Chemical Studies on Mexican Plants Used in Traditional Medicine, XVIII. New Secondary Metabolites from Dodonaea viscosa

1991 ◽  
Vol 54 (3) ◽  
pp. 913-917 ◽  
Author(s):  
Rachel Mata ◽  
José Luis Contreras ◽  
Daniel Crisanto ◽  
Rogelio Pereda-Miranda ◽  
Perla Castañeda ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Dodonaea Viscosa ◽  
Chemical Studies

scholarly journals Volatilome and Essential Oil of Ulomoides dermestoides: A Broad-Spectrum Medical Insect

Molecules ◽  
2021 ◽  
Vol 26 (20) ◽  
pp. 6311
Author(s):  
Paulina J. Cázares-Samaniego ◽  
Claudia G. Castillo ◽  
Miguel A. Ramos-López ◽  
Marco M. González-Chávez
Keyword(s):  
Secondary Metabolites ◽  
Essential Oil ◽  
Essential Oils ◽  
Traditional Medicine ◽  
Broad Spectrum ◽  
Alternative Treatment ◽  
Aromatic Compounds ◽  
Therapeutic Potential ◽  
Pharmacological Interest ◽  
Main Components

Ulomoides dermestoides are used as a broad-spectrum medical insect in the alternative treatment of various diseases. Preliminary volatilome studies carried out to date have shown, as the main components, methyl-1,4-benzoquinone, ethyl-1,4-benzoquinone, 1-tridecene, 1-pentadecene, and limonene. This work focused on the production of metabolites and their metabolic variations in U. dermestoides under stress conditions to provide additional valuable information to help better understand the broad-spectrum medical uses. To this end, VOCs were characterized by HS-SPME with PEG and CAR/PDMS fibers, and the first reported insect essential oils were obtained. In HS-SMPE, we found 17 terpenes, six quinones, five alkenes, and four aromatic compounds; in the essential oils, 53 terpenes, 54 carboxylic acids and derivatives, three alkynes, 12 alkenes (1-Pentadecene, EOT1: 77.6% and EOT2: 57.9%), 28 alkanes, nine alkyl disulfides, three aromatic compounds, 19 alcohols, three quinones, and 12 aldehydes were identified. Between both study approaches, a total of 171 secondary metabolites were identified with no previous report for U. dermestoides. A considerable number of the identified metabolites showed previous studies of the activity of pharmacological interest. Therefore, considering the wide variety of activities reported for these metabolites, this work allows a broader vision of the therapeutic potential of U. dermestoides in traditional medicine.

scholarly journals AGERATUM CONYZOIDES L. (PEMANFAATAN SEBAGAI OBAT DAN BIOAKTIVITASNYA)

2019 ◽  
Vol 11 (3) ◽  
pp. 197
Author(s):  
Marina Silalahi
Keyword(s):  
Fatty Acids ◽  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Wild Plants ◽  
Ageratum Conyzoides ◽  
Comprehensive Information

