Reductive Carbonylation of Aryl Halides Employing a Two-Chamber Reactor: A Protocol for the Synthesis of Aryl Aldehydes Including13C- and D-Isotope Labeling

2013 ◽  
Vol 78 (12) ◽  
pp. 6112-6120 ◽  
Author(s):  
Signe Korsager ◽  
Rolf H. Taaning ◽  
Anders T. Lindhardt ◽  
Troels Skrydstrup
Keyword(s):  
Isotope Labeling ◽  
Aryl Halides ◽  
Aryl Aldehydes ◽  
Reductive Carbonylation

Copper ferrite catalyst for direct arylation of acidic C-H bonds in azoles with aryl aldehydes

2021 ◽  
Vol 10 (4) ◽  
pp. 64-68
Author(s):  
Cuong Vu Minh ◽  
Anh Nguyen Thai ◽  
Nam Phan Thanh Son ◽  
Tung Nguyen Thanh
Keyword(s):  
Functional Groups ◽  
Aryl Halides ◽  
Copper Ferrite ◽  
Coupling Reagents ◽  
Direct Arylation ◽  
Aryl Aldehydes ◽  
Benzaldehyde Derivatives

Coupling reagents toward direct arylation of C2-H bonds in aryl azoles are often limited to aryl halides. Herein we report a functionalization of the acidic sp2 C-H bonds in benzothiazoles with benzaldehyde derivatives. Reactions proceeded in the presence of commercially ready CuFe2O4 catalyst. Scope of functional groups included chloro, nitro, cyano, and ester groups.

Palladium-catalysed reductive carbonylation of aryl halides with iron pentacarbonyl for synthesis of aromatic aldehydes and deuterated aldehydes

2015 ◽  
Vol 29 (11) ◽  
pp. 719-724 ◽  
Author(s):  
Nasser Iranpoor ◽  
Habib Firouzabadi ◽  
Elham Etemadi-Davan ◽  
Abed Rostami ◽  
Khashayar Rajabi Moghadam
Keyword(s):  
Aromatic Aldehydes ◽  
Iron Pentacarbonyl ◽  
Aryl Halides ◽  
Reductive Carbonylation

Hydroformylation of olefins and reductive carbonylation of aryl halides with syngas formed ex situ from dehydrogenative decarbonylation of hexane-1,6-diol

2015 ◽  
Vol 13 (3) ◽  
pp. 938-945 ◽  
Author(s):  
Stig Holden Christensen ◽  
Esben P. K. Olsen ◽  
Jascha Rosenbaum ◽  
Robert Madsen
Keyword(s):  
Carbon Monoxide ◽  
Molecular Hydrogen ◽  
Aryl Halides ◽  
Ex Situ ◽  
Reductive Carbonylation

Carbon monoxide and molecular hydrogen are liberated from hexane-1,6-diol in a two-chamber reactor and employed for either a hydroformylation of olefins or a reductive carbonylation of aryl halides.

ChemInform Abstract: Palladium-Catalyzed Reductive Carbonylation of Aryl Halides with Iron Pentacarbonyl for Synthesis of Aromatic Aldehydes and Deuterated Aldehydes.

ChemInform ◽  
2016 ◽  
Vol 47 (13) ◽  
pp. no-no
Author(s):  
Nasser Iranpoor ◽  
Habib Firouzabadi ◽  
Elham Etemadi-Davan ◽  
Abed Rostami ◽  
Khashayar Rajabi Moghadam
Keyword(s):  
Aromatic Aldehydes ◽  
Iron Pentacarbonyl ◽  
Aryl Halides ◽  
Reductive Carbonylation ◽  
Palladium Catalyzed

Pd-Catalyzed Reductive Carbonylation-Ring Closure of Aryl Halides: A Direct Approach for Synthesis of Benzimidazoles

2016 ◽  
Vol 1 (15) ◽  
pp. 4418-4422 ◽  
Author(s):  
Elham Etemadi-Davan ◽  
Nasser Iranpoor ◽  
Dariush Khalili
Keyword(s):  
Aryl Halides ◽  
Ring Closure ◽  
Direct Approach ◽  
Reductive Carbonylation

Palladium-Catalyzed Reductive Carbonylation of Aryl Halides withN-Formylsaccharin as a CO Source

2013 ◽  
Vol 125 (33) ◽  
pp. 8773-8777 ◽  
Author(s):  
Tsuyoshi Ueda ◽  
Hideyuki Konishi ◽  
Kei Manabe
Keyword(s):  
Aryl Halides ◽  
Reductive Carbonylation ◽  
Palladium Catalyzed

scholarly journals Rhodium-catalyzed reductive carbonylation of aryl iodides to arylaldehydes with syngas

2020 ◽  
Vol 16 ◽  
pp. 645-656 ◽  
Author(s):  
Zhenghui Liu ◽  
Peng Wang ◽  
Zhenzhong Yan ◽  
Suqing Chen ◽  
Dongkun Yu ◽  
...  
Keyword(s):  
Reaction Mechanism ◽  
Industrial Applications ◽  
Catalytic Method ◽  
Broad Application ◽  
Aryl Aldehydes ◽  
Mild Conditions ◽  
Aryl Iodides ◽  
Reductive Carbonylation ◽  
Experimental Parameters ◽  
Application Prospects

The reductive carbonylation of aryl iodides to aryl aldehydes possesses broad application prospects. We present an efficient and facile Rh-based catalytic system composed of the commercially available Rh salt RhCl3·3H2O, PPh3 as phosphine ligand, and Et3N as the base, for the synthesis of arylaldehydes via the reductive carbonylation of aryl iodides with CO and H2 under relatively mild conditions with a broad substrate range affording the products in good to excellent yields. Systematic investigations were carried out to study the experimental parameters. We explored the optimal ratio of Rh salt and PPh3 ligand, substrate scope, carbonyl source and hydrogen source, and the reaction mechanism. Particularly, a scaled-up experiment indicated that the catalytic method could find valuable applications in industrial productions. The low gas pressure, cheap ligand and low metal dosage could significantly improve the practicability in both chemical researches and industrial applications.

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