Five Hundred and Fifty Five Depressive Patients: Characteristics of These Patients and Factors Related to Clinical Improvement

1969 ◽  
Author(s):  
J. Richard Wittenborn
Keyword(s):  
Clinical Improvement ◽  
Depressive Patients

Lexical decision tasks in depressive patients: semantic priming before and after clinical improvement

2002 ◽  
Vol 17 (2) ◽  
pp. 69-74 ◽  
Author(s):  
C. Besche-Richard ◽  
C. Passerieux ◽  
M.-C. Hardy-Baylé
Keyword(s):  
Lexical Decision ◽  
Lexical Decision Task ◽  
Clinical Improvement ◽  
Semantic Priming ◽  
Rating Scales ◽  
Psychomotor Retardation ◽  
Clinical Population ◽  
Decision Task ◽  
Control Subjects ◽  
Depressive Patients

SummaryThis study was designed to evaluate the effect of semantic priming with a lexical decision task in 22 depressed patients (DSM-III-R, 1987) and 30 control subjects. These patients were evaluated twice: first when they arrived at the hospital, and secondly, after clinical improvement. Clinical improvement was evaluated using standard depression rating scales. A lexical decision task involving semantic relations (related vs. unrelated, e.g., apple-pear) was used to evaluate the processing of semantic information. The results showed that, for the first evaluation, the depressives presented similar semantic priming to control subjects. When we compared semantic priming in the first and the second passes, we observed that its amplitude was identical. The sole difference between the two passes concerns the global reaction time in the depressive group. This last result suggested that, with clinical improvement, the characteristic psychomotor retardation declines. One of the major results concerns the fact that severe depressive patients (first pass) exhibit normal semantic priming in a lexical decision task. These results indicate, in this clinical population, the preservation of controlled processes implicated in this lexical decision task.

scholarly journals Changes in the levels of kynurenic acid and selected proinflammatory cytokines after pharmacological treatment and electroconvulsive therapy (ECT) in patients with depressive disorder

2016 ◽  
Vol 17 (2) ◽  
pp. 75-82 ◽  
Author(s):  
Marcin Olajossy ◽  
Emilia Potembska ◽  
Nikodem Skoczeń ◽  
Bartosz Olajossy ◽  
Ewa Urbańska
Keyword(s):  
Clinical Improvement ◽  
Pharmacological Treatment ◽  
Rating Scale ◽  
Serum Levels ◽  
List Type ◽  
Healthy Controls ◽  
Tnf Α ◽  
Pre Treatment ◽  
The Relationship ◽  
Depressive Patients

AbstractThe aim of the present study was to compare the concentrations of KYNA, 3-OH-KYN and the cytokines TNF-α and IL-6 in patients with depression vs. healthy controls as well as in patients with depression treated pharmacologically vs. those treated using ECT. We also evaluated the relationship between the concentrations of KYNA, 3-OH-KYN and the cytokines TNF-α and IL-6 and clinical improvement measured on the MADRS scale in patients treated pharmacologically and those treated with ECT.Subjects and methods: The study group comprised 29 patients aged 28 to 60 years with a diagnosis of a major depressive episode. Eleven of the patients received pharmacological treatment and 18 were treated with ECT.Patients were assayed for serum levels of KYNA and the cytokines IL-6 and TNF-α. Clinical improvement was measured on the MADRS depression rating scale and the clinical global impression (CGI) scale.Results: Significant differences were found in KYNA levels between depressive patients and healthy controls. Pharmacological treatment significantly contributed to the increase in KYNA levels and ECT – to the increase in TNF-α levels in depressive patients.Conclusions: Depressive patients have significantly lower concentrations of KYNA than healthy individualsDepressive patients who have undergone pharmacological treatment have significantly higher KYNA concentrations than before treatment.Depressive patients who have undergone ECT treatment have significantly lower TNF-α concentrations than before treatment.High pre-treatment levels of IL-6 are associated with a lower MADRS improvement index in pharmacologically treated patients with depression.

