Crystallization-Driven Solution Self-Assembly of μ-ABC Miktoarm Star Terpolymers with Core-Forming Polyferrocenylsilane Blocks

2014 ◽  
Vol 47 (23) ◽  
pp. 8420-8428 ◽  
Author(s):  
Adam Nunns ◽  
George R. Whittell ◽  
Mitchell A. Winnik ◽  
Ian Manners
Keyword(s):  
Self Assembly ◽  
Miktoarm Star

A Novel Photoresponsive Azobenzene-Containing Miktoarm Star Polymer: Self-Assembly and Photoresponse Properties

2014 ◽  
Vol 47 (11) ◽  
pp. 3693-3700 ◽  
Author(s):  
Eva Blasco ◽  
Bernhard V. K. J. Schmidt ◽  
Christopher Barner-Kowollik ◽  
Milagros Piñol ◽  
Luis Oriol
Keyword(s):  
Self Assembly ◽  
Star Polymer ◽  
Miktoarm Star

Synthesis of miktoarm star amphiphilic block copolymers via combination of NMRP and ATRP and investigation on self-assembly behaviors

2009 ◽  
Vol 47 (22) ◽  
pp. 6304-6315 ◽  
Author(s):  
Weidong Zhang ◽  
Wei Zhang ◽  
Nianchen Zhou ◽  
Jian Zhu ◽  
Zhenping Cheng ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Self Assembly ◽  
Amphiphilic Block Copolymers ◽  
Miktoarm Star

Miktoarm star polymers via cyclodextrin-driven supramolecular self-assembly

2012 ◽  
Vol 3 (11) ◽  
pp. 3064 ◽  
Author(s):  
Bernhard V. K. J. Schmidt ◽  
Martin Hetzer ◽  
Helmut Ritter ◽  
Christopher Barner-Kowollik
Keyword(s):  
Self Assembly ◽  
Star Polymers ◽  
Miktoarm Star

scholarly journals Miktoarm Star Polymers: Branched Architectures in Drug Delivery

Pharmaceutics ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 827 ◽  
Author(s):  
Victor Lotocki ◽  
Ashok Kakkar
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Polymeric Nanoparticles ◽  
Drug Loading ◽  
Therapeutic Interventions ◽  
Structure Property ◽  
Sustained Drug Release ◽  
Amphiphilic Macromolecules ◽  
Miktoarm Star ◽  
Core Junction

Delivering active pharmaceutical agents to disease sites using soft polymeric nanoparticles continues to be a topical area of research. It is becoming increasingly evident that the composition of amphiphilic macromolecules plays a significant role in developing efficient nanoformulations. Branched architectures with asymmetric polymeric arms emanating from a central core junction have provided a pivotal venue to tailor their key parameters. The build-up of miktoarm stars offers vast polymer arm tunability, aiding in the development of macromolecules with adjustable properties, and allows facile inclusion of endogenous stimulus-responsive entities. Miktoarm star-based micelles have been demonstrated to exhibit denser coronae, very low critical micelle concentrations, high drug loading contents, and sustained drug release profiles. With significant advances in chemical methodologies, synthetic articulation of miktoarm polymer architecture, and determination of their structure-property relationships, are now becoming streamlined. This is helping advance their implementation into formulating efficient therapeutic interventions. This review brings into focus the important discoveries in the syntheses of miktoarm stars of varied compositions, their aqueous self-assembly, and contributions their formulations are making in advancing the field of drug delivery.

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