Free-Standing Lipid Bilayers in Silicon Chips−Membrane Stabilization Based on Microfabricated Apertures with a Nanometer-Scale Smoothness

Langmuir ◽  
2010 ◽  
Vol 26 (3) ◽  
pp. 1949-1952 ◽  
Author(s):  
Ayumi Hirano-Iwata ◽  
Kouji Aoto ◽  
Azusa Oshima ◽  
Tasuku Taira ◽  
Ryo-taro Yamaguchi ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Nanometer Scale ◽  
Membrane Stabilization ◽  
Free Standing ◽  
Silicon Chips

Mechanically Stable Lipid Bilayers in Teflon-Coated Silicon Chips for Single-Channel Recordings

2012 ◽  
Vol 4 (1) ◽  
pp. 2-7 ◽  
Author(s):  
Azusa Oshima ◽  
Ayumi Hirano-Iwata ◽  
Tomohiro Nasu ◽  
Yasuo Kimura ◽  
Michio Niwano
Keyword(s):  
Lipid Bilayers ◽  
Single Channel ◽  
Single Channel Recordings ◽  
Silicon Chips

Using Bicellar Mixtures To Form Supported and Suspended Lipid Bilayers on Silicon Chips

Langmuir ◽  
2006 ◽  
Vol 22 (19) ◽  
pp. 8163-8168 ◽  
Author(s):  
Reema Zeineldin ◽  
Julie A. Last ◽  
Andrea L. Slade ◽  
Linnea K. Ista ◽  
Paul Bisong ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Silicon Chips

Nanopore Arrays for Stable and Functional Free-Standing Lipid Bilayers

2007 ◽  
Vol 19 (24) ◽  
pp. 4466-4470 ◽  
Author(s):  
X. Han ◽  
A. Studer ◽  
H. Sehr ◽  
I. Geissbühler ◽  
M. Di Berardino ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Free Standing ◽  
Nanopore Arrays

scholarly journals Supramolecular architectures of molecularly thin yet robust free-standing layers

2019 ◽  
Vol 5 (2) ◽  
pp. eaav4489 ◽  
Author(s):  
Mina Moradi ◽  
Nadia L. Opara ◽  
Ludovico G. Tulli ◽  
Christian Wäckerlin ◽  
Scott J. Dalgarno ◽  
...  
Keyword(s):  
Self Assembly ◽  
Electronic Devices ◽  
Nanometer Scale ◽  
Electron Radiation ◽  
Free Standing ◽  
Supramolecular Architectures ◽  
Wide Range ◽  
Noncovalent Bonds ◽  
Monomolecular Layers ◽  
Molecular Layers

Stable, single-nanometer thin, and free-standing two-dimensional layers with controlled molecular architectures are desired for several applications ranging from (opto-)electronic devices to nanoparticle and single-biomolecule characterization. It is, however, challenging to construct these stable single molecular layers via self-assembly, as the cohesion of those systems is ensured only by in-plane bonds. We herein demonstrate that relatively weak noncovalent bonds of limited directionality such as dipole-dipole (–CN⋅⋅⋅NC–) interactions act in a synergistic fashion to stabilize crystalline monomolecular layers of tetrafunctional calixarenes. The monolayers produced, demonstrated to be free-standing, display a well-defined atomic structure on the single-nanometer scale and are robust under a wide range of conditions including photon and electron radiation. This work opens up new avenues for the fabrication of robust, single-component, and free-standing layers via bottom-up self-assembly.

Focused Ion-Beam Based Nanohole Modeling, Simulation, Fabrication, and Application

2010 ◽  
Vol 132 (1) ◽  
Author(s):  
Jack Zhou ◽  
Guoliang Yang
Keyword(s):  
Thin Film ◽  
Focused Ion Beam ◽  
Electrochemical Etching ◽  
Ion Beam ◽  
Machining Process ◽  
Nanometer Scale ◽  
Free Standing ◽  
Single Digit ◽  
Epitaxial Deposition ◽  
And Control

There are three major steps toward the fabrication of a single-digit nanohole: (1) preparing the free-standing thin film by epitaxial deposition and electrochemical etching, (2) making submicron holes (0.2–0.02 μm) by focused ion beam (FIB), and (3) reducing the hole to less than 10 nm by FIB-induced deposition. One specific aim for this paper is to model, simulate, and control the focused ion-beam machining process to fabricate holes that can reach a single-digit nanometer scale on solid-state thin films. Preliminary work has been done on the thin film (30 nm in thickness) preparation, submicron hole fabrication, and ion-beam-induced deposition, and the results are presented.

Improved stability of free-standing lipid bilayers based on nanoporous alumina films

2010 ◽  
Vol 96 (21) ◽  
pp. 213706 ◽  
Author(s):  
Ayumi Hirano-Iwata ◽  
Tasuku Taira ◽  
Azusa Oshima ◽  
Yasuo Kimura ◽  
Michio Niwano
Keyword(s):  
Lipid Bilayers ◽  
Free Standing ◽  
Nanoporous Alumina ◽  
Alumina Films ◽  
Improved Stability

Measurement of membrane tension of free standing lipid bilayers via laser-induced surface deformation spectroscopy

Soft Matter ◽  
2015 ◽  
Vol 11 (44) ◽  
pp. 8641-8647 ◽  
Author(s):  
Tomohiko Takei ◽  
Tatsuya Yaguchi ◽  
Takuya Fujii ◽  
Tomonori Nomoto ◽  
Taro Toyota ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Lipid Membranes ◽  
Surface Deformation ◽  
Membrane Tension ◽  
Free Standing ◽  
Black Lipid Membranes ◽  
Non Invasive ◽  
Invasive Measurement

Non-invasive measurement of the membrane tension of free-standing black lipid membranes (BLMs), with sensitivity on the order of μN m−1, was achieved using laser-induced surface deformation (LISD) spectroscopy.

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