ABSTRACTAgeratum conyzoides or badotan is a wild plants which uses as traditional medicine. This plant has a distinctive aroma similar to "the smell of goats" so it is called "goatweed". This article aims to explain the use of A. conyzoides as a drug and its bioactivity. The writing of this article is based on the study of literature obtained online and offline including various scientific articles then reviewed and synthesized so as to provide comprehensive information regarding the use of A. conyzoides as traditional medicine. In traditional medicine, Ageratum conyzoides is used as medicine for wounds, ulcers, and fever. Ageratum conyzoides have secondary metabolites such as terpenoids, flavonoids, steroids, terpenes, saponins, fatty acids, and alkaloids, with the main compounds stigmasterol and β-sitosterol. Bioactivity of A. conyzoides are antihistamine, antimicrobial, antiplasmodial, cytoprotective, analgesic, antioxidant and anti diabetes mellitus.Keywords: Ageratum conyzoides, antimicrobial, β-sitosterol, cytoprotective, analgesic. ABSTRAKAgeratum conyzoides atau badotan merupakan salah satu tumbuhan liar yang banyak dimanfaatkan sebagai obat tradisional. Tumbuhan ini memiliki aroma khas mirip dengan “bau kambing” sehingga disebut juga sebagai “goatweed”. Artikel ini bertujuan untuk menjelaskan pemanfaatan A. conyzoides sebagai obat dan bioaktivitasnya. Penulisan artikel ini didasarkan pada kajian literatur yang diperoleh secara online maupun offline meliputi berbagai artikel ilmiah kemudian dikaji dan disintesakan sehingga memberikan informasi yang kompehensif mengenai pemanfaatan A. conyzoides sebagai obat tradisional. Dalam pengobatan tradisional Ageratum conyzoides dimanfaatkan sebagai obat luka, bisul, dan demam. Ageratum conyzoides mengandung metabolit sekunder dari golongan terpenoid, flavonoid, steroid, terpen, senyawa, saponin, asam lemak, dan alkaloid, dengan senyawa utama stigmasterol dan β‐sitosterol. Bioaktivitas yang dimiliki oleh A. conyzoides antara lain sebagai anti histamin, antimikroba, antiplasmodial, sitoprotektif, analgesik, antioksidan dan anti diabetes mellitus.Kata Kunci : Ageratum conyzoides, antimikroba, β‐sitosterol, sitoprotektif, analgesik.

Chemical Studies on Mexican Plants Used in Traditional Medicine, III: New 4-Phenylcoumarins from Exostema caribaeum

1987 ◽  
Vol 50 (5) ◽  
pp. 866-871 ◽  
Author(s):  
Rachel Mata ◽  
Fernando Calzada ◽  
Ma Rosario Garcia ◽  
Ma Teresa Reguero
Keyword(s):  
Traditional Medicine ◽  
Chemical Studies

Anti-Alzheimer's disease activity of secondary metabolites from Xanthoceras sorbifolia Bunge

2020 ◽  
Vol 11 (3) ◽  
pp. 2067-2079
Author(s):  
Wei Li ◽  
Qiuli Lu ◽  
Xiang Li ◽  
Hongcui Liu ◽  
Liangdi Sun ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Secondary Metabolites ◽  
Disease Activity ◽  
Traditional Medicine ◽  
Tree Species ◽  
Edible Oil

Xanthoceras sorbifolia Bunge is an edible oil tree species peculiar to China and it has long been used as a traditional medicine for enuresis in children. In this paper, X. sorbifolia was found to have significant anti-Alzheimer's activity.

scholarly journals Chemical studies on chinese traditional medicine, dangshen. I. Isolation of (Z)-3- and (E)-2-hexenyl .BETA.-D-glucosides.

1988 ◽  
Vol 36 (7) ◽  
pp. 2689-2690 ◽  
Author(s):  
KENJI MIZUTANI ◽  
MASAMICHI YUDA ◽  
OSAMU TANAKA ◽  
YUH-ICHIROU SARUWATARI ◽  
TOHRU FUWA ◽  
...  
Keyword(s):  
Traditional Medicine ◽  
Chinese Traditional Medicine ◽  
Chemical Studies

scholarly journals Phytoconstituents of Genus Micromelum and Their Bioactivity—a Review

2020 ◽  
Vol 15 (5) ◽  
pp. 1934578X2092712
Author(s):  
Tin Myo Thant ◽  
Nanik Siti Aminah ◽  
Alfinda Novi Kristanti ◽  
Rico Ramadhan ◽  
Hnin Thanda Aung ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Bioactive Compounds ◽  
Bioactive Constituents ◽  
Ancient Time ◽  
Leaves And Roots ◽  
New Compounds ◽  
Drug Leads ◽  
Carbazole Alkaloids

