Structure−Activity Relationships:  Analogues of the Dicaffeoylquinic and Dicaffeoyltartaric Acids as Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and Replication†

Peter J. King; Guoxiang Ma; Wenfang Miao; Qi Jia; Brenda R. McDougall; Manfred G. Reinecke; Chris Cornell; Jean Kuan; Tracey R. Kim; W. Edward Robinson

doi:10.1021/jm9804735

Structure−Activity Relationships: Analogues of the Dicaffeoylquinic and Dicaffeoyltartaric Acids as Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and Replication†

Journal of Medicinal Chemistry ◽

10.1021/jm9804735 ◽

1999 ◽

Vol 42 (3) ◽

pp. 497-509 ◽

Cited By ~ 116

Author(s):

Peter J. King ◽

Guoxiang Ma ◽

Wenfang Miao ◽

Qi Jia ◽

Brenda R. McDougall ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

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Structure-activity relationships of fluorinated nucleoside analogs and their synergistic effect in combination with phosphonoformate against human immunodeficiency virus type 1.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.33.12.2083 ◽

1989 ◽

Vol 33 (12) ◽

pp. 2083-2088 ◽

Cited By ~ 42

Author(s):

R Koshida ◽

S Cox ◽

J Harmenberg ◽

G Gilljam ◽

B Wahren

Keyword(s):

Human Immunodeficiency Virus ◽

Synergistic Effect ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Analogs ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

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Structure-activity relationships of polybiguanides with activity against human immunodeficiency virus type 1

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2010.10.001 ◽

2010 ◽

Vol 64 (10) ◽

pp. 723-732 ◽

Cited By ~ 13

Author(s):

Shendra R. Passic ◽

Mary Lee Ferguson ◽

Bradley J. Catalone ◽

Tina Kish-Catalone ◽

Vladyslav Kholodovych ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

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Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 12. Structure–Activity Relationships Associated with 4-Fluoro-6-azaindole Derivatives Leading to the Identification of 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248)

Journal of Medicinal Chemistry ◽

10.1021/jm3016377 ◽

2013 ◽

Vol 56 (4) ◽

pp. 1656-1669 ◽

Cited By ~ 37

Author(s):

Alicia Regueiro-Ren ◽

Qiufen M. Xue ◽

Jacob J. Swidorski ◽

Yi-Fei Gong ◽

Marina Mathew ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Hiv 1

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Structure-activity relationships and mode of action of 5-mercapto-substituted oligo- and polynucleotides as antitemplates inhibiting replication of human immunodeficiency virus type 1.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.36.1.108 ◽

1992 ◽

Vol 36 (1) ◽

pp. 108-114 ◽

Cited By ~ 11

Author(s):

T J Bardos ◽

R F Schinazi ◽

K H Ling ◽

A R Heider

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Mode Of Action ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

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Structure-activity relationship studies for various oxathiin carboxanilide derivatives modified in the oxathiin moiety against wild-type and mutant human immunodeficiency virus type 1 strains

Antiviral Research ◽

10.1016/0166-3542(95)94763-r ◽

1995 ◽

Vol 26 (3) ◽

pp. A261

Author(s):

J. Balzarini ◽

W.G. Brouwer ◽

D.C. Dao ◽

E.E. Felauer ◽

W.A. Harrison ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Wild Type ◽

Structure Activity ◽

Immunodeficiency Virus

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ChemInform Abstract: Preparation and Structure-Activity Relationship of Novel P1/P1′- Substituted Cyclic Urea-Based Human Immunodeficiency Virus Type-1 Protease Inhibitors.

ChemInform ◽

10.1002/chin.199637224 ◽

2010 ◽

Vol 27 (37) ◽

pp. no-no

Author(s):

D. A. NUGIEL ◽

K. JACOBS ◽

T. WORLEY ◽

M. PATEL ◽

R. F. III KALTENBACH ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Protease Inhibitors ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Relationship Of

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Structure–activity relationship studies of 1-(4-chloro-2,5-dimethoxyphenyl)-3-(3-propoxypropyl)thiourea, a non-nucleoside reverse transcriptase inhibitor of human immunodeficiency virus type-1

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2010.11.003 ◽

2011 ◽

Vol 46 (2) ◽

pp. 447-467 ◽

Cited By ~ 4

Author(s):

Michal Weitman ◽

Keti Lerman ◽

Abraham Nudelman ◽

Dan Thomas Major ◽

Amnon Hizi ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Reverse Transcriptase Inhibitor ◽

Transcriptase Inhibitor ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Reverse Transcriptase Inhibitor

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Studies of Human Immunodeficiency Virus Type 1 (HIV-1) Protease Inhibitors. III. Structure-Activity Relationship of HIV-1 Protease Inhibitors Containing Cyclohexylalanylalanine Hydroxyethylene Dipeptide lsostere.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.42.534 ◽

1994 ◽

Vol 42 (3) ◽

pp. 534-540 ◽

Cited By ~ 5

Author(s):

Mitsuya SAKURAI ◽

Susumu HIGASHIDA ◽

Machiko SUGANO ◽

Hiroshi HANDA ◽

Tomoaki KOMAI ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Protease Inhibitors ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Activity Relationship ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Relationship Of ◽

Hiv 1

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Inhibitors of Human Immunodeficiency Virus Type 1 Derived from gp41 Transmembrane Protein: Structure−Activity Studies

Journal of Medicinal Chemistry ◽

10.1021/jm950709u ◽

1996 ◽

Vol 39 (14) ◽

pp. 2681-2689 ◽

Cited By ~ 8

Author(s):

Wieslaw M. Kazmierski ◽

Richard J. Hazen ◽

Ann Aulabaugh ◽

Marty H. StClair

Keyword(s):

Human Immunodeficiency Virus ◽

Protein Structure ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Transmembrane Protein ◽

Structure Activity ◽

Immunodeficiency Virus

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Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 1. Synthesis and Structure−Activity Relationship of a Class of Human Immunodeficiency Virus type 1 Integrase Inhibitors†

Journal of Medicinal Chemistry ◽

10.1021/jm8003784 ◽

2008 ◽

Vol 51 (16) ◽

pp. 5125-5129 ◽

Cited By ~ 109

Author(s):

Serena Pasquini ◽

Claudia Mugnaini ◽

Cristina Tintori ◽

Maurizio Botta ◽

Alejandro Trejos ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Carboxylic Acid ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Activity Relationship ◽

Integrase Inhibitors ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Relationship Of

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