In Situ Formation ofN-Trifluoroacetoxy Succinimide (TFA-NHS): One-Pot Formation of Succinimidyl Esters,N-Trifluoroacetyl Amino Acid Succinimidyl Esters, andN-Maleoyl Amino Acid Succinimidyl Esters

2011 ◽  
Vol 76 (21) ◽  
pp. 9169-9174 ◽  
Author(s):  
Nicholas M. Leonard ◽  
Jarmila Brunckova
Keyword(s):  
Amino Acid ◽  
One Pot ◽  
In Situ Formation

A facile one pot route for the synthesis of imide tethered peptidomimetics

2016 ◽  
Vol 14 (2) ◽  
pp. 556-563 ◽  
Author(s):  
Veladi Panduranga ◽  
Girish Prabhu ◽  
Roopesh Kumar ◽  
Basavaprabhu Basavaprabhu ◽  
Vommina V. Sureshbabu
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Efficient Method ◽  
One Pot ◽  
Protected Amino Acid

A simple and efficient method for the synthesis of N,N’-orthogonally protected imide tethered peptidomimetics is presented. The imide peptidomimetics were synthesized by coupling the in situ generated selenocarboxylate of Nα-protected amino acids with Nα-protected amino acid azides in good yields.

scholarly journals Visible Light-Promoted Amide Bond Formation via One-Pot Nitrone in Situ Formation/Rearrangement Cascade

CCS Chemistry ◽  
2020 ◽  
pp. 2764-2771
Author(s):  
Bao-Gui Cai ◽  
Shuai-Shuai Luo ◽  
Lin Li ◽  
Lei Li ◽  
Jun Xuan ◽  
...  
Keyword(s):  
Visible Light ◽  
Bond Formation ◽  
Amide Bond ◽  
One Pot ◽  
Amide Bond Formation ◽  
In Situ Formation

Expeditious Scalable Catalyst-Free One-Pot Synthesis of 4-Alkoxy-5-amino-3-methylthiophene-2-carbonitriles via Sequential Reactions­ of Lithiated Alkoxyallenes with Isothiocyanates and 2-Bromoacetonitrile

Synthesis ◽  
2018 ◽  
Vol 50 (09) ◽  
pp. 1891-1900 ◽  
Author(s):  
Nina Nedolya ◽  
Boris Trofimov ◽  
Olga Tarasova ◽  
Alexander Albanov
Keyword(s):  
Intramolecular Cyclization ◽  
Thiophene Ring ◽  
One Pot ◽  
One Pot Synthesis ◽  
Convenient Approach ◽  
Reaction Proceeds ◽  
Sequential Addition ◽  
In Situ Formation ◽  
Cyano Groups

A synthetically simple and convenient approach to tetrasubstituted thiophenes with rare combination of the alkoxy, amino, and cyano groups has been developed. The assembly of polyfunctionalized thiophene ring is implemented in one preparative step by sequential addition of isothiocyanate and 2-bromoacetonitrile to the lithiated (with n-BuLi) alkoxyallene. The reaction proceeds through in situ formation and intramolecular cyclization of cyanomethyl 2-alkoxy-N-buta-2,3-dienimidothioate (1-aza-1,3,4-triene).

“One-Pot” In Situ Formation of Gold Nanoparticles within Poly(acrylamide) Hydrogels

2013 ◽  
Vol 214 (10) ◽  
pp. 1114-1121 ◽  
Author(s):  
Natalya Dolya ◽  
Oscar Rojas ◽  
Sabine Kosmella ◽  
Brigitte Tiersch ◽  
Joachim Koetz ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
One Pot ◽  
In Situ Formation ◽  
Poly Acrylamide

scholarly journals One-Pot NBS-Promoted Synthesis of Imidazoles and Thiazoles from Ethylarenes in Water

Molecules ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 893 ◽  
Author(s):  
Liang Chen ◽  
Huajian Zhu ◽  
Jiang Wang ◽  
Hong Liu
Keyword(s):  
One Pot ◽  
Metal Free ◽  
Reaction Proceeds ◽  
In Situ Formation

A facile and eco-friendly method has been developed for the synthesis of imidazoles and thiazoles from ethylarenes in water. The reaction proceeds via in situ formation of α-bromoketone using NBS as a bromine source as well as an oxidant, followed by trapping with suitable nucleophiles to provide the corresponding products in good yields under metal-free conditions.

In situ formation of vinylboranes for use in Diels Alder reactions. An easy one-pot Diels-Alder synthesis of cyclohexenols

1992 ◽  
Vol 57 (21) ◽  
pp. 5768-5771 ◽  
Author(s):  
Daniel A. Singleton ◽  
Jose P. Martinez ◽  
Grace M. Ndip
Keyword(s):  
Diels Alder ◽  
One Pot ◽  
In Situ Formation
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