Gold Nanocages:  Bioconjugation and Their Potential Use as Optical Imaging Contrast Agents

Nano Letters ◽  
2005 ◽  
Vol 5 (3) ◽  
pp. 473-477 ◽  
Author(s):  
Jingyi Chen ◽  
Fusayo Saeki ◽  
Benjamin J. Wiley ◽  
Hu Cang ◽  
Michael J. Cobb ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Optical Imaging ◽  
Gold Nanocages ◽  
Potential Use

scholarly journals Air-Filled Microbubbles Based on Albumin Functionalized with Gold Nanocages and Zinc Phthalocyanine for Multimodal Imaging

Micromachines ◽  
2021 ◽  
Vol 12 (10) ◽  
pp. 1161
Author(s):  
Elizaveta A. Maksimova ◽  
Roman A. Barmin ◽  
Polina G. Rudakovskaya ◽  
Olga A. Sindeeva ◽  
Ekaterina S. Prikhozhdenko ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Physicochemical Parameters ◽  
Multimodal Imaging ◽  
Biomedical Applications ◽  
Zinc Phthalocyanine ◽  
Fluorescence Tomography ◽  
Raster Scanning ◽  
Air Core ◽  
Gold Nanocages ◽  
Potential Use

Microbubbles are intravascular contrast agents clinically used in diagnostic sonography, echocardiography, and radiology imaging applications. However, up to date, the idea of creating microbubbles with multiple functionalities (e.g., multimodal imaging, photodynamic therapy) remained a challenge. One possible solution is the modification of bubble shells by introducing specific compounds responsible for such functions. In the present work, air-core microbubbles with the shell consisting of bovine serum albumin, albumin-coated gold nanocages, and zinc phthalocyanine were prepared using the sonication method. Various physicochemical parameters such as stability over time, size, and concentration were investigated to prove the potential use of these microbubbles as contrast agents. This work shows that hybrid microbubbles have all the necessary properties for multimodal imaging (ultrasound, raster-scanning microscopy, and fluorescence tomography), which demonstrate superior characteristics for potential theranostic and related biomedical applications.

scholarly journals Gold nanocages as contrast agents for photoacoustic imaging

2011 ◽  
Vol 6 (5) ◽  
pp. 370-377 ◽  
Author(s):  
Weiyang Li ◽  
Paige K. Brown ◽  
Lihong V. Wang ◽  
Younan Xia
Keyword(s):  
Contrast Agents ◽  
Photoacoustic Imaging ◽  
Gold Nanocages

scholarly journals Bright and stable near-infrared Pluronic–silica nanoparticles as contrast agents for in vivo optical imaging

2016 ◽  
Vol 4 (33) ◽  
pp. 5560-5566 ◽  
Author(s):  
Lesan Yan ◽  
Huiquan Wang ◽  
Anqi Zhang ◽  
Calvin Zhao ◽  
Yongping Chen ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Contrast Agents ◽  
Optical Imaging ◽  
Silica Nanoparticles ◽  
Near Infrared ◽  
Circulation Time ◽  
In Vivo Optical Imaging

The IR780@NPs exhibited excellent characteristics for in vivo imaging with a long circulation time and high retention in tumor and sentinel lymph node.

scholarly journals Gd- and Eu-Loaded Iron Oxide@Silica Core–Shell Nanocomposites as Trimodal Contrast Agents for Magnetic Resonance Imaging and Optical Imaging

2019 ◽  
Vol 58 (24) ◽  
pp. 16618-16628 ◽  
Author(s):  
Sonia L. C. Pinho ◽  
José Sereno ◽  
Antero J. Abrunhosa ◽  
Marie-Hélène Delville ◽  
João Rocha ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Optical Imaging ◽  
Core Shell ◽  
Resonance Imaging ◽  
Silica Core

Development of fluorescent contrast agents for optical imaging of mouse disease models

2008 ◽  
Author(s):  
J. Kovar ◽  
M. Simpson ◽  
A. Schutz-Geschwender ◽  
X. Xu ◽  
W. M. Volcheck ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Optical Imaging ◽  
Disease Models
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