Effects of chitosan hydrolyzates on lipid absorption and on serum and liver lipid concentration in rats

1993 ◽  
Vol 41 (3) ◽  
pp. 431-435 ◽  
Author(s):  
Ikuo. Ikeda ◽  
Michihiro. Sugano ◽  
Katsuko. Yoshida ◽  
Eiji. Sasaki ◽  
Yasushi. Iwamoto ◽  
...  
Keyword(s):  
Liver Lipid ◽  
Lipid Absorption ◽  
Lipid Concentration ◽  
Liver Lipid Concentration

scholarly journals Saturated fat-rich diet increases fetal lipids and modulates LPL and leptin receptor expression in rat placentas

2013 ◽  
Vol 217 (3) ◽  
pp. 303-315 ◽  
Author(s):  
M B Mazzucco ◽  
R Higa ◽  
E Capobianco ◽  
M Kurtz ◽  
A Jawerbaum ◽  
...  
Keyword(s):  
Leptin Receptor ◽  
Fetal Liver ◽  
Liver Lipid ◽  
Saturated Fat ◽  
Receptor Expression ◽  
Lipid Concentration ◽  
Old Rats ◽  
Liver Lipid Concentration ◽  
Leptin Expression ◽  
Layer Chromatography

Metabolic alterations in obese and overweight mothers impact the placenta and the fetus, leading to anomalies in fetal growth and lipid accretion. The primary aim of the study was to examine the effect of a saturated fat-rich diet (FD) on growth, lipid accretion, and lipases, leptin and leptin receptor (ObR) expression in the placenta and fetal liver. We also aimed to find a role for fetal leptin in the modulation of placental and fetal liver lipase and ObR expression. Six-week-old rats were fed with a standard rat chow (control) or a 25% FD for 7 weeks until mating and during pregnancy. Also, in a group of control rats, fetuses were injected with leptin on days 19, 20, and 21 of pregnancy. On day 21, we assessed lipidemia, insulinemia, and leptinemia in mothers and fetuses. In the placenta and fetal liver, lipid concentration was assessed by thin layer chromatography (TLC) and the gene expression of lipoprotein lipase (LPL), endothelial lipase, insulin receptor (Insr), leptin, and ObR by RT-PCR. The FD induced hypertriglyceridemia and hyperleptinemia (P<0.01) in mothers and fetuses, an increase in maternal (P<0.05) and fetal weight (P<0.01), overaccumulation of lipids in fetal liver (P<0.01), and enhanced leptin expression in the placenta and fetal liver (P<0.05). Placental expression of IR and LPL was increased (P<0.05), and ObR decreased (P<0.05) in the FD group. Fetal administration of leptin induced the placental and fetal liver downregulation of ObR (P<0.05) and upregulation of LPL expression (P<0.05). The FD led to increased fetal lipid levels, which may result from high maternal lipid availability and fetal leptin effects.

scholarly journals The influence of essential fatty acids and food restriction on the specific activities of hepatic lipogenic and glutamate-metabolizing enzymes in the laying hen

1975 ◽  
Vol 33 (3) ◽  
pp. 439-445 ◽  
Author(s):  
D. Balnave
Keyword(s):  
Essential Fatty Acids ◽  
Liver Lipid ◽  
Feeding Time ◽  
Lipid Concentration ◽  
Deficient Diet ◽  
Liver Size ◽  
Metabolizing Enzymes ◽  
Daily Food ◽  
Specific Activities ◽  
Liver Lipid Concentration

1. Extended feeding of an essential fatty acid (EFA)-deficient diet to laying hens increased liver size and liver lipid concentration.2. The specific activities of hepatic lipogenic and glutamate-metabolizing enzymes were increased by feeding the EFA-deficient diet.3. Restriction of daily food intake to 75 % of ad lib. intake did not affect the response to dietary fat concentration.4. Hepatic enzyme activities in hens fed on restricted amounts of food and killed just before, or after, the normal daily feeding time indicated no reduced capacity for lipogenesis at the earlier time.

scholarly journals A study of the effects of dietary added cupric oxide on the laying, domestic fowl and a comparison with the effects of hydrated copper sulphate

1981 ◽  
Vol 45 (1) ◽  
pp. 99-110 ◽  
Author(s):  
N. Jackson ◽  
Mary H. Stevenson
Keyword(s):  
Body Weight ◽  
Food Intake ◽  
Egg Production ◽  
Cupric Oxide ◽  
Liver Lipid ◽  
Food Conversion ◽  
Lipid Concentration ◽  
Unit Body Weight ◽  
Quadratic Response ◽  
Liver Lipid Concentration

