Design, Synthesis, and Biological Evaluation of Phenylamino-Substituted 6,11-Dihydro-dibenzo[b,e]oxepin-11-ones and Dibenzo[a,d]cycloheptan-5-ones:  Novel p38 MAP Kinase Inhibitors

2006 ◽  
Vol 49 (26) ◽  
pp. 7912-7915 ◽  
Author(s):  
Stefan A. Laufer ◽  
Gabriele M. Ahrens ◽  
Solveigh C. Karcher ◽  
Jörg S. Hering ◽  
Raimund Niess
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

scholarly journals Design, Synthesis, and Biological Evaluation of Chromone-Based p38 MAP Kinase Inhibitors

2011 ◽  
Vol 54 (20) ◽  
pp. 7427-7431 ◽  
Author(s):  
Christine Dyrager ◽  
Linda Nilsson Möllers ◽  
Linda Karlsson Kjäll ◽  
John Patrick Alao ◽  
Peter Dinér ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

Structure‐Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5‐ b ]Pyridin‐2‐one‐Based p38 MAP Kinase Inhibitors: Part 2

ChemMedChem ◽  
2019 ◽  
Vol 14 (24) ◽  
pp. 2093-2101
Author(s):  
Akira Kaieda ◽  
Masashi Takahashi ◽  
Hiromi Fukuda ◽  
Rei Okamoto ◽  
Shinji Morimoto ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

Structure‐Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5‐ b ]pyridin‐2‐one‐Based p38 MAP Kinase Inhibitors: Part 1

ChemMedChem ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. 1022-1030 ◽  
Author(s):  
Akira Kaieda ◽  
Masashi Takahashi ◽  
Hiromi Fukuda ◽  
Rei Okamoto ◽  
Shinji Morimoto ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors

2018 ◽  
Vol 26 (3) ◽  
pp. 647-660 ◽  
Author(s):  
Akira Kaieda ◽  
Masashi Takahashi ◽  
Takafumi Takai ◽  
Masayuki Goto ◽  
Takahiro Miyazaki ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

2-Acylaminopyridin-4-ylimidazoles as p38 MAP Kinase Inhibitors: Design, Synthesis, and Biological and Metabolic Evaluations

ChemMedChem ◽  
2009 ◽  
Vol 4 (11) ◽  
pp. 1939-1948 ◽  
Author(s):  
Katharina Ziegler ◽  
Dominik R. J. Hauser ◽  
Anke Unger ◽  
Wolfgang Albrecht ◽  
Stefan A. Laufer
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors
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