Dual-Organocatalyst-Promoted Asymmetric Cascade Reaction: Highly Efficient Construction of Enantiopure Fully Substituted Tetrahydro-1,2-oxazines

2014 ◽  
Vol 16 (3) ◽  
pp. 752-755 ◽  
Author(s):  
Hua Lin ◽  
Xing-Wen Sun ◽  
Guo-Qiang Lin
2017 ◽  
Vol 15 (45) ◽  
pp. 9630-9637 ◽  
Author(s):  
Lu Dai ◽  
Yuxuan Hou ◽  
Lvye Zhang ◽  
Zhangtao Chen ◽  
Xiaofei Zeng ◽  
...  

A highly efficient organocatalytic asymmetric aza-Michael-IED/HAD cascade reaction of (E)-ethyl 4-(2-(4-methylphenylsulfonamido)phenyl)-2-oxobut-3-enoate and enals is reported.


2017 ◽  
Vol 139 (36) ◽  
pp. 12736-12744 ◽  
Author(s):  
Yang Hu ◽  
Ke Yu ◽  
Li-Li Shi ◽  
Lei Liu ◽  
Jing-Jing Sui ◽  
...  

Plant Methods ◽  
2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Joan Marquez-Molins ◽  
Jose Antonio Navarro ◽  
Vicente Pallas ◽  
Gustavo Gomez

2020 ◽  
Vol 44 (9) ◽  
pp. 3632-3636
Author(s):  
Sandip Gangadhar Balwe ◽  
Yeon Tae Jeong

The first p-TSA·H2O-catalyzed highly efficient one-pot cascade reaction for the synthesis of novel fused tricyclic benzofuro[2,3-b]pyrroles has been discovered.


ACS Nano ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. 263-271 ◽  
Author(s):  
Kewei Ren ◽  
Yifan Xu ◽  
Ying Liu ◽  
Min Yang ◽  
Huangxian Ju

Synlett ◽  
2019 ◽  
Vol 30 (12) ◽  
pp. 1442-1446 ◽  
Author(s):  
Zhang-qi Lin ◽  
Chao-dong Li ◽  
Zi-chun Zhou ◽  
Shuai Xue ◽  
Jian-rong Gao ◽  
...  

A simple and highly efficient method for the preparation of tetrasubstituted NH-pyrrole from a wide range of chalcones and diethyl iminodiacetates via a Cu(OAc)2-promoted oxidation/[3+2]cycloaddition/aromatization cascade reaction has been developed. This reaction proceeds through dehydrogenations, deamination, and oxidative cyclization, affording the corresponding products in good to excellent yields. This convenient methodology for constructing tetrasubstituted NH-pyrroles has several advantages over existing methods, such as the use of easily accessible chalcones and readily available diethyl iminodiacetates, and mild reaction conditions. A wide range of substrates are tolerated.


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