The genus Micromelum belongs to the Rutaceae family. As its rich bioactive constituents its stems, flowers, leaves, and roots have been used in traditional medicine, for the treatment of various diseases from ancient time. Phytochemically, many bioactive compounds, including coumarins, polyoxygenated flavonoids, phenylpropanoic acid derivatives, quinolone alkaloids, and also carbazole alkaloids, have been reported as secondary metabolites of the Micromelum spp. including many new compounds. Therefore, Micromelum spp. are considered potential for drug leads. In this article, we present an overview of secondary metabolites isolated from genus Micromelum and their bioactivities that have been reported between 1982 and 2019.

scholarly journals Phytoconstituents of Adenanthera pavonina Linn from the bark extracts

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Arzumand Ara ◽  
Md. Moshfekus Saleh-E-In ◽  
Md. Abul Hashem ◽  
Mesbahuddin Ahmad ◽  
Choudhury Mahmood Hasan
Keyword(s):  
Secondary Metabolites ◽  
Medicinal Plant ◽  
Traditional Medicine ◽  
Spectroscopic Techniques ◽  
Pharmacological Properties ◽  
Adenanthera Pavonina ◽  
Lead Compounds ◽  
Phytochemical Investigation ◽  
Important Medicinal Plant

Abstract Background Adenanthera pavonina L. is an important medicinal plant and its barks are used in traditional medicine for treating different diseases. Therefore, a phytochemical investigation was carried out to isolate and identify secondary metabolites from its barks. Results Seven compounds namely ethyl 3,3-dimethyl-13-hydroxytridecanoate (1), stigmasta-5,22-dien-3β-ol (2), tert.butyl tridecanoate (3), 6-α-hydroxy stigmast-20(21)-en-3-one (4) of dichloromethane extract and 18-(2′, 3′-dihydroxyphenyl)nonadec-17-en-2-ol (5), 1-(N-propyl amino)-2-henecosanone (6), and stigmast–5(6), 20(21)-diene-3-one (7) were isolated from the barks of Adenanthera pavonina Linn. Of these compounds, 1, 4, 5, 6, and 7 appear new. The structures of these compounds were elucidated by spectroscopic techniques, mainly by NMR. Conclusions Five new and two known compounds have been isolated and characterized from the bark of A. pavonina. The isolated compounds could be a potential template for the synthesis and development of new lead compounds with interesting pharmacological properties. Graphical abstract

scholarly journals Callus of American ginseng (Panax quinquefolius) as a source of ginsenosides – medicinal secondary metabolites

2013 ◽  
Vol 50 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Ewa Kochan ◽  
Aleksander Chmiel
Keyword(s):  
North America ◽  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Panax Ginseng ◽  
American Ginseng ◽  
Panax Quinquefolius ◽  
In Vitro Methods ◽  
Derivatives Of ◽  
Active Substances

Abstract:Asian ginseng (Panax ginseng) and American ginseng (P. quinquefolius) are valuable medicinal herbs whose roots have been used for ages in traditional medicine in China and North America as vitalizing and stimulating agents. The roots are obtained mainly from field cultivation, which is a slow (5-7 years long), laborious, and troublesome process; so in vitro methods started to be used to produce ginseng biomass. In our study, non-organogenic callus of P. quinquefolius synthesized the same active substances like field roots, for more than 6 years. The ginsenosides are derivatives of protopanaxadiol (Rb1, Rb2, Rc, Rd) or protopanaxatriol (Rg1, Re). The synthesis of Rg1and Re metabolites is preferred in calli cultured in the dark and with ageing of culture.

New secondary metabolites from Dodonaea viscosa

2014 ◽  
Vol 8 ◽  
pp. 10-15 ◽  
Author(s):  
Ahmad E. Mostafa ◽  
Atef A. El-Hela ◽  
Abd-Elsalam I. Mohammad ◽  
Melissa Jacob ◽  
Stephen J. Cutler ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Dodonaea Viscosa
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