Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 12. Structure–Activity Relationships Associated with 4-Fluoro-6-azaindole Derivatives Leading to the Identification of 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248)

Alicia Regueiro-Ren; Qiufen M. Xue; Jacob J. Swidorski; Yi-Fei Gong; Marina Mathew; Dawn D. Parker; Zheng Yang; Betsy Eggers; Celia D’Arienzo; Yongnian Sun; Jacek Malinowski; Qi Gao; Dedong Wu; David R. Langley; Richard J. Colonno; Caly Chien; Dennis M. Grasela; Ming Zheng; Pin-Fang Lin; Nicholas A. Meanwell; John F. Kadow

doi:10.1021/jm3016377

Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Attachment. 12. Structure–Activity Relationships Associated with 4-Fluoro-6-azaindole Derivatives Leading to the Identification of 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248)

Journal of Medicinal Chemistry ◽

10.1021/jm3016377 ◽

2013 ◽

Vol 56 (4) ◽

pp. 1656-1669 ◽

Cited By ~ 37

Author(s):

Alicia Regueiro-Ren ◽

Qiufen M. Xue ◽

Jacob J. Swidorski ◽

Yi-Fei Gong ◽

Marina Mathew ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Hiv 1

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Structure-activity relationships of fluorinated nucleoside analogs and their synergistic effect in combination with phosphonoformate against human immunodeficiency virus type 1.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.33.12.2083 ◽

1989 ◽

Vol 33 (12) ◽

pp. 2083-2088 ◽

Cited By ~ 42

Author(s):

R Koshida ◽

S Cox ◽

J Harmenberg ◽

G Gilljam ◽

B Wahren

Keyword(s):

Human Immunodeficiency Virus ◽

Synergistic Effect ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Nucleoside Analogs ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

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Structure-activity relationships of polybiguanides with activity against human immunodeficiency virus type 1

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2010.10.001 ◽

2010 ◽

Vol 64 (10) ◽

pp. 723-732 ◽

Cited By ~ 13

Author(s):

Shendra R. Passic ◽

Mary Lee Ferguson ◽

Bradley J. Catalone ◽

Tina Kish-Catalone ◽

Vladyslav Kholodovych ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

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Studies of Human Immunodeficiency Virus Type 1 (HIV-1) Protease Inhibitors. III. Structure-Activity Relationship of HIV-1 Protease Inhibitors Containing Cyclohexylalanylalanine Hydroxyethylene Dipeptide lsostere.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.42.534 ◽

1994 ◽

Vol 42 (3) ◽

pp. 534-540 ◽

Cited By ~ 5

Author(s):

Mitsuya SAKURAI ◽

Susumu HIGASHIDA ◽

Machiko SUGANO ◽

Hiroshi HANDA ◽

Tomoaki KOMAI ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Protease Inhibitors ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Activity Relationship ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Relationship Of ◽

Hiv 1

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Structure−Activity Relationships: Analogues of the Dicaffeoylquinic and Dicaffeoyltartaric Acids as Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and Replication†

Journal of Medicinal Chemistry ◽

10.1021/jm9804735 ◽

1999 ◽

Vol 42 (3) ◽

pp. 497-509 ◽

Cited By ~ 116

Author(s):

Peter J. King ◽

Guoxiang Ma ◽

Wenfang Miao ◽

Qi Jia ◽

Brenda R. McDougall ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

Download Full-text

Structure-activity relationships and mode of action of 5-mercapto-substituted oligo- and polynucleotides as antitemplates inhibiting replication of human immunodeficiency virus type 1.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.36.1.108 ◽

1992 ◽

Vol 36 (1) ◽

pp. 108-114 ◽

Cited By ~ 11

Author(s):

T J Bardos ◽

R F Schinazi ◽

K H Ling ◽

A R Heider

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Mode Of Action ◽

Structure Activity Relationships ◽

Structure Activity ◽

Immunodeficiency Virus

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Human Immunodeficiency Virus Type 1 Pharmacogenomics in Clinical Practice: Relevance of HIV-1 Drug Resistance Testing (Part 2)

Journal of Environmental Pathology Toxicology and Oncology ◽

10.1615/jenvpathtoxoncol.v22.i4.20 ◽

2003 ◽

Vol 22 (4) ◽

pp. 281-286 ◽

Cited By ~ 1

Author(s):

Martha S. Bianchi ◽

Alejandro D. Bolzan

Keyword(s):

Human Immunodeficiency Virus ◽

Drug Resistance ◽

Clinical Practice ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Resistance Testing ◽

Drug Resistance Testing ◽

Immunodeficiency Virus ◽

Hiv 1

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A Study to Assess Effectiveness and Safety of Fixed Dose Combination of Lopinavir/Ritonavir (LPV/r) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Patients After Switching From Kaletra in the Routine Clinical Settings of Russian Federation

Case Medical Research ◽

10.31525/ct1-nct04138199 ◽

2019 ◽

Author(s):

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Russian Federation ◽

Fixed Dose ◽

Clinical Settings ◽

Immunodeficiency Virus ◽

Dose Combination ◽

Hiv 1

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Faculty Opinions recommendation of Human Cytomegalovirus Enhances Placental Susceptibility and Replication of Human Immunodeficiency Virus Type 1 (HIV-1), Which May Facilitate In Utero HIV-1 Transmission.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733367277.793546910 ◽

2018 ◽

Author(s):

Sarah Rowland-Jones ◽

Michael Boswell

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Human Cytomegalovirus ◽

In Utero ◽

Immunodeficiency Virus ◽

Hiv 1

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Use of polimerase chain reaction for neonatal diagnosis of human immunodeficiency virus type 1 (HIV-1) perinatal infection

Jornal de Pediatria ◽

10.2223/jped.677 ◽

1994 ◽

Vol 70 (6) ◽

Author(s):

Marisa Márcia Mussi-Pinhata ◽

Maria Célia C. Ferez ◽

Dimas T. Covas ◽

Geraldo Duarte ◽

Márcia L. Isaac ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Perinatal Infection ◽

Chain Reaction ◽

Neonatal Diagnosis ◽

Immunodeficiency Virus ◽

Hiv 1

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Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1.

Journal of Virology ◽

10.1128/jvi.66.7.4464-4469.1992 ◽

1992 ◽

Vol 66 (7) ◽

pp. 4464-4469 ◽

Cited By ~ 49

Author(s):

P W Berman ◽

T J Matthews ◽

L Riddle ◽

M Champe ◽

M R Hobbs ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Human Immunodeficiency Virus Type ◽

Virus Type ◽

Clinical Isolates ◽

Immunodeficiency Virus ◽

Hiv 1

Download Full-text