scholarly journals Ultrasmall, Water-Soluble Magnetite Nanoparticles with High Relaxivity for Magnetic Resonance Imaging

2009 ◽  
Vol 113 (49) ◽  
pp. 20855-20860 ◽  
Author(s):  
Fengqin Hu ◽  
Keith W. MacRenaris ◽  
Emily A. Waters ◽  
Taiyang Liang ◽  
Elise A. Schultz-Sikma ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetite Nanoparticles ◽  
Water Soluble ◽  
Resonance Imaging ◽  
High Relaxivity

Water-Soluble Superparamagnetic Magnetite Nanoparticles with Biocompatible Coating for Enhanced Magnetic Resonance Imaging

ACS Nano ◽  
2011 ◽  
Vol 5 (8) ◽  
pp. 6315-6324 ◽  
Author(s):  
Lisong Xiao ◽  
Jiangtian Li ◽  
Dermot F. Brougham ◽  
Eoin K. Fox ◽  
Neus Feliu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Magnetite Nanoparticles ◽  
Water Soluble ◽  
Resonance Imaging ◽  
Biocompatible Coating

scholarly journals A Gadolinium(III) Complex Based on the Thymine Nucleobase with Properties Suitable for Magnetic Resonance Imaging

2021 ◽  
Vol 22 (9) ◽  
pp. 4586
Author(s):  
Marta Orts-Arroyo ◽  
Amadeo Ten-Esteve ◽  
Sonia Ginés-Cárdenas ◽  
Isabel Castro ◽  
Luis Martí-Bonmatí ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Lesion Detection ◽  
Resonance Imaging ◽  
X Ray Diffraction ◽  
Functional Images ◽  
High Relaxivity ◽  
Contrast Enhanced ◽  
Phantom Studies

The paramagnetic gadolinium(III) ion is used as contrast agent in magnetic resonance (MR) imaging to improve the lesion detection and characterization. It generates a signal by changing the relaxivity of protons from associated water molecules and creates a clearer physical distinction between the molecule and the surrounding tissues. New gadolinium-based contrast agents displaying larger relaxivity values and specifically targeted might provide higher resolution and better functional images. We have synthesized the gadolinium(III) complex of formula [Gd(thy)2(H2O)6](ClO4)3·2H2O (1) [thy = 5-methyl-1H-pyrimidine-2,4-dione or thymine], which is the first reported compound based on gadolinium and thymine nucleobase. 1 has been characterized through UV-vis, IR, SEM-EDAX, and single-crystal X-ray diffraction techniques, and its magnetic and relaxometric properties have been investigated by means of SQUID magnetometer and MR imaging phantom studies, respectively. On the basis of its high relaxivity values, this gadolinium(III) complex can be considered a suitable candidate for contrast-enhanced magnetic resonance imaging.

Monodisperse water-soluble Fe–Ni nanoparticles for magnetic resonance imaging

2011 ◽  
Vol 509 (4) ◽  
pp. 1217-1221 ◽  
Author(s):  
Hong Yang ◽  
Xuejian Li ◽  
Hong Zhou ◽  
Yeming Zhuang ◽  
He Hu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Water Soluble ◽  
Ni Nanoparticles ◽  
Resonance Imaging
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