A New Synthesis of N.alpha.,N.delta.-Protected N.delta.-Hydroxycycloornithine and Its Homolog from an L-Glutamic Acid Derivative

1994 ◽  
Vol 59 (4) ◽  
pp. 929-931 ◽  
Author(s):  
Takeshi Sakamoto ◽  
Yasuo Kikugawa
Keyword(s):  
Glutamic Acid ◽  
Acid Derivative ◽  
New Synthesis

Improved Cleanup and Derivatization for Gas Chromatographic Determination of Monosodium Glutamate in Foods

1983 ◽  
Vol 66 (6) ◽  
pp. 1528-1531 ◽  
Author(s):  
Hiroshi Nakanishi
Keyword(s):  
Glutamic Acid ◽  
Acid Derivative ◽  
Monosodium Glutamate ◽  
Chromatographic Determination ◽  
Flame Ionization Detection ◽  
Gas Chromatograph ◽  
Flame Ionization ◽  
Acetone Water ◽  
Chromatographic Procedure

Abstract A gas chromatographic procedure is described for determining monosodium glutamate (MSG) in several types of food. A sample is extracted with acetone- water (1 + 1). Acetone is evaporated and an aliquot of the extract is buffered with 1M NH4OH-1M NH4CI pH 9 solution, and chromatographed directly on a column of QAE Sephadex A-25 that has been pretreated with the same buffer. MSG is eluted with 0.1N HC1, and a portion of the eluate is evaporated to dryness and reacted with dimethylformamide( DMF)-dimethylacetal to form the glutamic acid derivative, which is injected into a gas chromatograph and measured by flame ionization detection. Recoveries of MSG from sample fortified at 5-500 mg ranged from 92.8 to 100%.

scholarly journals A NEW SYNTHESIS OF GLUTAMIC ACID

1931 ◽  
Vol 94 (2) ◽  
pp. 599-609
Author(s):  
Max S. Dunn ◽  
B.W. Smart ◽  
C.E. Redemann ◽  
K.E. Brown
Keyword(s):  
Glutamic Acid ◽  
New Synthesis

A novel method of conjugation of daunomycin with antibody with a poly(L-glutamic acid) derivative as intermediate drug carrier. An anti-.alpha.-fetoprotein antibody-daunomycin conjugate

1984 ◽  
Vol 27 (12) ◽  
pp. 1602-1607 ◽  
Author(s):  
Yoshinori Kato ◽  
Naoji Umemoto ◽  
Yasutaka Kayama ◽  
Hisashi Fukushima ◽  
Yumiko Takeda ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Acid Derivative ◽  
Drug Carrier ◽  
Alpha Fetoprotein ◽  
Novel Method

Pharmacokinetic Properties of a New Glutamic Acid Derivative Glutaron

2015 ◽  
Vol 159 (2) ◽  
pp. 229-231 ◽  
Author(s):  
L. A. Smirnova ◽  
A. F. Ryabukha ◽  
K. A. Kuznetsov ◽  
E. A. Suchkov ◽  
V. N. Perfilova ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Acid Derivative ◽  
Pharmacokinetic Properties

New synthesis of N-[4-[[(2-amino-4(3H)-oxopyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamic acid (8-deazafolic acid) and the preparation of some 5,6,7,8-tetrahydro derivatives

1981 ◽  
Vol 24 (10) ◽  
pp. 1254-1258 ◽  
Author(s):  
Carroll Temple ◽  
C. L. Kussner ◽  
J. D. Rose ◽  
D. L. Smithers ◽  
L. L. Bennett ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
New Synthesis

A CONVENIENT SYNTHESIS OF DL-GLUTAMIC ACID FROM β-PROPIOLACTONE

1956 ◽  
Vol 34 (10) ◽  
pp. 1440-1443 ◽  
Author(s):  
Guy Talbot ◽  
Roger Gaudry ◽  
Louis Berlinguet
Keyword(s):  
Glutamic Acid ◽  
Acid Hydrolysis ◽  
Sodium Salt ◽  
Intermediate Product ◽  
Diethyl Ester ◽  
New Synthesis ◽  
Convenient Synthesis

A new synthesis of DL-glutamic acid was carried out in an over-all yield of 87% from condensation between β-propiolactone and the sodium salt of diethyl acetamidomalonate, followed by acid hydrolysis. When desired, the intermediate product, the diethyl ester of N-acetyl-2-carbethoxyglutamic acid, could be isolated in a 68% yield and hydrolyzed to glutamic acid via the hydrochloride in a 95% yield.

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