Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease:  Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1Glutamine Isosteric Replacements

1998 ◽  
Vol 41 (15) ◽  
pp. 2786-2805 ◽  
Author(s):  
Stephen E. Webber ◽  
Koji Okano ◽  
Thomas L. Little ◽  
Siegfried H. Reich ◽  
Yue Xin ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Human Rhinovirus ◽  
Design Synthesis ◽  
3C Protease ◽  
Structure Solution ◽  
Cocrystal Structure

Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease:  Structure-Based Design, Synthesis, and Biological Evaluation

2000 ◽  
Vol 43 (9) ◽  
pp. 1670-1683 ◽  
Author(s):  
Siegfried H. Reich ◽  
Theodore Johnson ◽  
Michael B. Wallace ◽  
Susan E. Kephart ◽  
Shella A. Fuhrman ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Human Rhinovirus ◽  
Design Synthesis ◽  
3C Protease ◽  
Substituted Benzamide ◽  
Synthesis And Biological Evaluation
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