The influence of light on the development of organs in animals.

2012 ◽  
pp. 425-435
Author(s):  
Jacques Loeb
2020 ◽  
Vol 1 (3) ◽  
pp. 11-17
Author(s):  
P. E. Khodkevich ◽  
K. V. Кulikova ◽  
V. V. Gorev ◽  
I. A. Deev

Over the past decade, an increase in the survival rate of children born with low birth weight, very low birth weight, and extremely low birth weight has been observed in Russian Federation, which is due to transition to new live birth criteria. Premature infants are exposed to a number of adverse factors that have a negative impact on the development of organs and systems, which, in turn, can lead to the occurrence of acute and chronic diseases in various age periods. Therefore, neonatologists and pediatricians are dealing with a new cohort of small children who have particular features of physical and neuropsychological development which may lead to severe debilitating diseases. This review article surveys previous studies evaluating the echographic characteristics of structural and functional development of the urinary, cardiovascular and endocrine systems as a function of body weight at birth and gestational age, and in different age periods.


2021 ◽  
Author(s):  
Carolina Camelo ◽  
Anna Koerte ◽  
Thea Jacobs ◽  
Peter Robin Hiesinger ◽  
Stefan Luschnig

Fusion of endothelial or epithelial tubes is essential for the development of organs like the vertebrate vasculature or the insect tracheal system, but the mechanisms underlying the formation of tubular connections (anastomoses) are not well understood. Tracheal tube fusion in Drosophila is mediated by tip cells that transform into lumenized toroids to connect adjacent tubes. This process depends on the Munc13-4 orthologue Staccato (Stac), which localizes to tip-cell-specific lysosome-related organelles (LROs). We show that tracheal LROs display features of multivesicular bodies (MVBs) and that the tracheal lumen contains membranous extracellular vesicles (EVs), a subset of which carries Stac/Munc13-4 and is associated with tracheal anastomosis sites. The presence of LROs and luminal Stac-EVs depends on the tip-cell-specific GTPase Arl3, suggesting that Stac-EVs derive from fusion of MVBs with the luminal membrane in tip cells during anastomosis formation. The GTPases Rab27 and Rab35 cooperate downstream of Arl3 to promote Stac-MVB formation and tube fusion. We propose that Stac-MVBs act as membrane reservoirs that facilitate lumen fusion in tip cells, in a process regulated by Arl3, Rab27, Rab35, and Stac/Munc13-4.


1955 ◽  
Vol 33 (6) ◽  
pp. 531-533
Author(s):  
Walter Jones

A previously unreported foot rot disease of wallflower, Cheiranthus cheiri, caused by the fungus Phytophthora megasperma, was found in Saanichton, B.C., in 1953. The optimum temperature for growth of the fungus is 20° to 25 °C, the maximum approximately 31 °C, and the minimum below 5 °C. Sporangia develop at all temperatures between 5° and 20 °C, but the optimum temperature for their development is approximately 14 °C, whereas the optimum temperature for the development of organs of fusion is approximately 20 °C. The fungus proved to be pathogenic to wallflower plants only under wet soil conditions, hence it is considered that good soil drainage is an important factor in the control of the disease.


Biomolecules ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 685
Author(s):  
Deviyani Mahajan ◽  
Sudhakar Kancharla ◽  
Prachetha Kolli ◽  
Amarish Kumar Sharma ◽  
Sanjeev Singh ◽  
...  

The extracellular matrix (ECM) plays an important role in the evolution of early metazoans, as it provides structural and biochemical support to the surrounding cells through the cell–cell and cell–matrix interactions. In multi-cellular organisms, ECM plays a pivotal role in the differentiation of tissues and in the development of organs. Fibulins are ECM glycoproteins, found in a variety of tissues associated with basement membranes, elastic fibers, proteoglycan aggregates, and fibronectin microfibrils. The expression profile of fibulins reveals their role in various developmental processes such as elastogenesis, development of organs during the embryonic stage, tissue remodeling, maintenance of the structural integrity of basement membrane, and elastic fibers, as well as other cellular processes. Apart from this, fibulins are also involved in the progression of human diseases such as cancer, cardiac diseases, congenital disorders, and chronic fibrotic disorders. Different isoforms of fibulins show a dual role of tumor-suppressive and tumor-promoting activities, depending on the cell type and cellular microenvironment in the body. Knockout animal models have provided deep insight into their role in development and diseases. The present review covers details of the structural and expression patterns, along with the role of fibulins in embryonic development and disease progression, with more emphasis on their involvement in the modulation of cancer diseases.


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