562 The clinical improvement of end-stage heart failure is not accompanied by correction of anemia

2006 ◽  
Vol 5 (1) ◽  
pp. 126-126
Author(s):  
S DRAKOS ◽  
E KALDARA ◽  
M BONIOS ◽  
D KARAGEORGOPOULOS ◽  
C PIERRAKOS ◽  
...  
Keyword(s):  
Heart Failure ◽  
Clinical Improvement ◽  
End Stage Heart Failure ◽  
End Stage

Transarterial embolization of peripheral arteriovenous malformations with ethylenevinyl alcohol copolymer - feasibility, technical outcomes, and clinical outcomes

VASA ◽  
2016 ◽  
Vol 45 (6) ◽  
pp. 497-504 ◽  
Author(s):  
Tom De Beule ◽  
Jan Vranckx ◽  
Peter Verhamme ◽  
Veerle Labarque ◽  
Marie-Anne Morren ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Clinical Improvement ◽  
Arteriovenous Malformations ◽  
Clinical Success ◽  
Transarterial Embolization ◽  
Recurrent Bleeding ◽  
Complete Disappearance ◽  
Ethylene Vinyl Alcohol ◽  
Initial Symptoms

Abstract. Background: The technical and clinical outcomes of catheter-directed embolization for peripheral arteriovenous malformations (AVM) using Onyx® (ethylene-vinyl alcohol copolymer) are not well documented. The purpose of this study was to retrospectively assess the safety, technical outcomes and clinical outcomes of catheter-directed Onyx® embolisation for the treatment of symptomatic peripheral AVMs. Patients and methods: Demographics, (pre-)interventional clinical and radiological data were assessed. Follow-up was based on hospital medical records and telephone calls to the patients’ general practitioners. Radiological success was defined as complete angiographic eradication of the peripheral AVM nidus. Clinical success was defined as major clinical improvement or complete disappearance of the initial symptoms. Results: 25 procedures were performed in 22 patients. The principal indications for treatment were pain (n = 10), limb swelling (n = 6), recurrent bleeding (n = 2), tinnitus (n = 3), and exertional dyspnoea (n = 1). Complete radiological success was obtained in eight patients (36 %); near-complete eradication of the nidus was achieved in the remaining 14 patients. Adjunctive embolic agents were used in nine patients (41 %). Clinical success was observed in 18 patients (82%). Major complications were reported in two patients (9 %). During follow-up, seven patients (32 %) presented with symptom recurrence, which required additional therapy in three patients. Conclusions: Catheter-directed embolisation of peripheral AVMs with Onyx® resulted in major clinical improvement or complete disappearance of symptoms in the vast majority of patients, although complete angiographic exclusion of the AVMs occurred in only a minority of patients.

Depressed but Still Moving

2016 ◽  
Vol 24 (4) ◽  
pp. 169-179 ◽  
Author(s):  
Lena K. Jooß ◽  
Lena V. Krämer ◽  
Mary Wyman
Keyword(s):  
Depressive Patients

Abstract. Studies of exercise in depression have not focused on persons already engaging in exercise. The current study aimed to provide an in-depth examination of exercise in depressive persons. In all, 62 depressive outpatients were compared with 62 parallelized nondepressive controls on various aspects of self-reported exercise (total amount, frequency, duration, intensity, type). Of the depressive participants, 52 % and of the nondepressive participants 76 % reported engaging in exercise. Compared with nondepressive exercisers, depressive exercisers exercised less (average total amount of M = 1.7 vs. M = 2.7 hr/week, including all intensity levels), were exercising less frequently (M = 1.7 vs. M = 2.6 sessions/week), and were engaged in fewer different exercise types (M = 1.4 vs. M = 2.0). Groups did not differ in intensity (M = 6.1 vs. 6.2 METs) or duration of exercise sessions (M = 1.1 hr). Exercisers with depression engage in exercise at reduced levels compared with nondepressive exercisers. Interventions to increase exercise in depressive patients should focus on raising the frequency of exercise sessions rather than the duration or intensity.

Agomelatine: Stress and clinical improvement

2013 ◽  
Author(s):  
A. Deschamps Perdomo ◽  
M. J. Sevilla Vicente ◽  
I. Basurte Villamor
Keyword(s):  
Clinical Improvement
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