A Hydrogen-Bonding-Modulated Molecular Rotor:  Environmental Effect in the Conformational Stability of Peptidomimetic Macrocyclic Cyclophanes

2006 ◽  
Vol 71 (6) ◽  
pp. 2242-2250 ◽  
Author(s):  
Ignacio Alfonso ◽  
M. Isabel Burguete ◽  
Santiago V. Luis
Keyword(s):  
Hydrogen Bonding ◽  
Environmental Effect ◽  
Conformational Stability ◽  
Molecular Rotor

Contribution of hydrogen bonding to the conformational stability of ribonuclease T1

Biochemistry ◽  
1992 ◽  
Vol 31 (3) ◽  
pp. 725-732 ◽  
Author(s):  
Bret A. Shirley ◽  
Patrick Stanssens ◽  
Ulrich Hahn ◽  
C. Nick Pace
Keyword(s):  
Hydrogen Bonding ◽  
Conformational Stability ◽  
Ribonuclease T1

scholarly journals Intramolecular hydrogen bonding and conformational preferences on 2-fluoro-phenylaminocyclohexanol

2018 ◽  
Author(s):  
Cassia Chiari ◽  
Claudio Francisco Tormena ◽  
Kahlil Schwanka Salome ◽  
Laiza Bruzadelle Loureiro ◽  
Renan Vidal Viesser
Keyword(s):  
Hydrogen Bonding ◽  
Driving Force ◽  
Conformational Stability ◽  
Intramolecular Hydrogen Bonding ◽  
Quantum Mechanical ◽  
Resonance Spectroscopy ◽  
Quantum Mechanical Calculations ◽  
Conformational Preferences ◽  
Intramolecular Hydrogen ◽  
Theoretical Results

The aim of this study is to evaluate the influence and strength of possible intramolecular hydrogen bonding (IntraHB) involving N-H--O, O-H--N, O-H--F and N-H--F molecular moieties as a driving force on the conformational preferences of 2-fluoro-phenylaminocyclohexanol. To achieve our purpose we synthesized the compound and performed it's characterization using Nuclear Magnetic Resonance Spectroscopy (NMR). Quantum mechanical calculations were carried out to evaluate the effect of IntraHB on the conformational stability. Experimental and theoretical results showed that N-H--F and O-H--N IntraHB have a greater influence on the conformacional preferably adopted by the molecule.

Guest control of a hydrogen bond-catalysed molecular rotor

2017 ◽  
Vol 53 (92) ◽  
pp. 12469-12472 ◽  
Author(s):  
Gregory T. Rushton ◽  
Erik C. Vik ◽  
William G. Burns ◽  
Roger D. Rasberry ◽  
Ken D. Shimizu
Keyword(s):  
Hydrogen Bond ◽  
Hydrogen Bonding ◽  
Intramolecular Hydrogen Bond ◽  
Molecular Rotor ◽  
Intramolecular Hydrogen

A molecular rotor is slowed by a hydrogen bonding guest that disrupts an intramolecular hydrogen bond, thus accelerating the rate of rotation.

Modulating the Rotation of a Molecular Rotor through Hydrogen-Bonding Interactions between the Rotator and Stator

2013 ◽  
Vol 52 (48) ◽  
pp. 12602-12605 ◽  
Author(s):  
Qian-Chong Zhang ◽  
Fang-Ting Wu ◽  
Hui-Min Hao ◽  
Hang Xu ◽  
Hai-Xia Zhao ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Molecular Rotor ◽  
Hydrogen Bonding Interactions

Influence of Hydrogen Bonding Interactions on the Conformation of Ribbon-like Zn(II) Complexes Bridged by Molybdates

2008 ◽  
Vol 63 (11) ◽  
pp. 1262-1266
Author(s):  
Tianhui Hua ◽  
Wansheng You ◽  
Limei Daia ◽  
Yi Zhao ◽  
Yong Fang ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonding ◽  
Conformational Stability ◽  
Water Molecules ◽  
Crystal Water ◽  
One Dimensional ◽  
Conformational Isomers ◽  
Hydrogen Bonding Interactions ◽  
3D Architecture ◽  
2D Network

Abstract The complexes [Zn(dpa)MoO4] (1) and [Zn(dpa)MoO4]·0.5H2O (20.5H2O) (dpa = 2,2'-dipyrid- ylamine) were synthesized hydrothermally. Single crystal structure analyses indicate that 1 and 2 are conformational isomers. They both consist of binuclear units of edge-sharing {ZnN2O3} trigonal bipyramids bridged by pairs of bidentate briding {MoO4}2- anions into a one-dimensional ribbon, but their orientations of the terminal O atoms of the {MoO4}2- anions are different. In 1 and 2, the ribbon-like chains are connected into a 2D network via hydrogen bonding interactions between the central N-H portions of the dpa molecules and the terminal O atoms of {MoO4} tetrahedra. For 2, in addition, the hydrogen bonding interactions between the crystal water molecules and the terminal O atoms of {MoO4} tetrahedra join the 2D layers into a 3D architecture. They play an important role not only in constructing the 3D architecture, but also in the conformational stability.

Sign in / Sign up

Export Citation Format

Share Document