1. An experiment is reported in which copper, as cupric oxide, was fed to two breeds of laying hen for 336 d at levels equivalent to 150, 300, 450, 600 and 750 mg added Cu/kg diet. The results obtained were compared with those found using similar diets to which the Cu was added as CuSO4. 5H2O.2. Addition of the CuO had no effect on food intake, food conversion efficiency, body-weight or egg production. The CuSO4 addition caused the quadratic response of food intake and the adverse effects on food intake, egg production and body-weight noted in previous experiments.3. The CuO had no effect on liver, kidney, ovary, oviduct or gizzard weight per unit body-weight while the CuSO4 decreased these with the exception of gizzard weight which was significantly increased.4. CuO addition did not affect liver Cu concentration but CuSO4 caused a subtantial increase of liver Cu especially at the 750 mg Cu/kg level of addition.5. CuO addition had no effect on liver lipid concentration but this was depressed at the highest level of CuSO4 addition. Effects on individual fatty acids are presented but no specific conclusions have been reached.

scholarly journals Effect of Awamori Lees on Growth, Serum and Liver Lipid Concentration in Rats Fed a High Cholesterol Diet

2010 ◽  
Vol 57 (3) ◽  
pp. 93-99 ◽  
Author(s):  
Toshitsugu Nohara ◽  
Shuntoku Uechi ◽  
Goh Ogura ◽  
Kunioki Hayashi ◽  
Katsunori Sunagawa
Keyword(s):  
Liver Lipid ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
Lipid Concentration ◽  
Liver Lipid Concentration

Sexual dimorphism in an under-ice spawning fish: the burbot (Lota lota)

2013 ◽  
Vol 91 (10) ◽  
pp. 732-740 ◽  
Author(s):  
P.A. Cott ◽  
T.A. Johnston ◽  
J.M. Gunn
Keyword(s):  
Sexual Dimorphism ◽  
Visual Cues ◽  
Liver Lipid ◽  
Sexually Dimorphic ◽  
Lipid Concentration ◽  
Lota Lota ◽  
Selective Pressures ◽  
Liver Lipid Concentration ◽  
Boreal Fishes ◽  
Bladder Mass

Sexual dimorphic characteristics arise in response to differing selective pressures on the sexes and can be used to attract mates or signal reproductive readiness. How sexual dimorphism is expressed where visual cues may be of limited use is an underexplored aspect of reproductive ecology. The burbot (Lota lota (L., 1758)) is a common boreal fish that is not overtly sexually dimorphic. It spawns mid-winter in a light-limited under-ice environment. We examined a variety of morphological and reproductive characteristics in burbot from a northern lake over one full year to assess both seasonal and sex-based variation. Spawning occurred under ice in early February. Seasonal variation was more pronounced in females for many of the traits examined. Growth, fin lengths, swim bladder mass, and liver lipid concentration did not differ between the sexes. Male burbot had significantly higher body condition, larger gas glands, and smaller livers. Males also had significantly larger gonads than females, unusual for boreal fishes. The high gonadal investment of male burbot suggests that sperm competition may be intense in this species. This study demonstrates that sexual dimorphism can be subtle and is present in a seemingly monomorphic species—the burbot.

scholarly journals Effects of Bioactive Components of Sea Cucumber on the Serum, Liver Lipid Profile and Lipid Absorption

2012 ◽  
Vol 76 (12) ◽  
pp. 2214-2218 ◽  
Author(s):  
Xiao-Qian HU ◽  
Jie XU ◽  
Yong XUE ◽  
Zhao-Jie LI ◽  
Jing-Feng WANG ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Sea Cucumber ◽  
Liver Lipid ◽  
Lipid Absorption ◽  
Bioactive Components

Liver lipid as a source of embolic fat

1961 ◽  
Vol 16 (6) ◽  
pp. 1100-1102 ◽  
Author(s):  
Guy Owens ◽  
Joseph E. Sokal
Keyword(s):  
Technical Assistance ◽  
Liver Lipid ◽  
Organ Perfusion ◽  
Lipid Concentration ◽  
High Fat ◽  
Intracellular Lipid ◽  
Adult Rats ◽  
Experimental Animals ◽  
Clinical Observations ◽  
Fatty Livers

Little attention has been focused on the liver as a source of embolic fat. Despite this, clinical observations are available suggesting a relationship between fatty livers and the frequency and/or degree of fat embolization. By combining whole organ perfusion techniques and dietary production of fatty livers in experimental animals, a tool for evaluating the liver and its role in fat embolization has been developed. Fatty livers were produced in adult rats within 12 days by employing a high fat choline-free diet. One group of animals so prepared served as nonperfused tissue controls. Livers from normal and special dietary animals were removed and perfused for periods up to 4 hr. All tissues were frozen and then sectioned after 24-hr fixation in 10% formalin and stained with flaming red and hematoxylin. Nonperfused livers from animals on a choline-free diet revealed intense intracellular lipid concentration, but no fat emboli. Normal livers perfused for 3—4 hr were free of significant accumulation of embolic fat. In contrast, severe embolization was encountered in the perfused fatty livers. Note: With the Technical Assistance of Kornel Gerszi and Mary S. Northington Submitted on May 10, 1961

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