scholarly journals Recent developments in highly efficient construction of P-stereogenic centers

2020 ◽  
Author(s):  
Xinyi Ye ◽  
Lin Peng ◽  
Xiaoze Bao ◽  
Choon-Hong Tan ◽  
Hong Wang
Keyword(s):  
Highly Efficient ◽  
Stereogenic Centers ◽  
Recent Developments ◽  
Efficient Construction

Convergent Asymmetric Synthesis of a Renin Inhibitor: A Highly Efficient Construction Method of Three Stereogenic Centers

2013 ◽  
Vol 17 (11) ◽  
pp. 1430-1439 ◽  
Author(s):  
Makoto Michida ◽  
Yoshihiro Takayanagi ◽  
Makoto Imai ◽  
Yukito Furuya ◽  
Kenichi Kimura ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Construction Method ◽  
Renin Inhibitor ◽  
Highly Efficient ◽  
Stereogenic Centers ◽  
Efficient Construction

scholarly journals Recent Developments in Polyene Cyclizations and Their Applications in Natural Product Synthesis

Synthesis ◽  
2018 ◽  
Vol 51 (01) ◽  
pp. 67-82 ◽  
Author(s):  
Anthony Barrett ◽  
Tsz-Kan Ma ◽  
Thomas Mies
Keyword(s):  
Transition Metal ◽  
Natural Product ◽  
Lewis Acid ◽  
Multiple Bond ◽  
Natural Product Synthesis ◽  
Cyclization Reactions ◽  
Cascade Cyclizations ◽  
Highly Efficient ◽  
Recent Developments ◽  
Radical Cascade

Cascade polyene cyclization reactions are highly efficient and elegant bioinspired transformations that involve simultaneous multiple bond constructions to rapidly generate complex polycyclic molecules. This review summarizes the most prominent work on a variety of cationic and radical cascade cyclizations and their applications in natural product synthesis published between 2014 and 2018.1 Introduction2 Cationic Polyene Cyclizations2.1 Lewis Acid Mediated Polyene Cyclizations2.2 Brønsted Acid Mediated Polyene Cyclizations2.3 Halogen Electrophile Initiated Polyene Cyclizations2.4 Sulfur Electrophile Initiated Polyene Cyclizations2.5 Transition-Metal-Mediated Cationic Polyene Cyclizations3 Radical Polyene Cyclizations3.1 Transition-Metal-Mediated Radical Polyene Cyclizations3.2 Photocatalyst-Mediated Polyene Cyclizations4 Origin of Stereocontrol in Polyene Cyclizations5 Conclusion

o-(p-Methoxyphenylethynyl)phenyl Glycosides: Versatile New Glycosylation Donors for the Highly Efficient Construction of Glycosidic Linkages

2017 ◽  
Vol 139 (36) ◽  
pp. 12736-12744 ◽  
Author(s):  
Yang Hu ◽  
Ke Yu ◽  
Li-Li Shi ◽  
Lei Liu ◽  
Jing-Jing Sui ◽  
...  
Keyword(s):  
Highly Efficient ◽  
Efficient Construction

scholarly journals NHC-Catalyzed Organocatalytic Asymmetric Approach to 2,2-Disubstituted Benzofuran-3(2H)-ones Containing Fully Substituted Quaternary Stereogenic Center

Catalysts ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 192 ◽  
Author(s):  
Zbigniew Rafiński
Keyword(s):  
Stetter Reaction ◽  
Highly Efficient ◽  
Stereogenic Centers ◽  
Michael Acceptors ◽  
High Yields ◽  
Stereogenic Center ◽  
Quaternary Stereogenic Centers ◽  
Triazolium Salts

A highly efficient and enantioselective approach to the synthesis of functionalized benzofuran-3(2H)-ones is presented. It proceeds via an intramolecular Stetter reaction using β,β-disubstituted Michael acceptors in the construction of five-membered rings with fully-substituted quaternary stereogenic centers and is promoted by terpene-derived triazolium salts. As a result, a series of chiral 2,2-disubstituted benzofuran-3(2H)-one derivatives with linear, branched, and cyclic aliphatic substitutions on the quaternary stereogenic center were obtained in high yields and with excellent enantioselectivities of up to 99% ee.

scholarly journals Highly efficient construction of infectious viroid-derived clones

Plant Methods ◽  
2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Joan Marquez-Molins ◽  
Jose Antonio Navarro ◽  
Vicente Pallas ◽  
Gustavo Gomez
Keyword(s):  
Highly Efficient ◽  
Efficient Construction

scholarly journals Modular continuous flow synthesis of orthogonally protected 6-deoxy glucose glycals

2020 ◽  
Vol 18 (17) ◽  
pp. 3254-3257
Author(s):  
Subbarao Yalamanchili ◽  
Tu-Anh V. Nguyen ◽  
Nicola L. B. Pohl ◽  
Clay S. Bennett
Keyword(s):  
Continuous Flow ◽  
Flow Synthesis ◽  
Highly Efficient ◽  
Efficient Construction ◽  
Commercial Sources

The use of a continuous flow platform for the rapid and highly efficient construction of differentially protected glycals from commercial sources is described.

Phosphine-catalyzed [4+1] annulation of 1,3-(aza)dienes with maleimides: highly efficient construction of azaspiro[4.4]nonenes

2014 ◽  
Vol 50 (88) ◽  
pp. 13506-13509 ◽  
Author(s):  
Mei Yang ◽  
Tianyi Wang ◽  
Shixuan Cao ◽  
Zhengjie He
Keyword(s):  
Highly Efficient ◽  
Efficient Construction
Sign in / Sign up

Export Citation Format

Share Document