Design, Synthesis, and Evaluation of 9-d-Ribitylamino-1,3,7,9-tetrahydro-2,6,8-purinetriones Bearing Alkyl Phosphate and α,α-Difluorophosphonate Substituents as Inhibitors of Riboflavin Synthase and Lumazine Synthase

2004 ◽  
Vol 69 (3) ◽  
pp. 601-612 ◽  
Author(s):  
Mark Cushman ◽  
Thota Sambaiah ◽  
Guangyi Jin ◽  
Boris Illarionov ◽  
Markus Fischer ◽  
...  
Keyword(s):  
Design Synthesis ◽  
Lumazine Synthase ◽  
Alkyl Phosphate

Design, Synthesis, and Evaluation of 6-Carboxyalkyl and 6-Phosphonoxyalkyl Derivatives of 7-Oxo-8-ribitylaminolumazines as Inhibitors of Riboflavin Synthase and Lumazine Synthase

2002 ◽  
Vol 67 (16) ◽  
pp. 5807-5816 ◽  
Author(s):  
Mark Cushman ◽  
Donglai Yang ◽  
Stefan Gerhardt ◽  
Robert Huber ◽  
Markus Fischer ◽  
...  
Keyword(s):  
Design Synthesis ◽  
Lumazine Synthase ◽  
Derivatives Of
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