Conformational Landscape of (R,R)-Pterocarpans with Biological Activity in Vacuo and in Aqueous Solution (PCM and/or Water Clusters)†

2006 ◽  
Vol 110 (2) ◽  
pp. 647-659 ◽  
Author(s):  
Giuliano Alagona ◽  
Caterina Ghio
Keyword(s):  
Aqueous Solution ◽  
Biological Activity ◽  
Water Clusters ◽  
Conformational Landscape

Simulation of UV Absorption Spectra and Relaxation Dynamics of Uracil and Uracil-Water Clusters

2020 ◽  
Author(s):  
Branislav Milovanović ◽  
Jurica Novak ◽  
Mihajlo Etinski ◽  
Wolfgang Domcke ◽  
Nadja Doslic
Keyword(s):  
Aqueous Solution ◽  
Gas Phase ◽  
Absorption Spectra ◽  
Absorption Spectroscopy ◽  
Water Clusters ◽  
Uv Absorption ◽  
Relaxation Dynamics ◽  
Nonradiative Relaxation ◽  
Uv Absorption Spectra ◽  
Uv Absorption Spectroscopy

Despite many studies, the mechanisms of nonradiative relaxation of uracil in the gas phase and in aqueous solution are still not fully resolved. Here we combine theoretical UV absorption spectroscopy...

THE DEVELOPMENT OF A RADIOIMMUNOASSAY FOR OXYTOCIN: SENSITIVITY OF THE ASSAY IN AQUEOUS BUFFER SOLUTION, SPECIFICITY AND THE DISSOCIATION OF IMMUNOLOGICAL AND BIOLOGICAL ACTIVITY

1970 ◽  
Vol 46 (4) ◽  
pp. 533-542 ◽  
Author(s):  
T. CHARD ◽  
M. L. FORSLING ◽  
M. A. R. JAMES ◽  
M. J. KITAU ◽  
J. LANDON
Keyword(s):  
Aqueous Solution ◽  
Biological Activity ◽  
Arginine Vasopressin ◽  
Late Pregnancy ◽  
Reducing Agents ◽  
Immunological Activity ◽  
Buffer Solution ◽  
Aqueous Buffer ◽  
Lysine Vasopressin ◽  
Other Substances

SUMMARY A radioimmunoassay for oxytocin in aqueous solution is described, with a sensitivity comparable with the best current bioassays. It is highly specific; arginine-vasopressin and lysine-vasopressin interfere only at 1000-fold greater concentration, while bradykinin, histamine, acetycholine and many other substances, which interfere with some bioassays, have no effect. In certain circumstances, there is a dissociation between loss of biological and immunological activity. Thus reducing agents had no effect on immunological activity, in contrast to their effect on biological activity. In late pregnancy plasma, the biological activity of oxytocin is destroyed more rapidly than the immunological activity. Radioimmunoassays have considerable advantages over bioassays both in convenience and specificity. However, bioassays should be employed for reference purposes because of the dissociation between biological and immunological activity that may occur.

X-ray Scattering from Immunostimulatory Tetrapod-Shaped DNA in Aqueous Solution To Explore Its Biological Activity–Conformation Relationship

2014 ◽  
Vol 118 (35) ◽  
pp. 10373-10379 ◽  
Author(s):  
Yusuke Sanada ◽  
Shunsuke Sakamoto ◽  
Tomoki Shiomi ◽  
Tadashi Okobira ◽  
Efstratios Mylonas ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Biological Activity ◽  
X Ray ◽  
X Ray Scattering ◽  
Ray Scattering

Weitere Untersuchungen zur Aminosäuresequenz des Melittins

1969 ◽  
Vol 24 (1) ◽  
pp. 33-35 ◽  
Author(s):  
Joachim Jentsch
Keyword(s):  
Aqueous Solution ◽  
Molecular Weight ◽  
Biological Activity ◽  
Amino Acid ◽  
Amino Acid Sequence ◽  
Polypeptide Chain ◽  
Optical Rotatory Dispersion ◽  
Optical Rotatory ◽  
Surface Active ◽  
Α Helix

Melittin is the (main) toxic peptide of bee venom having a molecular weight of 2840, with a known sequence (s. fig. 1). Optical rotatory dispersion of non-crystalline melittin in aqueous solution suggests that the polypeptide chain is random, although 7% α-helix has been determined. These results are in agreement with the amino acid sequence of melittin and the assumption that the biological activity is attributable to its surface active character.

Hydration of Fe+: A Monte Carlo simulation of water clusters and of a dilute aqueous solution

1988 ◽  
Vol 9 (8) ◽  
pp. 819-826 ◽  
Author(s):  
A. González-Lafont ◽  
J. M. Lluch ◽  
A. Oliva ◽  
J. Bertrán
Keyword(s):  
Aqueous Solution ◽  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Water Clusters ◽  
Dilute Aqueous Solution

scholarly journals Photodegradation of fluorene in aqueous solution: Identification and biological activity testing of degradation products

2016 ◽  
Vol 1442 ◽  
pp. 118-128 ◽  
Author(s):  
Said Kinani ◽  
Yasmine Souissi ◽  
Aziz Kinani ◽  
Svetlana Vujović ◽  
Sélim Aït-Aïssa ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Biological Activity ◽  
Degradation Products
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