Targeted delivery of nitric oxide

Nature ◽  
2001 ◽  
Vol 409 (6820) ◽  
pp. 577-578 ◽  
Author(s):  
Steven S. Gross
Keyword(s):  
Nitric Oxide ◽  
Targeted Delivery

A multifunctional nanoplatform for lysosome targeted delivery of nitric oxide and photothermal therapy under 808 nm near-infrared light

2016 ◽  
Vol 4 (27) ◽  
pp. 4667-4674 ◽  
Author(s):  
Hui-Jing Xiang ◽  
Min Guo ◽  
Lu An ◽  
Shi-Ping Yang ◽  
Qian-Ling Zhang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Targeted Delivery ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Nir Light

NIR light induced spatiotemporal delivery of NO to lysosome accompanied by hyperthermia was realized.

Targeted delivery of nitric oxide via a ‘bump-and-hole’-based enzyme–prodrug pair

2018 ◽  
Vol 15 (2) ◽  
pp. 151-160 ◽  
Author(s):  
Jingli Hou ◽  
Yiwa Pan ◽  
Dashuai Zhu ◽  
Yueyuan Fan ◽  
Guowei Feng ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Targeted Delivery

Tumor cell specific and lysosome-targeted delivery of nitric oxide for enhanced photodynamic therapy triggered by 808 nm near-infrared light

2016 ◽  
Vol 52 (1) ◽  
pp. 148-151 ◽  
Author(s):  
Hui-Jing Xiang ◽  
Qiao Deng ◽  
Lu An ◽  
Min Guo ◽  
Shi-Ping Yang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Photodynamic Therapy ◽  
Tumor Cell ◽  
Cancer Cell ◽  
Targeted Delivery ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light

A novel cancer cell lysosome-targetable multifunctional NO-delivery nanoplatform (Lyso-Ru-NO@FA@C-TiO2) (1) was developed.

Ruthenium nitrosyl functionalized graphene quantum dots as an efficient nanoplatform for NIR-light-controlled and mitochondria-targeted delivery of nitric oxide combined with photothermal therapy

2017 ◽  
Vol 53 (22) ◽  
pp. 3253-3256 ◽  
Author(s):  
Min Guo ◽  
Hui-Jing Xiang ◽  
Yi Wang ◽  
Qian-Ling Zhang ◽  
Lu An ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Quantum Dots ◽  
Targeted Delivery ◽  
Photothermal Therapy ◽  
Graphene Quantum Dots ◽  
Antitumor Efficacy ◽  
Functionalized Graphene ◽  
Ruthenium Nitrosyl ◽  
Nir Light

Targeted delivery of NO accompanied by photothermal therapy shows efficient in vivo antitumor efficacy.

scholarly journals Synthesis of N-Pyridin-2-ylmethyl and N-Quinolin-2-ylmethyl ­Substituted Ethane-1,2-diamines

SynOpen ◽  
2017 ◽  
Vol 01 (01) ◽  
pp. 0147-0155 ◽  
Author(s):  
Yi-Qiu Yang ◽  
Long-Zhi Ke ◽  
Gui-Fei Wang ◽  
Shu-Yong Song ◽  
Ming-Ning Qiu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Metal Ions ◽  
Targeted Delivery ◽  
Metal Ion ◽  
Synthesis And Characterization ◽  
Long Wavelength ◽  
Initial Work ◽  
Wavelength Light

Two N-(2-(bis(pyridin-2-ylmethyl)amino)ethyl)quinoline-2-carboxamides and two N-(2-(bis(quinolin-2-ylmethyl)amino)ethyl)quinoline-2-carboxamides have been synthesized. These structures contain five nitrogen atoms that can form coordinate bonds with metal ions such as Mn(II) and Fe(II). An additional coordinating bond can be formed between the metal ion and a neutral molecule of nitric oxide (NO). The resultant complexes are potentially useful agents for targeted delivery of NO to in vivo biological sites such as tumors, where the NO is released upon irradiation with long-wavelength light. Initial work involving the synthesis and characterization of these analogues is reported here.

scholarly journals Local delivery of nitric oxide: Targeted delivery of therapeutics to bone and connective tissues

2012 ◽  
Vol 64 (12) ◽  
pp. 1177-1188 ◽  
Author(s):  
Scott P. Nichols ◽  
Wesley L. Storm ◽  
Ahyeon Koh ◽  
Mark H. Schoenfisch
Keyword(s):  
Nitric Oxide ◽  
Targeted Delivery ◽  
Local Delivery ◽  
Connective Tissues
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