Synthesis of Amphiphilic Miktoarm Star Copolymers of Poly(n-hexyl isocyanate) and Poly(ethylene glycol) through Reaction with the Active Methylene Group

2008 ◽  
Vol 41 (19) ◽  
pp. 7029-7032 ◽  
Author(s):  
M. Shahinur Rahman ◽  
Mohammad Changez ◽  
Jin-Wook Yoo ◽  
Chi H. Lee ◽  
Shashadhar Samal ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Star Copolymers ◽  
Miktoarm Star ◽  
Poly Ethylene ◽  
Active Methylene ◽  
Methylene Group

Synthesis and pyrolysis of ABC type miktoarm star copolymers with polystyrene, poly(lactic acid) and poly(ethylene glycol) arms

2012 ◽  
Vol 48 (10) ◽  
pp. 1755-1767 ◽  
Author(s):  
Suriye Ozlem ◽  
Birol Iskin ◽  
Gorkem Yilmaz ◽  
Manolya Kukut ◽  
Jale Hacaloglu ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Ethylene Glycol ◽  
Poly Lactic Acid ◽  
Poly Ethylene Glycol ◽  
Star Copolymers ◽  
Miktoarm Star ◽  
Poly Ethylene

Polypeptide–poly(ethylene glycol) miktoarm star copolymers with a fluorescently labeled core: synthesis, delivery and imaging of siRNA

2016 ◽  
Vol 7 (9) ◽  
pp. 1792-1802 ◽  
Author(s):  
Jianbing Huang ◽  
Hui Liang ◽  
Du Cheng ◽  
Jiang Lu
Keyword(s):  
Gene Delivery ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Star Copolymers ◽  
Miktoarm Star ◽  
Poly Ethylene ◽  
Dual Functions

Polypeptide–PEG miktoarm star copolymers with a fluorescently labeled core have been synthesized and exhibit dual functions of gene delivery and bioimaging.

AB2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol) and its electrospun nanofiber blend with poly(ε-caprolactone)

RSC Advances ◽  
2015 ◽  
Vol 5 (46) ◽  
pp. 36715-36726 ◽  
Author(s):  
Bakhshali Massoumi ◽  
Somayeh Davtalab ◽  
Mehdi Jaymand ◽  
Ali Akbar Entezami
Keyword(s):  
Ethylene Glycol ◽  
Electrospun Nanofibers ◽  
Synthesis And Characterization ◽  
Electrospun Nanofiber ◽  
Poly Ethylene Glycol ◽  
Conductive Polyaniline ◽  
Miktoarm Star ◽  
Poly Ethylene ◽  
Type Ab

The aim of this study is the synthesis, and characterization of novel type AB2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol), and preparation of its electrospun nanofibers blend with poly(ε-caprolactone).

RAFT Polymerization of Dual Responsive Hyperbranched-Star Copolymers of Methacrylic Acid and Poly(Ethylene Glycol)

2017 ◽  
Vol 890 ◽  
pp. 78-81 ◽  
Author(s):  
Eduardo C. Atayde Jr. ◽  
Monica M. Berenguel ◽  
Susan D. Arco
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Methacrylic Acid ◽  
Morphological Changes ◽  
Spectroscopic Techniques ◽  
Block Copolymerization ◽  
Poly Ethylene Glycol ◽  
Dual Responsive ◽  
Star Copolymers ◽  
Poly Ethylene

Smart polymers are materials that respond to external stimuli via reversible morphological changes, making them potential systems for drug delivery applications. In this study, dual-responsive star copolymers with a hyperbranched core composed of ethylene glycol dimethacrylate (EGDMA) - methacrylic acid (MAA) and poly(ethylene glycol) methyl ether methacrylate (PEGMA) arms were synthesized via two-step Reversible Addition-fragmentation Chain Transfer (RAFT) block copolymerization. The synthesis involved the formation of the hyperbranched MAA core followed by arm extension with PEGMA. The formation of the hyperbranched core and subsequent copolymerization with PEGMA were verified by FT-IR and 1H-NMR spectroscopic techniques. The distinct EGDMA peak was found at 4.3 ppm while the peak attributed to PEGMA was found at around 3.5 ppm. Furthermore, the synthesized block copolymers were both temperature and pH-responsive with LCST value at 57°C and morphological transition at pH 5.6. The synthesized smart polymer was also biocompatible based on Trypan blue cytotoxicity assay. The inherent dual responsive behavior and biocompatibility of the copolymer render it a good candidate for drug delivery systems.

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