Coupling between Molecular and Plasmonic Resonances in Freestanding Dye−Gold Nanorod Hybrid Nanostructures

2008 ◽  
Vol 130 (21) ◽  
pp. 6692-6693 ◽  
Author(s):  
Weihai Ni ◽  
Zhi Yang ◽  
Huanjun Chen ◽  
Li Li ◽  
Jianfang Wang
Nano Letters ◽  
2011 ◽  
Vol 11 (6) ◽  
pp. 2296-2303 ◽  
Author(s):  
Tian Ming ◽  
Lei Zhao ◽  
Huanjun Chen ◽  
Kat Choi Woo ◽  
Jianfang Wang ◽  
...  

Nanomaterials ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 444
Author(s):  
Xuemeng Li ◽  
Yingshuting Wang ◽  
Quanying Fu ◽  
Yangyang Wang ◽  
Dongxu Ma ◽  
...  

Recently, biosensing based on weak coupling in plasmon-emitter hybrid nanostructures exhibits the merits of simplicity and high sensitivity, and attracts increasing attention as an emerging nano-sensor. In this study, we propose an innovative plasmon-regulated fluorescence resonance energy transfer (plasmon-regulated FRET) sensing strategy based on a plasmon-emitter hybrid nanostructure of gold nanorod-quantum dots (Au NR-QDs) by partially modifying QDs onto the surfaces of Au NRs. The Au NR-QDs showed good sensitivity and reversibility against refractive index change. We successfully employed the Au NR-QDs to fabricate nano-sensors for detecting a cancer biomarker of alpha fetoprotein with a limit of detection of 0.30 ng/mL, which displays that the sensitivity of the Au NR-QDs nano-sensor was effectively improved compared with the Au NRs based plasmonic sensing. Additionally, to demonstrate the universality of the plasmon-regulated FRET sensing strategy, another plasmon-emitter hybrid nano-sensor of Au nano-prism-quantum dots (Au NP-QDs) were constructed and applied for detecting a myocardial infarction biomarker of cardiac troponin I. It was first reported that the change of absorption spectra of plasmonic structure in a plasmon-emitter hybrid nanostructure was employed for analytes detection. The plasmon-regulated FRET sensing strategy described herein has potential utility to develop general sensing platforms for chemical and biological analysis.


2013 ◽  
Vol 1 (1) ◽  
pp. 28 ◽  
Author(s):  
Jiafang Li ◽  
Honglian Guo ◽  
Zhi-Yuan Li

Nanoscale ◽  
2017 ◽  
Vol 9 (23) ◽  
pp. 7750-7754 ◽  
Author(s):  
Linlin Song ◽  
Qiao Jiang ◽  
Jianbing Liu ◽  
Na Li ◽  
Qing Liu ◽  
...  

NANO ◽  
2014 ◽  
Vol 09 (03) ◽  
pp. 1450035
Author(s):  
LU ZHANG ◽  
YAN-JUAN TANG ◽  
YAN-JIE GUO ◽  
JIAN-JUN LUO ◽  
GUI-MIN SUN ◽  
...  

A novel core–shell hybrid nanostructure was constructed by employing gold nanorod ( AuNR ) combined with rhodamine B (RB) as a core and silica as a shell. The poly(sodium 4-styrenesulfonate) (PSS), a negatively charged polyelectrolyte, played the role of linker to electrostatically trap RB on AuNRs . Due to the fluorescence spectral overlap between RB and AuNRs at 560 nm, the red fluorescence and enhanced green fluorescence of the hybrid nanostructures were observed obviously, which is capable for dual-color labeling. To reduce toxic side effects of AuNRs , silica was coated on AuNRs as a shell to fabricate the novel core–shell hybrid nanostructure function as a dual-color labeling for cancer-cell imaging. The fabricated composite structures were characterized by transmission electron microscopy (TEM), absorption spectrum, fluorescence spectrum, zeta potential measurements and laser scanning confocal microscope (LSCM). The experiment results confirmed that the obtained hybrid nanostructures provided excellent photostability, biocompatibility and active surface for further biological functionalization. The novel composite structures may have great potential application in cell multicolor labeling and imaging instead of traditional fluorescent dyes.


Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1332
Author(s):  
Armando Hernandez-Garcia

Proteins and DNA exhibit key physical chemical properties that make them advantageous for building nanostructures with outstanding features. Both DNA and protein nanotechnology have growth notably and proved to be fertile disciplines. The combination of both types of nanotechnologies is helpful to overcome the individual weaknesses and limitations of each one, paving the way for the continuing diversification of structural nanotechnologies. Recent studies have implemented a synergistic combination of both biomolecules to assemble unique and sophisticate protein–DNA nanostructures. These hybrid nanostructures are highly programmable and display remarkable features that create new opportunities to build on the nanoscale. This review focuses on the strategies deployed to create hybrid protein–DNA nanostructures. Here, we discuss strategies such as polymerization, spatial directing and organizing, coating, and rigidizing or folding DNA into particular shapes or moving parts. The enrichment of structural DNA nanotechnology by incorporating protein nanotechnology has been clearly demonstrated and still shows a large potential to create useful and advanced materials with cell-like properties or dynamic systems. It can be expected that structural protein–DNA nanotechnology will open new avenues in the fabrication of nanoassemblies with unique functional applications and enrich the toolbox of bionanotechnology.


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