Stereoselective Synthesis of Constrained Oxacyclic Hydroxyethylene Isosteres of Aspartic Protease Inhibitors:  Aldol and Mukaiyama Aldol Methodologies for Branched Tetrahydrofuran 2-Carboxylic Acids

2005 ◽  
Vol 70 (17) ◽  
pp. 6735-6745 ◽  
Author(s):  
Stephen Hanessian ◽  
Yihua Hou ◽  
Malken Bayrakdarian ◽  
Marina Tintelnot-Blomley
Keyword(s):  
Protease Inhibitors ◽  
Carboxylic Acids ◽  
Stereoselective Synthesis ◽  
Aspartic Protease ◽  
Mukaiyama Aldol

ChemInform Abstract: Potent HIV-1 Protease Inhibitors: Stereoselective Synthesis of a Dipeptide Mimic.

ChemInform ◽  
2010 ◽  
Vol 24 (22) ◽  
pp. no-no
Author(s):  
A. K. GHOSH ◽  
S. P. MCKEE ◽  
W. J. THOMPSON ◽  
P. L. DARKE ◽  
J. C. ZUGAY
Keyword(s):  
Protease Inhibitors ◽  
Stereoselective Synthesis ◽  
Hiv 1

Synthesis ofexo-3-Amino-7-azabicyclo[2.2.1]heptanes as a Class of Malarial Aspartic Protease Inhibitors: Exploration of Two Binding Pockets

2009 ◽  
Vol 2009 (11) ◽  
pp. 1707-1719 ◽  
Author(s):  
Martina Zürcher ◽  
Fraser Hof ◽  
Luzi Barandun ◽  
Andri Schütz ◽  
W. Bernd Schweizer ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Aspartic Protease ◽  
Binding Pockets

Stereoselective synthesis of erythro-β-hydroxy carboxylic acids via iron acyl complexes

1984 ◽  
Vol 25 (25) ◽  
pp. 2709-2712 ◽  
Author(s):  
Stephen G. Davies ◽  
Isabelle M. Dordor ◽  
Jonathan C. Walker ◽  
Peter Warner
Keyword(s):  
Carboxylic Acids ◽  
Stereoselective Synthesis ◽  
Acyl Complexes ◽  
Hydroxy Carboxylic Acids

Stereoselective Synthesis of 3-Aminoindan-1-ones and Subsequent Incorporation into HIV-1 Protease Inhibitors

2006 ◽  
Vol 71 (3) ◽  
pp. 1265-1268 ◽  
Author(s):  
Anna Arefalk ◽  
Johan Wannberg ◽  
Mats Larhed ◽  
Anders Hallberg
Keyword(s):  
Protease Inhibitors ◽  
Stereoselective Synthesis ◽  
Hiv 1 ◽  
Subsequent Incorporation
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