ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

Nature ◽  
1983 ◽  
Vol 306 (5944) ◽  
pp. 707-709 ◽  
Author(s):  
D. DeFeo-Jones ◽  
E. M. Scolnick ◽  
R. Koller ◽  
R. Dhar
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Related Gene ◽  
Gene Sequences

SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae

1994 ◽  
Vol 14 (8) ◽  
pp. 5223-5228
Author(s):  
C Dollard ◽  
S L Ricupero-Hovasse ◽  
G Natsoulis ◽  
J D Boeke ◽  
F Winston
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Differential Expression ◽  
Double Mutant ◽  
The Other ◽  
Histone Genes ◽  
Related Gene ◽  
Histone Proteins ◽  
Histone Locus

The Saccharomyces cerevisiae genome contains four loci that encode histone proteins. Two of these loci, HTA1-HTB1 and HTA2-HTB2, each encode histones H2A and H2B. The other two loci, HHT1-HHF1 and HHT2-HHF2, each encode histones H3 and H4. Because of their redundancy, deletion of any one histone locus does not cause lethality. Previous experiments demonstrated that mutations at one histone locus, HTA1-HTB1, do cause lethality when in conjunction with mutations in the SPT10 gene. SPT10 has been shown to be required for normal levels of transcription of several genes in S. cerevisiae. Motivated by this double-mutant lethality, we have now investigated the interactions of mutations in SPT10 and in a functionally related gene, SPT21, with mutations at each of the four histone loci. These experiments have demonstrated that both SPT10 and SPT21 are required for transcription at two particular histone loci, HTA2-HTB2 and HHF2-HHT2, but not at the other two histone loci. These results suggest that under some conditions, S. cerevisiae may control the level of histone proteins by differential expression of its histone genes.

scholarly journals PCR amplification of SRY-related gene sequences reveals evolutionary conservation of the SRY-box motif.

1993 ◽  
Vol 2 (3) ◽  
pp. 218-222 ◽  
Author(s):  
A M Coriat ◽  
U Muller ◽  
J L Harry ◽  
D Uwanogho ◽  
P T Sharpe
Keyword(s):  
Pcr Amplification ◽  
Evolutionary Conservation ◽  
Related Gene ◽  
Gene Sequences

Identification of ACT4, a novel essential actin-related gene in the yeast Saccharomyces cerevisiae

Yeast ◽  
1996 ◽  
Vol 12 (9) ◽  
pp. 839-848 ◽  
Author(s):  
Meng-Er Huang ◽  
Jean-Luc Souciet ◽  
Jean-Claude Chuat ◽  
Francis Galibert
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Related Gene ◽  
Yeast Saccharomyces Cerevisiae

scholarly journals DNA CTG triplet repeats involved in dynamic mutations of neurologically related gene sequences form stable duplexes

1995 ◽  
Vol 23 (21) ◽  
pp. 4303-4311 ◽  
Author(s):  
Kenneth G. Smith ◽  
Ji Jie ◽  
George E. Fox ◽  
Xiaolian Gao
Keyword(s):  
Related Gene ◽  
Triplet Repeats ◽  
Gene Sequences ◽  
Dynamic Mutations

scholarly journals Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.

1992 ◽  
Vol 118 (1) ◽  
pp. 109-120 ◽  
Author(s):  
M A Hoyt ◽  
L He ◽  
K K Loo ◽  
W S Saunders
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Cell Viability ◽  
Chromosome Segregation ◽  
Heavy Chain ◽  
Mitotic Spindle ◽  
Spindle Assembly ◽  
Gene Products ◽  
Related Gene ◽  
Mitotic Spindle Assembly ◽  
Spindle Microtubules

Two Saccharomyces cerevisiae genes, CIN8 and KIP1 (a.k.a. CIN9), were identified by their requirement for normal chromosome segregation. Both genes encode polypeptides related to the heavy chain of the microtubule-based force-generating enzyme kinesin. Cin8p was found to be required for pole separation during mitotic spindle assembly at 37 degrees C, although overproduced Kip1p could substitute. At lower temperatures, the activity of at least one of these proteins was required for cell viability, indicating that they perform an essential but redundant function. Cin8p was observed to be a component of the mitotic spindle, colocalizing with the microtubules that lie between the poles. Taken together, these findings suggest that these proteins interact with spindle microtubules to produce an outwardly directed force acting upon the poles.

Small Differences in SUC Gene Sequences Impact Saccharomyces cerevisiae Invertase Activity and Specificity toward Fructans with Different Chain Lengths

2021 ◽  
Vol 69 (6) ◽  
pp. 1925-1935
Author(s):  
Jitka Laurent ◽  
Anouk Aerts ◽  
Jonathan Gordon ◽  
Purvi Gupta ◽  
Arnout R. D. Voet ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Invertase Activity ◽  
Gene Sequences ◽  
Chain Lengths

scholarly journals Charcot-Marie-Tooth-related Gene GDAP1 Complements Cell Cycle Delay at G2/M Phase in Saccharomyces cerevisiae fis1 Gene-defective Cells

2011 ◽  
Vol 286 (42) ◽  
pp. 36777-36786 ◽  
Author(s):  
Anna Estela ◽  
David Pla-Martín ◽  
Maribel Sánchez-Piris ◽  
Hiromi Sesaki ◽  
Francesc Palau
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Cell Cycle ◽  
Related Gene ◽  
Charcot Marie Tooth ◽  
Cell Cycle Delay ◽  
M Phase

An acyl-CoA:cholesterol acyltransferase (ACAT)-related gene is involved in the accumulation of triacylglycerols in Sacchoromyces cerevisiae

2000 ◽  
Vol 28 (6) ◽  
pp. 700-702 ◽  
Author(s):  
L. Sandager ◽  
A. Dahlqvist ◽  
A. Banaś ◽  
U. Ståhl ◽  
M. Lenman ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Cholesterol Acyltransferase ◽  
Diacylglycerol Acyltransferase ◽  
Yeast Genome ◽  
Related Gene ◽  
Animal Tissues ◽  
Sterol Esters ◽  
Genes Encoding ◽  
Major Route ◽  
Sequence Similarities

The major route for the synthesis of triacylglycerol (TAG) in yeast as well as in all TAG-accumulating organisms has been suggested to occur via the acylation of diacylglycerol (DAG) by acyl-CoA: diacylglycerol acyltransferase (DAGAT). Genes encoding DAGAT have been identified in both plant and animal tissues. These genes show strong sequence similarities to genes encoding acyl-CoA: cholesterol acyltransferase (ACAT). So far no Saccharomyces cerevisiae DAGAT gene has been published; however, two ACAT-like genes, ARE1 and ARE2, are present in the yeast genome. Both these genes have been suggested to be involved in the synthesis of sterol esters. We have now shown that the ARE1 gene in yeast also is involved in the synthesis of TAG, whereas the ARE2 gene is more specifically involved in the synthesis of sterol esters.

scholarly journals High Yield Expression of the Human Ether-à-Go-Go Related Gene (HERG) in Saccharomyces Cerevisiae

2014 ◽  
Vol 106 (2) ◽  
pp. 137a
Author(s):  
Karen Molbaek ◽  
Peter Scharff-Poulsen ◽  
Dan A. Klaerke ◽  
Per Amstrup Pedersen
Keyword(s):  
Saccharomyces Cerevisiae ◽  
High Yield ◽  
Related Gene
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