scholarly journals Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

Nano Letters ◽  
2014 ◽  
Vol 14 (4) ◽  
pp. 2181-2188 ◽  
Author(s):  
Ronnie H. Fang ◽  
Che-Ming J. Hu ◽  
Brian T. Luk ◽  
Weiwei Gao ◽  
Jonathan A. Copp ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Coated Nanoparticles

scholarly journals Investigation of an Optical Imaging Platform Integrated with an Ultrasound Application System for In Vitro Verification of Ultrasound-Mediated Drug Delivery

2021 ◽  
Vol 11 (6) ◽  
pp. 2846
Author(s):  
Jong-ryul Choi ◽  
Juyoung Park
Keyword(s):  
Drug Delivery ◽  
Cervical Cancer ◽  
Cell Membrane ◽  
Optical Imaging ◽  
Cancer Cell ◽  
Fluorescent Imaging ◽  
Calcium Flux ◽  
Cervical Cancer Cell ◽  
Application System ◽  
Ultrasound Application

Techniques that increase the permeability of the cell membrane and transfer drugs or genes to cells have been actively developed as effective therapeutic modalities. Also, in line with the development of these drug delivery techniques, the establishment of tools to verify the techniques at the cellular level is strongly required. In this study, we demonstrated an optical imaging platform integrated with an ultrasound application system to verify the feasibility of safe and efficient drug delivery through the cell membrane using ultrasound-microbubble cavitation. To examine the potential of the platform, fluorescence images of both Fura-2 AM and propidium iodide (PI) to measure calcium flux changes and intracellular PI delivery, respectively, during and after the ultrasound-microbubble cavitation in the cervical cancer cell were acquired. Using the optical imaging platform, we determined that calcium flux increased immediately after the ultrasound-microbubble cavitation and were restored to normal levels, and fluorescence signals from intracellular PI increased gradually after the cavitation. The results acquired by the platform indicated that ultrasound-microbubble cavitation can deliver PI into the cervical cancer cell without irreversible damage of the cell membrane. The application of an additional fluorescent imaging module and high-speed imaging modalities can provide further improvement of the performance of this platform. Also, as additional studies in ultrasound instrumentations to measure real-time cavitation signals progress, we believe that the ultrasound-microbubble cavitation-based sonoporation can be employed for safe and efficient drug and gene delivery to various cancer cells.

Cancer-Cell-Membrane-Coated Nanoparticles with a Yolk–Shell Structure Augment Cancer Chemotherapy

Nano Letters ◽  
2019 ◽  
Vol 20 (2) ◽  
pp. 936-946 ◽  
Author(s):  
Di Nie ◽  
Zhuo Dai ◽  
Jialin Li ◽  
Yiwei Yang ◽  
Ziyue Xi ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cancer Cell ◽  
Cancer Chemotherapy ◽  
Shell Structure ◽  
Coated Nanoparticles

Recent advances in mesenchymal stem cell membrane-coated nanoparticles for enhanced drug delivery

2021 ◽  
Author(s):  
Mian Wang ◽  
Yuanfeng Xin ◽  
Hao Cao ◽  
Wanlu Li ◽  
Yifei Hua ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Cell Membrane ◽  
Coated Nanoparticles ◽  
Recent Advances

Studies of nanomedicine have achieved dramatic progress in recent decades.

Co-biomembrane coated Fe3O4/MnO2 multifunctional nanoparticles for targeted delivery and enhanced hemodynamic/photothermal/chemo therapy

2021 ◽  
Author(s):  
Yingshu Guo ◽  
Xiaofei Zheng ◽  
Tingting Gai ◽  
Zhiyong Wei ◽  
Shu-Sheng Zhang
Keyword(s):  
Breast Cancer ◽  
Escherichia Coli ◽  
Drug Delivery ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Targeted Delivery ◽  
Membrane System ◽  
Multifunctional Nanoparticles ◽  
Mcf 7

Here, the co-membrane system of MCF-7 breast cancer cell membrane (MM) and Escherichia coli membrane (EM)-coated Fe3O4/MnO2 multifunctional composite nanoparticles loaded with DOX (Fe3O4/MnO2/MM/EM/D) was used for targeting drug delivery...

scholarly journals Precise Deposition of Polydopamine on Cancer Cell Membrane as Artificial Receptor for Targeted Drug Delivery

iScience ◽  
2020 ◽  
Vol 23 (12) ◽  
pp. 101750
Author(s):  
Hoda Safari Yazd ◽  
Yu Yang ◽  
Long Li ◽  
Lu Yang ◽  
Xiaowei Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Targeted Drug Delivery ◽  
Artificial Receptor ◽  
Targeted Drug

scholarly journals Cell-mediated and cell membrane-coated nanoparticles for drug delivery and cancer therapy

2020 ◽  
Author(s):  
Serkan Yaman ◽  
Uday Chintapula ◽  
Edgar Rodriguez ◽  
Harish Ramachandramoorthy ◽  
Kytai T. Nguyen
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Cell Membrane ◽  
Coated Nanoparticles

Cell membrane-coated nanoparticles as peroxidase mimetics for cancer cell targeted detection and therapy

Talanta ◽  
2021 ◽  
pp. 123071
Author(s):  
Meiling Lian ◽  
Shuaibin Shao ◽  
Meihan Liu ◽  
Yuqing Shi ◽  
Haijun Zhang ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cancer Cell ◽  
Coated Nanoparticles ◽  
Targeted Detection

Cell membrane biomimetic nanoparticles for inflammation and cancer targeting in drug delivery

2020 ◽  
Vol 8 (2) ◽  
pp. 552-568 ◽  
Author(s):  
Huaiji Wang ◽  
Ying Liu ◽  
Ruiqing He ◽  
Dailin Xu ◽  
Jie Zang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Cell Membrane ◽  
Cell Membranes ◽  
Cancer Targeting ◽  
Cell Library ◽  
Coated Nanoparticles ◽  
Biomimetic Nanoparticles

Cell membrane coated nanoparticles have been designed for inflammation and cancer therapy. An array of cell membranes from cell library were extracted and leveraged to coat a variety of nanoparticles for different diseases.

scholarly journals Cancer Cell Membrane‐Coated Nanoparticles for Personalized Therapy in Patient‐Derived Xenograft Models

2019 ◽  
Vol 29 (51) ◽  
pp. 1905671 ◽  
Author(s):  
Lang Rao ◽  
Guang‐Tao Yu ◽  
Qian‐Fang Meng ◽  
Lin‐Lin Bu ◽  
Rui Tian ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cancer Cell ◽  
Personalized Therapy ◽  
Coated Nanoparticles ◽  
Patient Derived Xenograft ◽  
Xenograft Models
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