Chiral Synthesis via Organoboranes. 39. A Facile Synthesis of .gamma.-Substituted-.gamma.-butyrolactones in Exceptionally High Enantiomeric Purity

Herbert C. Brown; Shekhar V. Kulkarni; Uday S. Racherla

doi:10.1021/jo00081a014

Chiral Synthesis via Organoboranes. 39. A Facile Synthesis of .gamma.-Substituted-.gamma.-butyrolactones in Exceptionally High Enantiomeric Purity

The Journal of Organic Chemistry ◽

10.1021/jo00081a014 ◽

1994 ◽

Vol 59 (2) ◽

pp. 365-369 ◽

Cited By ~ 84

Author(s):

Herbert C. Brown ◽

Shekhar V. Kulkarni ◽

Uday S. Racherla

Keyword(s):

Enantiomeric Purity ◽

Facile Synthesis ◽

Chiral Synthesis

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Chiral synthesis via organoboranes. 30. Facile synthesis, by the Matteson asymmetric homologation procedure, of .alpha.-methyl boronic acids not available from asymmetric hydroboration and their conversion into the corresponding aldehydes, ketones, carboxylic acids, and amines of high enantiomeric purity

The Journal of Organic Chemistry ◽

10.1021/jo00010a022 ◽

1991 ◽

Vol 56 (10) ◽

pp. 3286-3294 ◽

Cited By ~ 61

Author(s):

Milind V. Rangaishenvi ◽

Bakthan Singaram ◽

Herbert C. Brown

Keyword(s):

Carboxylic Acids ◽

Boronic Acids ◽

Enantiomeric Purity ◽

Facile Synthesis ◽

Chiral Synthesis ◽

Asymmetric Hydroboration

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ChemInform Abstract: Chiral Synthesis via Organoboranes. Part 39. A Facile Synthesis of . gamma.-Substituted-γ-butyrolactones in Exceptionally High Enantiomeric Purity.

ChemInform ◽

10.1002/chin.199423130 ◽

2010 ◽

Vol 25 (23) ◽

pp. no-no

Author(s):

H. C. BROWN ◽

S. V. KULKARNI ◽

U. S. RACHERLA

Keyword(s):

Enantiomeric Purity ◽

Facile Synthesis ◽

Chiral Synthesis

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ChemInform Abstract: Chiral Synthesis via Organoboranes. Part 18. Selective Reductions. Part 43. Diisopinocampheylchloroborane as an Excellent Chiral Reducing Reagent for the Synthesis of Halo Alcohols of High Enantiomeric Purity. A Highly Enantioselectiv

ChemInform ◽

10.1002/chin.198848103 ◽

1988 ◽

Vol 19 (48) ◽

Author(s):

M. SREBNIK ◽

P. V. RAMACHANDRAN ◽

H. C. BROWN

Keyword(s):

Enantiomeric Purity ◽

Chiral Synthesis

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Chiral synthesis via organoboranes. 18. Selective reductions. 43. Diisopinocampheylchloroborane as an excellent chiral reducing reagent for the synthesis of halo alcohols of high enantiomeric purity. A highly enantioselective synthesis of both optical isomers of Tomoxetine, Fluoxetine, and Nisoxetine

The Journal of Organic Chemistry ◽

10.1021/jo00248a005 ◽

1988 ◽

Vol 53 (13) ◽

pp. 2916-2920 ◽

Cited By ~ 92

Author(s):

Morris Srebnik ◽

P. V. Ramachandran ◽

Herbert C. Brown

Keyword(s):

Enantiomeric Purity ◽

Enantioselective Synthesis ◽

Optical Isomers ◽

Chiral Synthesis

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A facile synthesis of statine and analogs by reduction of .beta.-keto esters derived from Boc-protected amino acids. HPLC analyses of their enantiomeric purity

The Journal of Organic Chemistry ◽

10.1021/jo00239a035 ◽

1988 ◽

Vol 53 (4) ◽

pp. 869-873 ◽

Cited By ~ 58

Author(s):

Juergen Maibaum ◽

Daniel H. Rich

Keyword(s):

Amino Acids ◽

Enantiomeric Purity ◽

Facile Synthesis ◽

Keto Esters ◽

Hplc Analyses

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ChemInform Abstract: A Facile Synthesis of Statine and Analogues by Reduction of β-Keto Esters Derived from Boc-Protected Amino Acids. HPLC Analyses of Their Enantiomeric Purity.

ChemInform ◽

10.1002/chin.198829301 ◽

1988 ◽

Vol 19 (29) ◽

Author(s):

J. MAIBAUM ◽

D. H. RICH

Keyword(s):

Amino Acids ◽

Enantiomeric Purity ◽

Facile Synthesis ◽

Keto Esters ◽

Hplc Analyses

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Chiral Synthesis via Organoboranes. 11. Hydroboration. 82. Asymmetric Hydroboration of 1-Heteroarylcycloalkenes with Monoisopinocampheylborane. Synthesis oftrans-2-Heteroarylcycloalkyl Boronates and Derived Alcohols of Very High Enantiomeric Purity

Bulletin of the Chemical Society of Japan ◽

10.1246/bcsj.61.93 ◽

1988 ◽

Vol 61 (1) ◽

pp. 93-100 ◽

Cited By ~ 18

Author(s):

Herbert C. Brown ◽

Ashok K. Gupta ◽

J. V. N. Vara Prasad

Keyword(s):

Enantiomeric Purity ◽

Chiral Synthesis ◽

Asymmetric Hydroboration ◽

Very High

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Chiral synthesis via organoboranes. 6. Hydroboration. 74. Asymmetric hydroboration of representative heterocyclic olefins with diisopinocampheylborane. Synthesis of heterocyclic boronates and heterocyclic alcohols of very high enantiomeric purity

Journal of the American Chemical Society ◽

10.1021/ja00268a053 ◽

1986 ◽

Vol 108 (8) ◽

pp. 2049-2054 ◽

Cited By ~ 77

Author(s):

Herbert C. Brown ◽

J. V. N. Vara. Prasad

Keyword(s):

Enantiomeric Purity ◽

Chiral Synthesis ◽

Asymmetric Hydroboration ◽

Very High

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ChemInform Abstract: Chiral Synthesis via Organoboranes. Part 32. Synthesis of B-(Cycloalk- 2-enyl)diisopinocampheylboranes of High Enantiomeric Purity via the Asymmetric Hydroboration of Cycloalka-1,3-dienes. Successful Asymmetric Allylborations of Aldeh

ChemInform ◽

10.1002/chin.199206071 ◽

2010 ◽

Vol 23 (6) ◽

pp. no-no

Author(s):

H. C. BROWN ◽

K. S. BHAT ◽

P. K. JADHAV

Keyword(s):

Enantiomeric Purity ◽

Chiral Synthesis ◽

Asymmetric Hydroboration

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ChemInform Abstract: Stereoselective Construction of Quaternary Carbon Centers via Reaction of Heterocuprates with Chiral Allenic Bromides: A Facile Synthesis of Butylethylmethylpropylmethane in High Enantiomeric Purity.

ChemInform ◽

10.1002/chin.198923109 ◽

1989 ◽

Vol 20 (23) ◽

Author(s):

A. M. CAPORUSSO ◽

C. CONSOLONI ◽

L. LARDICCI

Keyword(s):

Enantiomeric Purity ◽

Quaternary Carbon ◽

Facile Synthesis ◽

Carbon Centers

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