  
Author(s):  
Jun-xia Wang ◽  
Li-fei Hou ◽  
Yang Yang ◽  
Wei Tang ◽  
Ying Li ◽  
...  
Keyword(s):  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Raw 264.7 ◽  
Artemisinin Derivative ◽  
Raw 264.7 Macrophages ◽  
Inflammatory Cytokine Production

scholarly journals Inhibitory Effect of N,N-Didesmethylgrossularine-1 on Inflammatory Cytokine Production in Lipopolysaccharide-Stimulated RAW 264.7 Cells

Marine Drugs ◽  
2009 ◽  
Vol 7 (4) ◽  
pp. 589-599 ◽  
Author(s):  
Taiko Oda ◽  
Jong-Soo Lee ◽  
Yuta Sato ◽  
Yasuaki Kabe ◽  
Satoshi Sakamoto ◽  
...  
Keyword(s):  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Inhibitory Effect ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Inflammatory Cytokine Production

scholarly journals Sorghum [Sorghum bicolor(L.) Moench] Genotypes with Contrasting Polyphenol Compositions Differentially Modulate Inflammatory Cytokines in Mouse Macrophages

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Davina H. Rhodes ◽  
Stephen Kresovich
Keyword(s):  
Cytokine Production ◽  
Raw 264.7 ◽  
Raw 264.7 Macrophages ◽  
Inflammatory Cytokine Production ◽  
Mouse Macrophages ◽  
Health Promoting ◽  
Sorghum Genotypes ◽  
Ethanol Extracts ◽  
Sorghum Grain ◽  
Necrosis Factor

This study sought to characterize and compare anti-inflammatory effects of twenty sorghum accessions with contrasting grain polyphenol concentrations but similar genetic backgrounds (based on a genomewide estimate of relatedness). Cell viability, tumor necrosis factor- (TNF-)α, and interleukin- (IL-) 6 were measured in RAW 264.7 macrophages treated with increasing doses (0, 15, 30, and 60 μg/mL) of sorghum ethanol extracts and stimulated with lipopolysaccharide (LPS). Extract dose had a significant effect on TNF-αand IL-6, with a trend of cytokines decreasing between 0 μg/mL and 15 μg/mL of sorghum extract. Genotype also had a significant effect on the cytokines, with extracts from four accessions significantly decreasing TNF-αand/or IL-6. Cells treated with 3-deoxyanthocyanidin-containing accessions had less cytokine production than non-3-deoxyanthocyanidin accessions, whereas cells treated with proanthocyanidin-containing accessions had more cytokine production than cells treated with nonproanthocyanidin accessions. Additionally, there was a significant effect of theTannin1allele on TNF-αand IL-6. Our results demonstrate that sorghum genotypes differentially modulate induction of inflammatory cytokine production in RAW 264.7 macrophages and that specialty grain has the potential to be tailored by controlling traits at the nucleotide level. This study adds to our knowledge of sorghum health effects and contributes to efforts aimed at developing health-promoting sorghum grain.

Dendritic cells sub-sets are associated with inflammatory cytokine production in progressive vitiligo disease

2021 ◽  
Author(s):  
Niharika Srivastava ◽  
Anuradha Bishnoi ◽  
Davinder Parsad ◽  
Muthu Sendhil Kumaran ◽  
Keshavamurthy Vinay ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Inflammatory Cytokine Production
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