pH-responsive ABC type miktoarm star terpolymers: Synthesis via combination of click reaction and SET-LRP, characterization, self-assembly, and controlled drug release

Polymer ◽  
2015 ◽  
Vol 66 ◽  
pp. 179-191 ◽  
Author(s):  
Raouf Alizadeh ◽  
Mousa Ghaemy
Keyword(s):  
Drug Release ◽  
Self Assembly ◽  
Click Reaction ◽  
Controlled Drug Release ◽  
Ph Responsive ◽  
Miktoarm Star

Self assembly and controlled drug release of a nano-laminated graphite carbon nitride/methotrexate complex

2018 ◽  
Vol 29 (8) ◽  
Author(s):  
Shanshan Liu ◽  
Zhaoliang Guo ◽  
Xiongfeng Zeng ◽  
Xianguang Meng ◽  
Haina Sun ◽  
...  
Keyword(s):  
Drug Release ◽  
Self Assembly ◽  
Carbon Nitride ◽  
Controlled Drug Release

scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Core Shell ◽  
Assembly Process ◽  
Block Polymer ◽  
Hollow Mesoporous Silica

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

scholarly journals Carbon Nano-Onions Reinforced Multilayered Thin Film System for Stimuli-Responsive Drug Release

Pharmaceutics ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1208
Author(s):  
Narsimha Mamidi ◽  
Ramiro Velasco Delgadillo ◽  
Aldo Gonzáles Ortiz ◽  
Enrique Barrera
Keyword(s):  
Thin Film ◽  
Thin Films ◽  
Drug Release ◽  
Self Assembly ◽  
Critical Role ◽  
Layer By Layer ◽  
Film System ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Thin Film System

Herein, poly (N-(4-aminophenyl) methacrylamide))-carbon nano-onions (PAPMA-CNOs = f-CNOs) and anilinated-poly (ether ether ketone) (AN-PEEK) have synthesized, and AN-PEEK/f-CNOs composite thin films were primed via layer-by-layer (LbL) self-assembly for stimuli-responsive drug release. The obtained thin films exhibited pH-responsive drug release in a controlled manner; pH 4.5 = 99.2% and pH 6.5 = 59.3% of doxorubicin (DOX) release was observed over 15 days. Supramolecular π-π stacking interactions between f-CNOs and DOX played a critical role in controlling drug release from thin films. Cell viability was studied with human osteoblast cells and augmented viability was perceived. Moreover, the thin films presented 891.4 ± 8.2 MPa of the tensile strength (σult), 43.2 ± 1.1 GPa of Young’s modulus (E), and 164.5 ± 1.7 Jg−1 of toughness (K). Quantitative scrutiny revealed that the well-ordered aligned nanofibers provide critical interphase, and this could be responsible for augmented tensile properties. Nonetheless, a pH-responsive and mechanically robust biocompatible thin-film system may show potential applications in the biomedical field.

Voltage-responsive reversible self-assembly and controlled drug release of ferrocene-containing polymeric superamphiphiles

Soft Matter ◽  
2015 ◽  
Vol 11 (38) ◽  
pp. 7494-7501 ◽  
Author(s):  
Xueyi Chang ◽  
Zhiyu Cheng ◽  
Biye Ren ◽  
Renfeng Dong ◽  
Jun Peng ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Drug Release ◽  
Acrylic Acid ◽  
Self Assembly ◽  
Electrostatic Interactions ◽  
Controlled Drug Release ◽  
Poly Ethylene Glycol ◽  
Block Polymer ◽  
Poly Ethylene ◽  
Oppositely Charged

A voltage-responsive comb-like superamphiphilic block polymer PEG113-b-PAA30/FTMA was prepared based on the electrostatic interactions of a ferrocenyl surfactant (FTMA) and an oppositely charged poly-(ethylene glycol)-b-poly(acrylic acid) (PEG113-b-PAA30) in aqueous solution.

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