Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 6. Structure−Activity Studies of Orally Bioavailable, 2-Pyridone-Containing Peptidomimetics

2002 ◽  
Vol 45 (8) ◽  
pp. 1607-1623 ◽  
Author(s):  
Peter S. Dragovich ◽  
Thomas J. Prins ◽  
Ru Zhou ◽  
Edward L. Brown ◽  
Fausto C. Maldonado ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Biological Evaluation ◽  
Human Rhinovirus ◽  
Design Synthesis ◽  
3C Protease ◽  
Structure Activity ◽  
Orally Bioavailable ◽  
Synthesis And Biological Evaluation

Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease:  Structure-Based Design, Synthesis, and Biological Evaluation

2000 ◽  
Vol 43 (9) ◽  
pp. 1670-1683 ◽  
Author(s):  
Siegfried H. Reich ◽  
Theodore Johnson ◽  
Michael B. Wallace ◽  
Susan E. Kephart ◽  
Shella A. Fuhrman ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Human Rhinovirus ◽  
Design Synthesis ◽  
3C Protease ◽  
Substituted Benzamide ◽  
Synthesis And Biological Evaluation
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