Synthesis ofexo-3-Amino-7-azabicyclo[2.2.1]heptanes as a Class of Malarial Aspartic Protease Inhibitors: Exploration of Two Binding Pockets

2009 ◽  
Vol 2009 (11) ◽  
pp. 1707-1719 ◽  
Author(s):  
Martina Zürcher ◽  
Fraser Hof ◽  
Luzi Barandun ◽  
Andri Schütz ◽  
W. Bernd Schweizer ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Aspartic Protease ◽  
Binding Pockets

Aspartic Protease Inhibitors Designed from Computer-Generated Templates Bind As Predicted

2001 ◽  
Vol 3 (15) ◽  
pp. 2309-2312 ◽  
Author(s):  
Amy S Ripka ◽  
Kenneth A. Satyshur ◽  
Regine S. Bohacek ◽  
Daniel H. Rich
Keyword(s):  
Protease Inhibitors ◽  
Aspartic Protease

Identification of acridinyl hydrazides as potent aspartic protease inhibitors

2008 ◽  
Vol 18 (9) ◽  
pp. 3011-3015 ◽  
Author(s):  
M. Kamran Azim ◽  
Waseem Ahmed ◽  
Ishtiaq A. Khan ◽  
Nosheen A. Rao ◽  
Khalid M. Khan
Keyword(s):  
Protease Inhibitors ◽  
Aspartic Protease

Design and Synthesis of Novel [60]Fullerene Derivatives as Potential HIV Aspartic Protease Inhibitors

2000 ◽  
Vol 2 (25) ◽  
pp. 3955-3958 ◽  
Author(s):  
Gian Luca Marcorin ◽  
Tatiana Da Ros ◽  
Sabrina Castellano ◽  
Giorgio Stefancich ◽  
Irena Bonin ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Aspartic Protease ◽  
Fullerene Derivatives ◽  
Design And Synthesis

Characterisation of hydrazides and hydrazine derivatives as novel aspartic protease inhibitors

2010 ◽  
Vol 25 (5) ◽  
pp. 673-678 ◽  
Author(s):  
Waseem Ahmed ◽  
Mubeen Rani ◽  
Ishtiaq A. Khan ◽  
Asif Iqbal ◽  
Khalid M. Khan ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Aspartic Protease ◽  
Hydrazine Derivatives

scholarly journals Design of Potent Aspartic Protease Inhibitors to Treat Various Diseases

2008 ◽  
Vol 341 (9) ◽  
pp. 523-535 ◽  
Author(s):  
Jeffrey-Tri Nguyen ◽  
Yoshio Hamada ◽  
Tooru Kimura ◽  
Yoshiaki Kiso
Keyword(s):  
Protease Inhibitors ◽  
Aspartic Protease

Unusual Bond Formation in Aspartic Protease Inhibitors: A Theoretical Study

2007 ◽  
Vol 13 (19) ◽  
pp. 5388-5393 ◽  
Author(s):  
Julien Pilmé ◽  
Hélène Berthoumieux ◽  
Vincent Robert ◽  
Paul Fleurat-Lessard
Keyword(s):  
Protease Inhibitors ◽  
Theoretical Study ◽  
Bond Formation ◽  
Aspartic Protease
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